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Found 54 with Last Name = 'slocum' and Initial = 'st'
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50609010(CHEMBL5276728)
Affinity DataKi:  34nMAssay Description:Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50609010(CHEMBL5276728)
Affinity DataKi:  49nMAssay Description:Displacement of [125]IBNtxA from mouse DOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataKi:  79nMAssay Description:Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))TBA
LigandPNGBDBM50609010(CHEMBL5276728)
Affinity DataKi:  125nMAssay Description:Displacement of [125]IBNtxA from mouse KOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50528407(CHEMBL4561016)
Affinity DataKi:  209nMAssay Description:Displacement of [3H]LSD from recombinant human 5HT2B stably expressed in HEK cell membranes incubated for 90 mins under dark condition by microbeta s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50528407(CHEMBL4561016)
Affinity DataKi:  209nMAssay Description:Displacement of [3H]LSD from recombinant human 5HT2B stably expressed in HEK cell membranes incubated for 90 mins under dark condition by microbeta s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50528406(CHEMBL4465512)
Affinity DataKi:  212nMAssay Description:Antagonist activity at human 5HT2B receptor expressed in Flp-In-HEK cells co-expressing Gq assessed as inhibition of 5HT-induced stimulation of calci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataKi:  216nMAssay Description:Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50528405(CHEMBL4449712)
Affinity DataKi:  219nMAssay Description:Displacement of [3H]LSD from recombinant human 5HT2B stably expressed in HEK cell membranes incubated for 90 mins under dark condition by microbeta s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50528405(CHEMBL4449712)
Affinity DataKi:  219nMAssay Description:Displacement of [3H]LSD from recombinant human 5HT2B stably expressed in HEK cell membranes incubated for 90 mins under dark condition by microbeta s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50528406(CHEMBL4465512)
Affinity DataKi:  295nMAssay Description:Displacement of [3H]LSD from recombinant human 5HT2B stably expressed in HEK cell membranes incubated for 90 mins under dark condition by microbeta s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50528408(CHEMBL4436453)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]ZM241385 from recombinant human A2A receptor incubated for 90 mins under dark condition by microbeta scintillation methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50528405(CHEMBL4449712)
Affinity DataKi:  310nMAssay Description:Antagonist activity at human 5HT2B receptor expressed in Flp-In-HEK cells co-expressing Gq assessed as inhibition of 5HT-induced stimulation of calci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50528406(CHEMBL4465512)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]LSD from recombinant human 5HT2B stably expressed in HEK cell membranes incubated for 90 mins under dark condition by microbeta s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50566316(CHEMBL4859858)
Affinity DataKi:  578nMAssay Description:Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))TBA
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataKi:  649nMAssay Description:Displacement of [125]IBNtxA from mouse KOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50566317(CHEMBL4848517)
Affinity DataKi:  666nMAssay Description:Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50528407(CHEMBL4561016)
Affinity DataKi:  678nMAssay Description:Antagonist activity at human 5HT2B receptor expressed in Flp-In-HEK cells co-expressing Gq assessed as inhibition of 5HT-induced stimulation of calci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))TBA
LigandPNGBDBM50566317(CHEMBL4848517)
Affinity DataKi:  883nMAssay Description:Displacement of [125]IBNtxA from mouse KOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataKi:  1.15E+3nMAssay Description:Displacement of [125]IBNtxA from mouse DOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))TBA
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataKi:  1.18E+3nMAssay Description:Displacement of [125]IBNtxA from mouse KOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))TBA
LigandPNGBDBM50609011(CHEMBL5287921)
Affinity DataKi:  1.27E+3nMAssay Description:Displacement of [125]IBNtxA from mouse KOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50609011(CHEMBL5287921)
Affinity DataKi:  1.68E+3nMAssay Description:Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50528408(CHEMBL4436453)
Affinity DataKi:  1.70E+3nMAssay Description:Inverse agonist activity at recombinant human A2A receptor expressed in HEK293T cells co-expressing Gs assessed as decrease in cAMP accumulation meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataKi:  1.88E+3nMAssay Description:Displacement of [125]IBNtxA from mouse DOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))TBA
