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Found 109 with Last Name = 'chen' and Initial = 'xh'
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362153(CHEMBL1940678)
Affinity DataKi:  760nMAssay Description:Binding affinity to Bcl-2 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362141(CHEMBL1940679)
Affinity DataKi:  800nMAssay Description:Binding affinity to Bcl-2 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362147(CHEMBL1940666)
Affinity DataKi:  830nMAssay Description:Binding affinity to Bcl-2 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362152(CHEMBL1940671)
Affinity DataKi:  930nMAssay Description:Binding affinity to Bcl-2 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362150(CHEMBL1940669)
Affinity DataKi:  1.09E+3nMAssay Description:Binding affinity to Bcl-2 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362141(CHEMBL1940679)
Affinity DataKi:  1.27E+3nMAssay Description:Binding affinity to Bcl-xL by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362151(CHEMBL1940670)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity to Bcl-2 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362153(CHEMBL1940678)
Affinity DataKi:  1.50E+3nMAssay Description:Binding affinity to Bcl-xL by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362149(CHEMBL1940668)
Affinity DataKi:  1.67E+3nMAssay Description:Binding affinity to Bcl-2 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362150(CHEMBL1940669)
Affinity DataKi:  1.71E+3nMAssay Description:Binding affinity to Bcl-xL by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362143(CHEMBL1940662)
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity to Mcl-1 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362152(CHEMBL1940671)
Affinity DataKi:  1.94E+3nMAssay Description:Binding affinity to Bcl-xL by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362151(CHEMBL1940670)
Affinity DataKi:  2.08E+3nMAssay Description:Binding affinity to Bcl-xL by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362142(CHEMBL1940680)
Affinity DataKi:  2.29E+3nMAssay Description:Binding affinity to Bcl-xL by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362144(CHEMBL1940663)
Affinity DataKi:  2.29E+3nMAssay Description:Binding affinity to Mcl-1 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362149(CHEMBL1940668)
Affinity DataKi:  2.51E+3nMAssay Description:Binding affinity to Bcl-xL by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362152(CHEMBL1940671)
Affinity DataKi:  2.54E+3nMAssay Description:Binding affinity to Mcl-1 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362150(CHEMBL1940669)
Affinity DataKi:  3.02E+3nMAssay Description:Binding affinity to Mcl-1 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362151(CHEMBL1940670)
Affinity DataKi:  3.09E+3nMAssay Description:Binding affinity to Mcl-1 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362145(CHEMBL1940664)
Affinity DataKi:  3.11E+3nMAssay Description:Binding affinity to Mcl-1 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362146(CHEMBL1940665)
Affinity DataKi:  3.11E+3nMAssay Description:Binding affinity to Mcl-1 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362141(CHEMBL1940679)
Affinity DataKi:  3.11E+3nMAssay Description:Binding affinity to Mcl-1 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362148(CHEMBL1940667)
Affinity DataKi:  3.27E+3nMAssay Description:Binding affinity to Mcl-1 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362144(CHEMBL1940663)
Affinity DataKi:  3.38E+3nMAssay Description:Binding affinity to Bcl-2 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362146(CHEMBL1940665)
Affinity DataKi:  3.39E+3nMAssay Description:Binding affinity to Bcl-2 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362146(CHEMBL1940665)
Affinity DataKi:  3.42E+3nMAssay Description:Binding affinity to Bcl-xL by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362145(CHEMBL1940664)
Affinity DataKi:  3.52E+3nMAssay Description:Binding affinity to Bcl-2 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362143(CHEMBL1940662)
Affinity DataKi:  3.78E+3nMAssay Description:Binding affinity to Bcl-2 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362145(CHEMBL1940664)
Affinity DataKi:  3.91E+3nMAssay Description:Binding affinity to Bcl-xL by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362147(CHEMBL1940666)
Affinity DataKi:  4.03E+3nMAssay Description:Binding affinity to Mcl-1 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362153(CHEMBL1940678)
Affinity DataKi:  4.10E+3nMAssay Description:Binding affinity to Mcl-1 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362149(CHEMBL1940668)
Affinity DataKi:  4.16E+3nMAssay Description:Binding affinity to Mcl-1 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362144(CHEMBL1940663)
Affinity DataKi:  4.84E+3nMAssay Description:Binding affinity to Bcl-xL by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362143(CHEMBL1940662)
Affinity DataKi:  5.82E+3nMAssay Description:Binding affinity to Bcl-xL by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362147(CHEMBL1940666)
Affinity DataKi:  6.45E+3nMAssay Description:Binding affinity to Bcl-xL by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362142(CHEMBL1940680)
Affinity DataKi:  7.22E+3nMAssay Description:Binding affinity to Mcl-1 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362148(CHEMBL1940667)
Affinity DataKi:  9.49E+3nMAssay Description:Binding affinity to Bcl-2 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362142(CHEMBL1940680)
Affinity DataKi:  1.52E+4nMAssay Description:Binding affinity to Bcl-2 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50362148(CHEMBL1940667)
Affinity DataKi:  1.64E+4nMAssay Description:Binding affinity to Bcl-xL by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to Mcl-1 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142796(CHEMBL3759186)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of HDAC1 (unknown origin) preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142796(CHEMBL3759186)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142857(CHEMBL3758839)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142796(CHEMBL3759186)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of HDAC2 (unknown origin) preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142796(CHEMBL3759186)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of HDAC8 (unknown origin) preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142898(CHEMBL3758380)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142845(CHEMBL3759591)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142859(CHEMBL3759261)
Affinity DataIC50:  11nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142838(CHEMBL3758697)
Affinity DataIC50:  12nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  15nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts preincubated for 15 mins followed by addition of Fluor de Lys as substrate for 1 hr by fluorom...More data for this Ligand-Target Pair
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