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Found 173 with Last Name = 'trizna' and Initial = 'w'
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50296010(2-isobutyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294706(4-((2-chlorobenzyl)(3-methyl-1-(1-methyl-1H-tetraz...)
Affinity DataIC50:  5nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298033((S)-ethyl 2-(3-((3-chloro-4-cyanophenyl)(2-chlorob...)
Affinity DataIC50:  8nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298032((S)-2-chloro-4-((2-chlorobenzyl)(1-(cyanomethyl)py...)
Affinity DataIC50:  8nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298210((S)-2-chloro-4-((2,5-dichlorobenzyl)(1-ethyl-5-oxo...)
Affinity DataIC50:  10nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298208((S)-2-chloro-4-((2-chloro-5-fluorobenzyl)(1-ethyl-...)
Affinity DataIC50:  10nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298207((S)-2-chloro-4-((2-chlorobenzyl)(1-isopropyl-5-oxo...)
Affinity DataIC50:  10nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294702(4-((2-chlorobenzyl)(1-(1-methyl-1H-tetrazol-5-yl)e...)
Affinity DataIC50:  13nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294703(4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3...)
Affinity DataIC50:  13nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298030((S)-2-chloro-4-((2-chlorobenzyl)(1-(3,3,3-trifluor...)
Affinity DataIC50:  13nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294705(4-((2-chlorobenzyl)(1-(1-methyl-1H-tetrazol-5-yl)p...)
Affinity DataIC50:  13nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294715(4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3...)
Affinity DataIC50:  13nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50296011(2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin...)
Affinity DataIC50:  13nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294696(4-((2-chlorobenzyl)(1-(2-methylthiazol-4-yl)ethyl)...)
Affinity DataIC50:  13nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298219((R)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...)
Affinity DataIC50:  15nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298209((S)-2-chloro-4-((1-ethyl-5-oxopyrrolidin-3-yl)(2-m...)
Affinity DataIC50:  15nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294707(4-((2-chlorobenzyl)(1-(1-ethyl-1H-tetrazol-5-yl)et...)
Affinity DataIC50:  16nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294714(4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3...)
Affinity DataIC50:  16nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294710(2-chloro-4-(isobutyl(3-methyl-1-(1-methyl-1H-tetra...)
Affinity DataIC50:  16nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298028((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...)
Affinity DataIC50:  16nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294712((S)-2-chloro-4-((cyclobutylmethyl)(3-methyl-1-(1-m...)
Affinity DataIC50:  16nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298029((S)-2-chloro-4-((2-chlorobenzyl)(1-isopropylpyrrol...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50296009(2-ethyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)...)
Affinity DataIC50:  20nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294700(4-((2-chlorobenzyl)(1-(1-methyl-1H-imidazol-2-yl)e...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298043((S)-2-chloro-4-((2-chlorobenzyl)(1-methylpyrrolidi...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294699(4-((2-chlorobenzyl)(1-(3-methylisoxazol-5-yl)ethyl...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298035((S)-2-chloro-4-((2-chlorobenzyl)(1-(pyridin-2-ylme...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298212((S)-2-chloro-4-((2-fluorobenzyl)(1-methyl-5-oxopyr...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298211((S)-2-chloro-4-((1-isopropyl-5-oxopyrrolidin-3-yl)...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298206((S)-2-chloro-4-((2-chlorobenzyl)(1-methyl-5-oxopyr...)
Affinity DataIC50:  25nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298031((S)-2-chloro-4-((2-chlorobenzyl)(1-(2-methoxyethyl...)
Affinity DataIC50:  25nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294697(4-((2-chlorobenzyl)(1-(1-methyl-1H-pyrazol-5-yl)et...)
Affinity DataIC50:  25nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294709(4-((2-(trifluoromethyl)benzyl)(3-methyl-1-(1-methy...)
Affinity DataIC50:  25nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298213((S)-2-chloro-4-((2,3-difluorobenzyl)(1-methyl-5-ox...)
Affinity DataIC50:  25nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298214((S)-2-chloro-4-((1-methyl-5-oxopyrrolidin-3-yl)(2-...)
Affinity DataIC50:  25nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294717(4-((2-chlorobenzyl)(3-methyl-1-(4-methyl-4H-1,2,4-...)
Affinity DataIC50:  25nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294716(4-((2-chlorobenzyl)(2-methyl-1-(4-methyl-4H-1,2,4-...)
Affinity DataIC50:  32nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294701(4-((2-chlorobenzyl)(1-(5-methyl-1,3,4-oxadiazol-2-...)
Affinity DataIC50:  32nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294724(2-((2-chlorobenzyl)(3-chloro-4-cyanophenyl)amino)-...)
Affinity DataIC50:  32nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294708(4-((2-chlorobenzyl)(1-(1-isopropyl-1H-tetrazol-5-y...)
Affinity DataIC50:  32nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294698(4-((2-chlorobenzyl)(1-(1-methyl-1H-1,2,3-triazol-4...)
Affinity DataIC50:  40nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294720(2-chloro-4-((cyclohexylmethyl)(1-(4-methyl-4H-1,2,...)
Affinity DataIC50:  40nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298041((S)-4-(benzyl(1-methylpyrrolidin-3-yl)amino)-2-chl...)
Affinity DataIC50:  40nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294711(2-chloro-4-((cyclobutylmethyl)(3-methyl-1-(1-methy...)
Affinity DataIC50:  40nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294698(4-((2-chlorobenzyl)(1-(1-methyl-1H-1,2,3-triazol-4...)
Affinity DataIC50:  40nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50296015(2-(4-(5-(3-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3...)
Affinity DataIC50:  40nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50296003(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic ...)
Affinity DataIC50:  40nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298046((S)-2-chloro-4-((2,6-dichlorobenzyl)(1-methylpyrro...)
Affinity DataIC50:  40nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298215((S)-2-chloro-4-((2,4-difluorobenzyl)(1-methyl-5-ox...)
Affinity DataIC50:  40nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50294704(4-((2-chlorobenzyl)((1-methyl-1H-tetrazol-5-yl)met...)
Affinity DataIC50:  50nMAssay Description:Binding affinity to progesterone receptor ligand binding domain by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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