Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of PDK1 (unknown origin)More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Factor IX is a key component of the plasma system that forms a fibrin clot at a site of vascular injury. The activity of Factor IXa is measured by mo...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of PDK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant full length human His-tagged AURA expressed in Baculovirus expression system in presence of ATP measured by Bradford protei...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant full length human His-tagged AURA expressed in Baculovirus expression system in presence of ATP measured by Bradford protei...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 103nMAssay Description:Factor IX is a key component of the plasma system that forms a fibrin clot at a site of vascular injury. The activity of Factor IXa is measured by mo...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 103nMAssay Description:Inhibition of recombinant full length human His-tagged PDK1 expressed in Baculovirus expression system in presence of ATP measured by Bradford protei...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 103nMAssay Description:Inhibition of recombinant full length human His-tagged PDK1 expressed in Baculovirus expression system in presence of ATP measured by Bradford protei...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 112nMAssay Description:Inhibition of PDK1 (unknown origin) by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 112nMAssay Description:Factor IX is a key component of the plasma system that forms a fibrin clot at a site of vascular injury. The activity of Factor IXa is measured by mo...More data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Inhibition of recombinant full length human His-tagged AURA expressed in Baculovirus expression system in presence of ATP measured by Bradford protei...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 134nMAssay Description:Inhibition of recombinant full length human His-tagged PDK1 expressed in Baculovirus expression system in presence of ATP measured by Bradford protei...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 148nMAssay Description:Inhibition of recombinant full length human His-tagged PDK1 expressed in Baculovirus expression system in presence of ATP measured by Bradford protei...More data for this Ligand-Target Pair
Affinity DataIC50: 193nMAssay Description:Inhibition of recombinant full length human His-tagged AURA expressed in Baculovirus expression system in presence of ATP measured by Bradford protei...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Antagonist activity at mouse TLR4 expressed in HEK293 cells co-transfected with mouse MD-2/CD14 assessed as inhibition of LPS-stimulated receptor sig...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human TLR4 expressed in HEK293 cells co-transfected with human MD-2/CD14 assessed as inhibition of LPS-stimulated receptor sig...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Binding affinity to CD14/MD2 (unknown origin) expressed in HEK-Blue cells co-expressing TLR4 assessed as inhibition of LPS-induced TLR4 signaling pre...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 245nMAssay Description:Factor IX is a key component of the plasma system that forms a fibrin clot at a site of vascular injury. The activity of Factor IXa is measured by mo...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 245nMAssay Description:Factor IX is a key component of the plasma system that forms a fibrin clot at a site of vascular injury. The activity of Factor IXa is measured by mo...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 245nMAssay Description:Inhibition of recombinant full length human His-tagged PDK1 expressed in Baculovirus expression system in presence of ATP measured by Bradford protei...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 245nMAssay Description:Inhibition of recombinant full length human His-tagged PDK1 expressed in Baculovirus expression system in presence of ATP measured by Bradford protei...More data for this Ligand-Target Pair
Affinity DataIC50: 272nMAssay Description:Inhibition of GSK3beta (unknown origin) in presence of 10 uM ATP incubated for 1 hr by Z'Lyte assayMore data for this Ligand-Target Pair
Affinity DataIC50: 274nMAssay Description:Inhibition of CHK1 (unknown origin) in presence of 10 uM ATP incubated for 1 hr by Z'Lyte assayMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of PDK1 (unknown origin) incubated for 1 hr by Z'Lyte assayMore data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition concentration against human adenosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 356nMAssay Description:Inhibition of BuChE (unknown origin) pre-incubated for 20 mins before S-Butyrylthiocholine iodide substrate addition by Ellman reagent based spectrop...More data for this Ligand-Target Pair
Affinity DataIC50: 378nMAssay Description:Inhibition of BuChE (unknown origin) pre-incubated for 20 mins before S-Butyrylthiocholine iodide substrate addition by Ellman reagent based spectrop...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 416nMAssay Description:Inhibition of recombinant full length human His-tagged PDK1 expressed in Baculovirus expression system in presence of ATP measured by Bradford protei...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 416nMAssay Description:Factor IX is a key component of the plasma system that forms a fibrin clot at a site of vascular injury. The activity of Factor IXa is measured by mo...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 416nMAssay Description:Inhibition of PDK1 (unknown origin) by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
Affinity DataIC50: 452nMAssay Description:Inhibition of BuChE (unknown origin) pre-incubated for 20 mins before S-Butyrylthiocholine iodide substrate addition by Ellman reagent based spectrop...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 455nMAssay Description:Inhibition of recombinant full length human His-tagged PDK1 expressed in Baculovirus expression system in presence of ATP measured by Bradford protei...More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 475nMAssay Description:Inhibition of recombinant full length human His-tagged PDK1 expressed in Baculovirus expression system in presence of ATP measured by Bradford protei...More data for this Ligand-Target Pair
Affinity DataIC50: 507nMAssay Description:Inhibition of BuChE (unknown origin) pre-incubated for 20 mins before S-Butyrylthiocholine iodide substrate addition by Ellman reagent based spectrop...More data for this Ligand-Target Pair
Affinity DataIC50: 511nMAssay Description:Inhibition concentration against human adenosine kinaseMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 512nMAssay Description:Factor IX is a key component of the plasma system that forms a fibrin clot at a site of vascular injury. The activity of Factor IXa is measured by mo...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 512nMAssay Description:Inhibition of PDK1 (unknown origin) by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of LPS-induced TLR4 activation (unknown origin) expressed in HEK293 Blue cells compound treated for 30 mins prior LPS treatment measured a...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Antagonist activity at human TLR4 expressed in HEK293 cells co-transfected with human MD-2/CD14 assessed as inhibition of LPS-stimulated receptor sig...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Antagonist activity at mouse TLR4 expressed in HEK293 cells co-transfected with mouse MD-2/CD14 assessed as inhibition of LPS-stimulated receptor sig...More data for this Ligand-Target Pair
Affinity DataIC50: 611nMAssay Description:Inhibition of recombinant full length human His-tagged AURA expressed in Baculovirus expression system in presence of ATP measured by Bradford protei...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Inhibition concentration against human adenosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 678nMAssay Description:Inhibition concentration against human adenosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Binding affinity to CD14/MD2 (unknown origin) expressed in HEK-Blue cells co-expressing TLR4 assessed as inhibition of LPS-induced TLR4 signaling pre...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Antagonist activity at mouse TLR4 expressed in HEK293 cells co-transfected with mouse MD-2/CD14 assessed as inhibition of LPS-stimulated receptor sig...More data for this Ligand-Target Pair
Affinity DataIC50: 884nMAssay Description:Inhibition of GSK3alpha (unknown origin) in presence of 10 uM ATP incubated for 1 hr by Z'Lyte assayMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 980nMAssay Description:Inhibition of PDK1 (unknown origin) incubated for 1 hr by Z'Lyte assayMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 998nMAssay Description:Inhibition of PDK1 (unknown origin) in presence of 25 uM ATP incubated for 1 hr by Z'Lyte assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of LPS-induced TLR4 activation (unknown origin) expressed in HEK293 Blue cells compound treated for 30 mins prior LPS treatment measured a...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University Of Pisa
Curated by ChEMBL
University Of Pisa
Curated by ChEMBL
Affinity DataIC50: 1.34E+3nMAssay Description:Factor IX is a key component of the plasma system that forms a fibrin clot at a site of vascular injury. The activity of Factor IXa is measured by mo...More data for this Ligand-Target Pair