TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:In vitro inhibition of human recombinant Protein farnesyltransferase with respect to FPPMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Displacement of [35S]-labeled ligand from VLA4 in human Jurkat cells washed with buffer containing non activating Ca2+ and Mg2+ by competitive bindin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of VLA-4 receptor of Jurkat cells in BURJ assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Displacement of [35S]-labeled ligand from VLA4 in human Jurkat cells washed with buffer containing activating Mn2+ by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Displacement of [35S]-labeled ligand from VLA4 in human Jurkat cells washed with buffer containing non activating Ca2+ and Mg2+ by competitive bindin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of VLA4 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Displacement of [35S]-labeled ligand from VLA4 in human Jurkat cells washed with buffer containing non activating Ca2+ and Mg2+ by competitive bindin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Displacement of [35S]-labeled ligand from VLA4 in human Jurkat cells washed with buffer containing non activating Ca2+ and Mg2+ by competitive bindin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Displacement of [35S]-labeled ligand from VLA4 in human Jurkat cells washed with buffer containing non activating Ca2+ and Mg2+ by competitive bindin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Displacement of [35S]-labeled ligand from VLA4 in human Jurkat cells washed with buffer containing non activating Ca2+ and Mg2+ by competitive bindin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Displacement of [35S]-labeled ligand from VLA4 in human Jurkat cells washed with buffer containing non activating Ca2+ and Mg2+ by competitive bindin...More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human VLA4More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human VLA4 in presence of 90% human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of FLAG-tagged PHD2 expressed in baculovirus infected insect sf9 cells using biotinyl-DLDLEMLAPYIPMDDDFQL as substrate preincubated with c...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of FLAG-tagged PHD2 expressed in baculovirus infected insect sf9 cells using biotinyl-DLDLEMLAPYIPMDDDFQL as substrate preincubated with c...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of FLAG-tagged PHD2 expressed in baculovirus infected insect sf9 cells using biotinyl-DLDLEMLAPYIPMDDDFQL as substrate preincubated with c...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of FLAG-tagged PHD2 expressed in baculovirus infected insect sf9 cells using biotinyl-DLDLEMLAPYIPMDDDFQL as substrate preincubated with c...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of FLAG-tagged PHD2 expressed in baculovirus infected insect sf9 cells using biotinyl-DLDLEMLAPYIPMDDDFQL as substrate preincubated with c...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of FLAG-tagged PHD2 expressed in baculovirus infected insect sf9 cells using biotinyl-DLDLEMLAPYIPMDDDFQL as substrate preincubated with c...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of FLAG-tagged PHD2 expressed in baculovirus infected insect sf9 cells using biotinyl-DLDLEMLAPYIPMDDDFQL as substrate preincubated with c...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of FLAG-tagged PHD2 expressed in baculovirus infected insect sf9 cells using biotinyl-DLDLEMLAPYIPMDDDFQL as substrate preincubated with c...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of FLAG-tagged PHD2 expressed in baculovirus infected insect sf9 cells using biotinyl-DLDLEMLAPYIPMDDDFQL as substrate preincubated with c...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of FLAG-tagged PHD2 expressed in baculovirus infected insect sf9 cells using biotinyl-DLDLEMLAPYIPMDDDFQL as substrate preincubated with c...More data for this Ligand-Target Pair