LigandPNGBDBM50566316(CHEMBL4859858)
Affinity DataKi:  2.20E+3nMAssay Description:Displacement of [125]IBNtxA from mouse KOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50609011(CHEMBL5287921)
Affinity DataKi:  3.24E+3nMAssay Description:Displacement of [125]IBNtxA from mouse DOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50566317(CHEMBL4848517)
Affinity DataKi:  3.40E+3nMAssay Description:Displacement of [125]IBNtxA from mouse DOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50609009(CHEMBL56717)
Affinity DataKi:  4.14E+3nMAssay Description:Displacement of [125]IBNtxA from mouse DOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50528408(CHEMBL4436453)
Affinity DataKi:  6.70E+3nMAssay Description:Antagonist activity at recombinant human A2A receptor expressed in HEK293T cells co-expressing Gs assessed as inhibition of NECA-stimulated cAMP accu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50609009(CHEMBL56717)
Affinity DataKi:  6.90E+3nMAssay Description:Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))TBA
LigandPNGBDBM50609009(CHEMBL56717)
Affinity DataKi:  7.18E+3nMAssay Description:Displacement of [125]IBNtxA from mouse KOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50566316(CHEMBL4859858)
Affinity DataKi:  7.95E+3nMAssay Description:Displacement of [125]IBNtxA from mouse DOR stably expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50609010(CHEMBL5276728)
Affinity DataIC50:  1.10E+3nMAssay Description:Antagonist activity at mouse DOR expressed in CHO cell membranes assessed as inhibition of DPDPE induced [35S]-GTPgammaS binding incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50566317(CHEMBL4848517)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at mouse DOR expressed in CHO cell membranes assessed as inhibition of DPDPE induced [35S]-GTPgammaS binding incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataIC50:  1.09E+4nMAssay Description:Antagonist activity at mouse MOR expressed in CHO cell membranes assessed as inhibition of DAMGO induced [35S]-GTPgammaS binding incubated for 60 min...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataIC50:  1.26E+4nMAssay Description:Antagonist activity at mouse DOR expressed in CHO cell membranes assessed as inhibition of DPDPE induced [35S]-GTPgammaS binding incubated for 60 min...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))TBA
LigandPNGBDBM50566317(CHEMBL4848517)
Affinity DataEC50:  3.59E+3nMAssay Description:Agonist activity at mouse KOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))TBA
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataEC50:  1.36E+3nMAssay Description:Agonist activity at mouse KOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))TBA
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataEC50:  858nMAssay Description:Agonist activity at mouse KOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))TBA
LigandPNGBDBM50609010(CHEMBL5276728)
Affinity DataEC50:  166nMAssay Description:Agonist activity at mouse KOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))TBA
LigandPNGBDBM50609011(CHEMBL5287921)
Affinity DataEC50:  1.14E+3nMAssay Description:Agonist activity at mouse KOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50519927(CHEMBL4546925)
Affinity DataEC50:  73nMAssay Description:Partial agonist activity at mouse MOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by sci...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50609011(CHEMBL5287921)
Affinity DataEC50:  5.78E+3nMAssay Description:Agonist activity at mouse MOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50609010(CHEMBL5276728)
Affinity DataEC50:  68nMAssay Description:Agonist activity at mouse MOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50474151(CHEMBL292521)
Affinity DataEC50:  422nMAssay Description:Agonist activity at mouse MOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50566316(CHEMBL4859858)
Affinity DataEC50:  6.23E+3nMAssay Description:Agonist activity at mouse MOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMu-type opioid receptor(MOUSE)TBA
LigandPNGBDBM50566317(CHEMBL4848517)
Affinity DataEC50:  9.38E+3nMAssay Description:Agonist activity at mouse MOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50528405(CHEMBL4449712)
Affinity DataKd:  1.10E+3nMAssay Description:Agonist activity at human MT2 receptor expressed in HTLA cells assessed as stimulation of beta-arrestin recruitment incubated for 16 to 20 hrs by bri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50528405(CHEMBL4449712)
Affinity DataKd:  5.90E+3nMAssay Description:Agonist activity at human MT1 receptor expressed in HTLA cells assessed as stimulation of beta-arrestin recruitment incubated for 16 to 20 hrs by bri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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