Affinity DataKi: 0.00500nMAssay Description:Inhibition against Opioid receptor mu 1 using [3H]- DAMGO radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Inhibition against Opioid receptor mu 1 using [3H]- DAMGO radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Inhibition against Opioid receptor mu 1 using [3H]- DAMGO radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Inhibition against Opioid receptor mu 1 using [3H]- DAMGO radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Inhibition against Opioid receptor mu 1 using [3H]- DAMGO radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Inhibition against Opioid receptor mu 1 using [3H]- DAMGO radioligand.More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National Medicines Institute
Curated by ChEMBL
National Medicines Institute
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]-5HT from human SERTMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Inhibitory affinity constant against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nM ΔG°: -49.9kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
Affinity DataKi: 2.89nMAssay Description:Inhibition against Opioid receptor mu 1 using [3H]- DAMGO radioligand.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 3.10nMAssay Description:Displacement of bound [3H]-diprenorphine in cloned rat Opioid receptor kappa 1 expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:Inhibitory affinity constant against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nM ΔG°: -47.6kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 5.70nMAssay Description:Displacement of bound [3H]-diprenorphine in cloned rat Opioid receptor kappa 1 expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.85nMAssay Description:Inhibition against Opioid receptor mu 1 using [3H]- DAMGO radioligand.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Polish Academy Of Sciences
Curated by ChEMBL
Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Binding affinity at 5HT1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibitory affinity constant against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Polish Academy Of Sciences
Curated by ChEMBL
Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
Affinity DataKi: 12.6nM ΔG°: -45.1kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Polish Academy Of Sciences
Curated by ChEMBL
Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibitory affinity constant against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Polish Academy Of Sciences
Curated by ChEMBL
Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Yaroslavl State Technical University
Curated by ChEMBL
Yaroslavl State Technical University
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Inhibition of human recombinant MAO-B assessed as kynuramine substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 16.1nM ΔG°: -44.5kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Yaroslavl State Technical University
Curated by ChEMBL
Yaroslavl State Technical University
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Inhibition of human recombinant MAO-A assessed as kynuramine substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 20.8nM ΔG°: -43.8kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Polish Academy Of Sciences
Curated by ChEMBL
Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
Affinity DataKi: 24nM ΔG°: -43.5kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
National Medicines Institute
Curated by ChEMBL
National Medicines Institute
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Displacement of [3H]-5HT from human SERTMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Polish Academy Of Sciences
Curated by ChEMBL
Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 36nMAssay Description:Binding affinity at 5HT1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Polish Academy Of Sciences
Curated by ChEMBL
Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Yaroslavl State Technical University
Curated by ChEMBL
Yaroslavl State Technical University
Curated by ChEMBL
Affinity DataKi: 38nMAssay Description:Competitive inhibition of human MAOB expressed in insect cell microsomes using varying levels of kynuramine as substrate measured after 20 mins by Li...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Polish Academy Of Sciences
Curated by ChEMBL
Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 39nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Polish Academy Of Sciences
Curated by ChEMBL
Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 39nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 39nMAssay Description:Inhibitory affinity constant against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 54.1nM ΔG°: -41.5kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
Affinity DataKi: 72.9nM ΔG°: -40.7kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
Affinity DataKi: 80.5nM ΔG°: -40.5kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
Affinity DataKi: 86.1nM ΔG°: -40.3kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
Affinity DataKi: 114nMAssay Description:Inhibition against delta-opioid receptor using [3H]-DPDPE radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Inhibition against Opioid receptor delta 1 using [3H]-DPDPE radioligand.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Polish Academy Of Sciences
Curated by ChEMBL
Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 197nMAssay Description:Displacement of [3H]5CT from 5HT7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Inhibition against delta-opioid receptor using [3H]-DPDPE radioligand.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Polish Academy Of Sciences
Curated by ChEMBL
Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 221nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Polish Academy Of Sciences
Curated by ChEMBL
Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Inhibition against delta-opioid receptor using [3H]-DPDPE radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Inhibition against delta-opioid receptor using [3H]-DPDPE radioligand.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Polish Academy Of Sciences
Curated by ChEMBL
Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 265nMAssay Description:Displacement of [3H]5CT from 5HT7 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Polish Academy Of Sciences
Curated by ChEMBL
Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 275nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
Affinity DataKi: 496nM ΔG°: -36.0kJ/molepH: 7.7 T: 2°CAssay Description:The assay was performed in accordance with the method described by Owens et al. with slight modifications. Rat cerebral cortex was homogenized in 30...More data for this Ligand-Target Pair
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