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Found 129 with Last Name = 'ying' and Initial = 'w'
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131811(US8835464, 13b | US9206162, 13b)
Affinity DataIC50:  27nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131811(US8835464, 13b | US9206162, 13b)
Affinity DataIC50:  27nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131810(US8835464, 12b | US9206162, 12b)
Affinity DataIC50:  29nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131810(US8835464, 12b | US9206162, 12b)
Affinity DataIC50:  29nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131817(US8835464, 1d | US9206162, 1d)
Affinity DataIC50:  30nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131817(US8835464, 1d | US9206162, 1d)
Affinity DataIC50:  30nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Madrigal Pharmaceuticals

US Patent
LigandPNGBDBM297485(US10117944, Compound SDC-TRAP-0249)
Affinity DataIC50:  36nMAssay Description:HER2 has emerged as a key target for anticancer drugs due to its intrinsic involvement in the phosphatidylinositol-3-kinase-Akt/protein kinase B (PI3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Madrigal Pharmaceuticals

US Patent
LigandPNGBDBM297487(US10117944, Compound SDC-TRAP-0247)
Affinity DataIC50:  36nMAssay Description:HER2 has emerged as a key target for anticancer drugs due to its intrinsic involvement in the phosphatidylinositol-3-kinase-Akt/protein kinase B (PI3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Madrigal Pharmaceuticals

US Patent
LigandPNGBDBM297478(US10117944, Compound SDC-TRAP-0248)
Affinity DataIC50:  37nMAssay Description:HER2 has emerged as a key target for anticancer drugs due to its intrinsic involvement in the phosphatidylinositol-3-kinase-Akt/protein kinase B (PI3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131812(US8835464, 14b | US9206162, 14b)
Affinity DataIC50:  38nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131812(US8835464, 14b | US9206162, 14b)
Affinity DataIC50:  38nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131807(BDBM194680 | US8835464, 9b)
Affinity DataIC50:  40nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131807(BDBM194680 | US8835464, 9b)
Affinity DataIC50:  40nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131815(US8835464, 17b | US9206162, 17b)
Affinity DataIC50:  46nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131815(US8835464, 17b | US9206162, 17b)
Affinity DataIC50:  46nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131822(US8835464, 6d | US8835464, 7d | US9206162, 7d)
Affinity DataIC50:  47nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131822(US8835464, 6d | US8835464, 7d | US9206162, 7d)
Affinity DataIC50:  47nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131833(US8835464, 19d | US9206162, 19d)
Affinity DataIC50:  49nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131833(US8835464, 19d | US9206162, 19d)
Affinity DataIC50:  49nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131814(US8835464, 16b | US9206162, 16b)
Affinity DataIC50:  56nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131814(US8835464, 16b | US9206162, 16b)
Affinity DataIC50:  56nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131806(BDBM194677 | US8835464, 7b)
Affinity DataIC50:  58nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131806(BDBM194677 | US8835464, 7b)
Affinity DataIC50:  58nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131822(US8835464, 6d | US8835464, 7d | US9206162, 7d)
Affinity DataIC50:  58nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131822(US8835464, 6d | US8835464, 7d | US9206162, 7d)
Affinity DataIC50:  58nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131813(US8835464, 15b | US9206162, 15b)
Affinity DataIC50:  79nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131813(US8835464, 15b | US9206162, 15b)
Affinity DataIC50:  79nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131832(US8835464, 17d | US9206162, 17d)
Affinity DataIC50:  85nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131832(US8835464, 17d | US9206162, 17d)
Affinity DataIC50:  85nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM176684(US9120745, 3)
Affinity DataIC50:  88nMT: 2°CAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM176682(US9120745, 2)
Affinity DataIC50:  90nMT: 2°CAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131827(US8835464, 11d | US9206162, 11d)
Affinity DataIC50:  93nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131827(US8835464, 11d | US9206162, 11d)
Affinity DataIC50:  93nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Madrigal Pharmaceuticals

US Patent
LigandPNGBDBM297479(US10117944, Compound SDC-TRAP-0244)
Affinity DataIC50:  100nMAssay Description:HER2 has emerged as a key target for anticancer drugs due to its intrinsic involvement in the phosphatidylinositol-3-kinase-Akt/protein kinase B (PI3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131809(BDBM194684 | US8835464, 11b)
Affinity DataIC50:  100nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131816(US8835464, 18b | US9206162, 18b)
Affinity DataIC50: <100nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131816(US8835464, 18b | US9206162, 18b)
Affinity DataIC50: <100nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131809(BDBM194684 | US8835464, 11b)
Affinity DataIC50: <100nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131818(US8835464, 2d | US9206162, 2d)
Affinity DataIC50:  107nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131818(US8835464, 2d | US9206162, 2d)
Affinity DataIC50:  107nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131808(BDBM194682 | US8835464, 10b)
Affinity DataIC50:  110nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Madrigal Pharmaceuticals

US Patent
LigandPNGBDBM297482(US10117944, Compound SDC-TRAP-0246)
Affinity DataIC50:  110nMAssay Description:HER2 has emerged as a key target for anticancer drugs due to its intrinsic involvement in the phosphatidylinositol-3-kinase-Akt/protein kinase B (PI3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131808(BDBM194682 | US8835464, 10b)
Affinity DataIC50: <110nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131834(US8835464, 20d | US9206162, 20d)
Affinity DataIC50:  114nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131834(US8835464, 20d | US9206162, 20d)
Affinity DataIC50:  114nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Madrigal Pharmaceuticals

US Patent
LigandPNGBDBM297490(US10117944, Compound SDC-TRAP-0245)
Affinity DataIC50:  117nMAssay Description:HER2 has emerged as a key target for anticancer drugs due to its intrinsic involvement in the phosphatidylinositol-3-kinase-Akt/protein kinase B (PI3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131819(US8835464, 3d | US9206162, 3d)
Affinity DataIC50:  180nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131819(US8835464, 3d | US9206162, 3d)
Affinity DataIC50:  180nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM176686(US9120745, 4)
Affinity DataIC50:  182nMT: 2°CAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Synta Pharmaceuticals

US Patent
LigandPNGBDBM131828(US8835464, 12d | US8835464, 13d | US9206162, 13d)
Affinity DataIC50:  207nMAssay Description:Hsp90 protein is obtained from Stressgen (Cat#SPP-770). Assay buffer: 100 mM Tris-HCl, Ph7.4, 20 mM KCl, 6 mM MgCl2. Malachite green (0.0812% w/v) (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
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