Found 99 with Last Name = 'tambe' and Initial = 's' 
Affinity DataIC50: 7nMAssay Description:Antagonist activity at rat GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induc...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 14.6nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 14.6nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 17.6nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
TargetAcetyl-CoA acetyltransferase, mitochondrial(Homo sapiens)
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of human ACAT1 in HepG2 cells assessed as inhibition of triglyceride synthesis incubated for 1 hrs followed by 13C-addition of 13C-oleic a...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-additi...More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Antagonist activity at rat GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induc...More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Dr.Vishwanath Karad Mit World Peace University
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant human DGAT1 expressed in Sf9 cell membrane assessed as inhibition of triglyceride synthesis incubated for 1 hrs by LC-MS-ba...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Antagonist activity at rat GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induc...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
Affinity DataIC50: 115nMAssay Description:Antagonist activity at rat GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induc...More data for this Ligand-Target Pair
Affinity DataIC50: 135nMAssay Description:Antagonist activity at rat GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induc...More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-ind...More data for this Ligand-Target Pair
