Affinity DataIC50: 52nMpH: 7.5 T: 2°CAssay Description:The IC50 for the different compounds was determined with Invitrogen Z'-LYTE kinase assay kit Ser/Thr 1 peptide PV3174 by following the manufactur...More data for this Ligand-Target Pair
Affinity DataIC50: 79.8nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
Affinity DataIC50: 97.9nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
Affinity DataIC50: 117nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
Affinity DataIC50: 163nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
Affinity DataIC50: 185nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
Affinity DataIC50: 224nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
Affinity DataIC50: 876nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 930nMAssay Description:Inhibition of IGF1R after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 930nMAssay Description:Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 940nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Inhibition of VEGFR3 after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 980nMAssay Description:Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 980nMAssay Description:Noncompetitive inhibition of EGFR after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 990nMAssay Description:Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Noncompetitive inhibition of EGFR after 30 mins by chemiluminescence ELISA in presence of 250 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of EGFR after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+3nMAssay Description:Noncompetitive inhibition of EGFR after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.01E+3nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.02E+3nMAssay Description:Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 250 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.04E+3nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 250 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.06E+3nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of VEGFR2 after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.07E+3nMAssay Description:Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of IGF1R after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.07E+3nMAssay Description:Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.09E+3nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of EGFR after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+3nMAssay Description:Noncompetitive inhibition of EGFR after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+3nMAssay Description:Noncompetitive inhibition of EGFR after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+3nMAssay Description:Noncompetitive inhibition of EGFR after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.17E+3nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.22E+3nMAssay Description:Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 250 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.22E+3nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of EGFR after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of EGFR after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of VEGFR3 after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.33E+3nMAssay Description:Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of EGFR after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.45E+3nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.48E+3nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 250 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMpH: 7.5 T: 2°CAssay Description:The IC50 for the different compounds was determined with Invitrogen Z'-LYTE kinase assay kit Ser/Thr 1 peptide PV3174 by following the manufactur...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of VEGFR2 after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 1.56E+3nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair