Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human11beta-HSD1 in human PBMC cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human11beta-HSD1 in human PBMC cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMC after 30 mins by gamma counterMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human11beta-HSD1 in human PBMC cellsMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human11beta-HSD1 in human PBMC cellsMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human11beta-HSD1 in human PBMC cellsMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of 11beta-HSD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMC after 30 mins by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human CCR2-mediated Erk phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMC after 30 mins by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of 11beta-HSD1 (unknown origin)More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human11beta-HSD1 in human PBMC cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMC after 30 mins by gamma counterMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of 11beta-HSD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMC after 30 mins by gamma counterMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human11beta-HSD1 in human PBMC cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMC after 30 mins by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of 11beta-HSD1 (unknown origin)More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human11beta-HSD1 in human PBMC cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMC after 30 mins by gamma counterMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human11beta-HSD1 in human PBMC cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMC after 30 mins by gamma counterMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of 11beta-HSD1 (unknown origin)More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human11beta-HSD1 in human PBMC cellsMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of 11beta-HSD1 (unknown origin)More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibition of 11beta-HSD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human CCR2-mediated intracellular calcium mobilization by cell based assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of 11beta-HSD1 (unknown origin)More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of 11beta-HSD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMC after 30 mins by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Inhibition of 11beta-HSD1 (unknown origin)More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMC after 30 mins by gamma counterMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of 11beta-HSD1 (unknown origin)More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of 11beta-HSD1 (unknown origin)More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of 11beta-HSD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human11beta-HSD1 in human PBMC cellsMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of 11beta-HSD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10.3nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMC after 30 mins by gamma counterMore data for this Ligand-Target Pair