TargetOrnithine aminotransferase, mitochondrial(Homo sapiens (Human))
Hebrew University-Hadassah Medical Center
Curated by ChEMBL
Hebrew University-Hadassah Medical Center
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Inhibition of human recombinant OAT using 1 mM alpha-ketoglutarate as substrateMore data for this Ligand-Target Pair
TargetOrnithine aminotransferase, mitochondrial(Homo sapiens (Human))
Hebrew University-Hadassah Medical Center
Curated by ChEMBL
Hebrew University-Hadassah Medical Center
Curated by ChEMBL
Affinity DataKi: 4.20nMAssay Description:Inhibition of human recombinant OAT using 1 mM alpha-ketoglutarate as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity to 5HT7 receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 23.9nMAssay Description:Displacement of [3H]dofetilide from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 37.2nMAssay Description:Displacement of [3H]dofetilide from human ERG channelMore data for this Ligand-Target Pair
Affinity DataKi: 76nMAssay Description:Binding affinity to adrenergic Alpha-1A receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: >100nMAssay Description:Displacement of [3H]dofetilide from human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: >100nMAssay Description:Displacement of [3H]dofetilide from human ERG channelMore data for this Ligand-Target Pair
Affinity DataKi: 103nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Binding affinity to 5HT2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to beta-1 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to adrenergic alpha-1b receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to beta2 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]DHT from human cloned androgen receptor expressed in insect Sf9 cell systemMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Binding affinity to human androgen receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity at androgen receptor expressed in MDA-MB-453 cells assessed as inhibition of dihydrotestosterone-induced response in reporter gen...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Antagonist activity at androgen receptor expressed in MDA-MB-453 cells assessed as inhibition of dihydrotestosterone-induced response in reporter gen...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Displacement of [3H]DHT from human cloned androgen receptor expressed in insect Sf9 cell systemMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Binding affinity to human androgen receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Binding affinity to human androgen receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]DHT from human cloned androgen receptor expressed in insect Sf9 cell systemMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human androgen receptor expressed in human MDA-MB-231 cells assessed as inhibition of DHT-induced responseMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Binding affinity to human androgen receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Displacement of [3H]DHT from human cloned androgen receptor expressed in insect Sf9 cell systemMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Binding affinity to human androgen receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Antagonist activity at human androgen receptor by cell based assayMore data for this Ligand-Target Pair