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Found 1463 with Last Name = 'ahn' and Initial = 'sk'
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM250432(US9464044, 22)
Affinity DataIC50:  0.0200nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112149(CHEMBL3609877)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM250460(US9464044, 62)
Affinity DataIC50:  0.120nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112154(CHEMBL3608403)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112151(CHEMBL3608400)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM250418(US9464044, 8)
Affinity DataIC50:  0.300nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112152(CHEMBL3608401 | US9464044, 84)
Affinity DataIC50:  0.360nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM250453(US9464044, 50)
Affinity DataIC50:  0.400nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112152(CHEMBL3608401 | US9464044, 84)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112133(CHEMBL3609861 | US9464044, 71)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50304788(CHEMBL594160 | methyl 4-(3-chloro-4-methoxybenzyla...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of bovine platelet PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112133(CHEMBL3609861 | US9464044, 71)
Affinity DataIC50:  0.600nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112143(CHEMBL3609871 | US9464044, 73)
Affinity DataIC50:  0.830nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM250486(US9464044, 119)
Affinity DataIC50:  0.900nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112143(CHEMBL3609871 | US9464044, 73)
Affinity DataIC50:  1nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50246252(CHEMBL521075 | N-(4-(3-chloro-4-methoxybenzylamino...)
Affinity DataIC50:  1nMAssay Description:Inhibition of bovine PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50246252(CHEMBL521075 | N-(4-(3-chloro-4-methoxybenzylamino...)
Affinity DataIC50:  1nMAssay Description:Inhibition of bovine platelet PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50304789(CHEMBL604271 | N-(4-(3-chloro-4-methoxybenzylamino...)
Affinity DataIC50:  1nMAssay Description:Inhibition of bovine platelet PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50304790(CHEMBL595330 | N-(4-(3-chloro-4-methoxybenzylamino...)
Affinity DataIC50:  1nMAssay Description:Inhibition of bovine platelet PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50304792(CHEMBL595104 | N-(4-(3-chloro-4-methoxybenzylamino...)
Affinity DataIC50:  1nMAssay Description:Inhibition of bovine platelet PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50448221(CHEMBL3120828)
Affinity DataIC50:  1nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50448224(CHEMBL3120825)
Affinity DataIC50:  1nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50448225(CHEMBL3120824)
Affinity DataIC50:  1nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50448229(CHEMBL3120820)
Affinity DataIC50:  1nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50448230(CHEMBL3120819)
Affinity DataIC50:  1nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50448231(CHEMBL3120818)
Affinity DataIC50:  1nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50448232(CHEMBL3120817)
Affinity DataIC50:  1nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50448235(CHEMBL3120758)
Affinity DataIC50:  1nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117677(US8653087, III-357 | US8653087, III-364)
Affinity DataIC50: <1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117685(US8653087, III-365)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117690(US8653087, III-370)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117702(US8653087, III-382)
Affinity DataIC50: <1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117706(US8653087, III-386)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117708(US8653087, III-388)
Affinity DataIC50: <1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117709(US8653087, III-389)
Affinity DataIC50: <1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117710(US8653087, III-390)
Affinity DataIC50: <1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117711(US8653087, III-391)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117713(US8653087, III-393)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117714(US8653087, III-394)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117718(US8653087, III-398)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117730(US8653087, III-410)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117733(US8653087, III-413)
Affinity DataIC50: <1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117736(US8653087, III-416)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117737(US8653087, III-417)
Affinity DataIC50: <1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117739(US8653087, III-419 | US8653087, III-562)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117740(US8653087, III-420)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117743(US8653087, III-423)
Affinity DataIC50: <1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117746(US8653087, III-426)
Affinity DataIC50: <1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117748(US8653087, III-428)
Affinity DataIC50: <1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117563(US8653087, III-243)
Affinity DataIC50: <1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
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