Found 81 with Last Name = 'li' and Initial = 'xx' TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of CYP46A1 (unknown origin)More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 106nMAssay Description:Inhibition of CYP46A1 (unknown origin)More data for this Ligand-Target Pair
TargetCholesterol 24-hydroxylase(Homo sapiens (Human))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 258nMAssay Description:Inhibition of CYP46A1 (unknown origin)More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Displacement of [125I]Ang2 from AT1 receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Displacement of [125I]Ang2 from AT1 receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation incubated at 37 degC for 16 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Displacement of [125I]Ang2 from AT1 receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Beijing University Of Chinese Medicine
Curated by ChEMBL
Beijing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Displacement of [3H]-5HT from rat SERT expressed in CHO cells incubated for 20 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation incubated at 37 degC for 16 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Displacement of [125I]Ang2 from AT1 receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of [125I]Ang2 from AT1 receptor in bovine adrenal cortexMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 1.59E+3nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 3.49E+3nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 4.46E+3nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
3D Structure (crystal)TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 5.24E+3nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 6.15E+3nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of SARS-CoV-2 MPro incubated for 5 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of SARS-CoV-2 MPro incubated for 5 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation incubated at 37 degC for 16 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of SARS-CoV-2 MPro incubated for 5 mins by FRET assayMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 1.23E+4nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 1.27E+4nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation incubated at 37 degC for 16 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 1.72E+4nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 2.12E+4nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation incubated at 37 degC for 16 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.43E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation incubated at 37 degC for 16 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
Affinity DataIC50: 4.35E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation incubated at 37 degC for 16 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Curated by ChEMBL
Affinity DataIC50: 4.98E+4nMAssay Description:Reversal of P-gp-mediated drug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50...More data for this Ligand-Target Pair
Affinity DataIC50: 7.19E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation incubated at 37 degC for 16 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.59E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation incubated at 37 degC for 16 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
TargetC3a anaphylatoxin chemotactic receptor(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 282nMAssay Description:Agonist activity at human C3aR expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins...More data for this Ligand-Target Pair
TargetC3a anaphylatoxin chemotactic receptor(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 62nMAssay Description:Agonist activity at human C3aR expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins...More data for this Ligand-Target Pair
TargetC3a anaphylatoxin chemotactic receptor(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 11nMAssay Description:Agonist activity at human C3aR expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins...More data for this Ligand-Target Pair
TargetC3a anaphylatoxin chemotactic receptor(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 435nMAssay Description:Agonist activity at human C3aR expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins...More data for this Ligand-Target Pair
TargetC3a anaphylatoxin chemotactic receptor(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 5.48E+4nMAssay Description:Agonist activity at human C3aR expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins...More data for this Ligand-Target Pair
TargetC3a anaphylatoxin chemotactic receptor(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 9nMAssay Description:Agonist activity at human C3aR expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins...More data for this Ligand-Target Pair
TargetC3a anaphylatoxin chemotactic receptor(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 37nMAssay Description:Agonist activity at human C3aR expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins...More data for this Ligand-Target Pair
TargetC3a anaphylatoxin chemotactic receptor(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 7.02E+3nMAssay Description:Agonist activity at human C3aR expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins...More data for this Ligand-Target Pair
TargetC3a anaphylatoxin chemotactic receptor(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 1.31E+5nMAssay Description:Agonist activity at human C3aR expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins...More data for this Ligand-Target Pair
TargetC3a anaphylatoxin chemotactic receptor(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 532nMAssay Description:Agonist activity at human C3aR expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins...More data for this Ligand-Target Pair
TargetC3a anaphylatoxin chemotactic receptor(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human C3aR expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins...More data for this Ligand-Target Pair
TargetC3a anaphylatoxin chemotactic receptor(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 5.51E+4nMAssay Description:Agonist activity at human C3aR expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins...More data for this Ligand-Target Pair
TargetC3a anaphylatoxin chemotactic receptor(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human C3aR expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins...More data for this Ligand-Target Pair
TargetC3a anaphylatoxin chemotactic receptor(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 1.73E+4nMAssay Description:Agonist activity at human C3aR expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins...More data for this Ligand-Target Pair
TargetC3a anaphylatoxin chemotactic receptor(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 3.76E+3nMAssay Description:Agonist activity at human C3aR expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins...More data for this Ligand-Target Pair
TargetC3a anaphylatoxin chemotactic receptor(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataEC50: 2.94E+3nMAssay Description:Agonist activity at human C3aR expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins...More data for this Ligand-Target Pair
