Affinity DataKi: 3.70nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.40nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.5nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.10nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.10nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
Affinity DataKi: 10.5nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
Affinity DataKi: 11.3nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
Affinity DataKi: 22.3nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
Affinity DataKi: 111nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Australian National University
Curated by ChEMBL
Australian National University
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Compound was evaluated for its inhibitory activity against Leucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Compound was evaluated for its inhibitory activity against VRS (valyl tRNA synthetase) from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Inhibition of DHFR using dihydrofolate as substrate following 3 mins substrate preincubation measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Compound was evaluated for its inhibitory activity against VRS (valyl tRNA synthetase) from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Binding affinity at FGF1More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Compound was evaluated for its inhibitory activity against VRS (valyl tRNA synthetase) from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition of DHFR using dihydrofolate as substrate following 3 mins substrate preincubation measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 910nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Australian National University
Curated by ChEMBL
Australian National University
Curated by ChEMBL
Affinity DataIC50: 1.55E+3nMAssay Description:Compound was evaluated for its inhibitory activity against Leucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibitory activity against human platelet heparanase by Microcon ultrafiltration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibitory activity against human platelet heparanase by Microcon ultrafiltration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibitory activity against human platelet heparanase by Microcon ultrafiltration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibitory activity against human platelet heparanase by Microcon ultrafiltration assayMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Australian National University
Curated by ChEMBL
Australian National University
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Compound was evaluated for its inhibitory activity against Leucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
Affinity DataIC50: 3.27E+3nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+3nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 1.46E+4nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
Affinity DataIC50: 2.23E+4nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DHFR using dihydrofolate as substrate following 3 mins substrate preincubation measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Australian National University
Curated by ChEMBL
Australian National University
Curated by ChEMBL
Affinity DataIC50: 1.86E+5nMAssay Description:Compound was evaluated for its inhibitory activity against Leucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of DHFR using dihydrofolate as substrate following 3 mins substrate preincubation measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of DHFR using dihydrofolate as substrate following 3 mins substrate preincubation measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair