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Found 88 with Last Name = 'kim' and Initial = 'th'
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50439332(CHEMBL2419745)
Affinity DataKi:  113nMAssay Description:Inhibition of human t-PAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataKi:  1.51E+3nMAssay Description:Inhibition of human t-PAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50439332(CHEMBL2419745)
Affinity DataKi:  2.25E+3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataKi:  3.68E+3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50439332(CHEMBL2419745)
Affinity DataKi:  7.43E+3nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50038001((2R,4R)-1-((S)-5-(diaminomethyleneamino)-2-(3-meth...)
Affinity DataKi:  5.30E+4nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50038001((2R,4R)-1-((S)-5-(diaminomethyleneamino)-2-(3-meth...)
Affinity DataKi:  8.78E+4nMAssay Description:Inhibition of human t-PAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50038001((2R,4R)-1-((S)-5-(diaminomethyleneamino)-2-(3-meth...)
Affinity DataKi:  2.57E+5nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121552(US8729273, 22)
Affinity DataIC50:  2.10nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121532(US8729273, 2)
Affinity DataIC50:  2.80nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121531(US8729273, 1)
Affinity DataIC50:  3.40nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121536(US8729273, 6)
Affinity DataIC50:  3.80nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121534(US8729273, 4)
Affinity DataIC50:  4.5nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121547(US8729273, 17)
Affinity DataIC50:  4.60nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121539(US8729273, 9)
Affinity DataIC50:  4.60nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121550(US8729273, 20)
Affinity DataIC50:  4.70nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121543(US8729273, 13)
Affinity DataIC50:  4.80nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121535(US8729273, 5)
Affinity DataIC50:  5nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121559(US8729273, 29)
Affinity DataIC50:  5nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121540(US8729273, 10)
Affinity DataIC50:  5.20nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121541(US8729273, 11)
Affinity DataIC50:  5.40nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121533(US8729273, 3)
Affinity DataIC50:  6nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121554(US8729273, 24)
Affinity DataIC50:  6.20nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121551(US8729273, 21)
Affinity DataIC50:  6.20nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121537(US8729273, 7)
Affinity DataIC50:  6.70nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121538(US8729273, 8)
Affinity DataIC50:  6.90nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121555(US8729273, 25)
Affinity DataIC50:  8.5nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121553(US8729273, 23)
Affinity DataIC50:  10nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121557(US8729273, 27)
Affinity DataIC50:  11nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121542(US8729273, 12)
Affinity DataIC50:  11.6nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121544(US8729273, 14)
Affinity DataIC50:  12nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121548(US8729273, 18)
Affinity DataIC50:  13nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121560(US8729273, 30)
Affinity DataIC50:  17nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121549(US8729273, 19)
Affinity DataIC50:  24nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121558(US8729273, 28)
Affinity DataIC50:  24nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121561(US8729273, 31)
Affinity DataIC50:  40nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  200nMAssay Description:Inhibition of COX2 assessed as inhibition of PGE2 production using arachidonic acid as substrate after 10 mins by ELISAMore data for this Ligand-Target Pair
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Daegu University

Curated by ChEMBL
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  400nMAssay Description:Inhibition of porcine pancreatic lipase using pNPB as substrate measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Daegu University

Curated by ChEMBL
LigandPNGBDBM50262486(CHEMBL2354678)
Affinity DataIC50:  500nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Daegu University

Curated by ChEMBL
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of pig pancreatic lipase assessed as p-NPB hydrolysis by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Daegu University

Curated by ChEMBL
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  600nMpH: 6.8Assay Description:Particularly, pancreatic lipase inhibiting activity was measured by the conventional method known to those in the art (Kim, J. H.; Kim, H. J.; Park, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Daegu University

Curated by ChEMBL
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of pig pancreatic lipase assessed as hydrolysis of p-nitrophenylbutyrate to p-nitrophenolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391834(CHEMBL2147024)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of recombinant human ERG channel IKr expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391830(CHEMBL2147020)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of recombinant human ERG channel IKr expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391831(CHEMBL2147021)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of recombinant human ERG channel IKr expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Lg Life Sciences

US Patent
LigandPNGBDBM121556(US8729273, 26)
Affinity DataIC50:  3.94E+3nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391832(CHEMBL2147022)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of recombinant human ERG channel IKr expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Daegu University

Curated by ChEMBL
LigandPNGBDBM50262488(CHEMBL4067236)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50036635(CHEMBL3354313)
Affinity DataIC50:  5.25E+3nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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