Found 1659 with Last Name = 'ahn' and Initial = 'y' TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetAsparagine synthetase [glutamine-hydrolyzing](Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant ASNS expressed in Sf9 cells assessed as assessed as overall inhibition constant for ammonia dependent production of i...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 3.10nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 5.90nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of RTX-induced 45Ca2+ uptake after 20 mins by liquid scintillation c...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 6.10nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 6.60nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.90nMAssay Description:Competitive inhibition of recombinant human MAO-B using varying level of benzylamine substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetAsparagine synthetase [glutamine-hydrolyzing](Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant ASNS expressed in Sf9 cells assessed as overall inhibition constant for glutamine dependent production of inorganic p...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetAsparagine synthetase [glutamine-hydrolyzing](Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of human recombinant ASNS expressed in Sf9 cells assessed as overall inhibition constant for glutamine dependent production of inorganic p...More data for this Ligand-Target Pair
TargetAsparagine synthetase [glutamine-hydrolyzing](Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Inhibition of human recombinant ASNS expressed in Sf9 cells assessed as assessed as overall inhibition constant for ammonia dependent production of i...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 63nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cells after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Binding affinity to human XIAP-BIR3 (241 to 356 residues)More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 94nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of RTX-induced 45Ca2+ uptake after 20 mins by liquid scintillation c...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 122nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of RTX-induced 45Ca2+ uptake after 20 mins by liquid scintillation c...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 161nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of RTX-induced 45Ca2+ uptake after 20 mins by liquid scintillation c...More data for this Ligand-Target Pair
TargetAsparagine synthetase [glutamine-hydrolyzing](Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataKi: 280nMAssay Description:Inhibition of human recombinant ASNS expressed in Sf9 cells assessed as assessed as initial inhibition constant for ammonia dependent production of i...More data for this Ligand-Target Pair
TargetAsparagine synthetase [glutamine-hydrolyzing](Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataKi: 310nMAssay Description:Inhibition of human recombinant ASNS expressed in Sf9 cells assessed as assessed as overall inhibition constant for ammonia dependent production of i...More data for this Ligand-Target Pair
TargetAsparagine synthetase [glutamine-hydrolyzing](Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataKi: 450nMAssay Description:Inhibition of human recombinant ASNS expressed in Sf9 cells assessed as assessed as initial inhibition constant for ammonia dependent production of i...More data for this Ligand-Target Pair
TargetAsparagine synthetase [glutamine-hydrolyzing](Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataKi: 490nMAssay Description:Inhibition of human recombinant ASNS expressed in Sf9 cells assessed as initial inhibition constant for glutamine dependent production of inorganic p...More data for this Ligand-Target Pair
TargetAsparagine synthetase [glutamine-hydrolyzing](Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataKi: 840nMAssay Description:Inhibition of human recombinant ASNS expressed in Sf9 cells assessed as overall inhibition constant for glutamine dependent production of inorganic p...More data for this Ligand-Target Pair
TargetAsparagine synthetase [glutamine-hydrolyzing](Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of human recombinant ASNS expressed in Sf9 cells assessed as initial inhibition constant for glutamine dependent production of inorganic p...More data for this Ligand-Target Pair
TargetAsparagine synthetase [glutamine-hydrolyzing](Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataKi: 3.04E+3nMAssay Description:Inhibition of human recombinant ASNS expressed in Sf9 cells assessed as assessed as initial inhibition constant for ammonia dependent production of i...More data for this Ligand-Target Pair
TargetAsparagine synthetase [glutamine-hydrolyzing](Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataKi: 4.50E+3nMAssay Description:Inhibition of human recombinant ASNS expressed in Sf9 cells assessed as initial inhibition constant for glutamine dependent production of inorganic p...More data for this Ligand-Target Pair
Affinity DataKi: 2.04E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.14E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.92E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.75E+4nMAssay Description:Binding affinity to Cdc25A (336-523) (unknown origin) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:The inhibitory activity of the synthesized compounds above against EZH1 or EZH2 methyltransferase was measured. The experiments were consigned to Rea...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.360nMAssay Description:The inhibitory activity of the synthesized compounds above against EZH1 or EZH2 methyltransferase was measured. The experiments were consigned to Rea...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.400nMAssay Description:The inhibitory activity of some of the compounds described above against FLT3-ITD, FLT3 wild type (WT), VEGFR2 (KDR), and SYK kinase was measured. Th...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:The inhibitory activity of some of the compounds described above against FLT3-ITD, FLT3 wild type (WT), VEGFR2 (KDR), and SYK kinase was measured. Th...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:The inhibitory activity of some of the compounds described above against FLT3-ITD, FLT3 wild type (WT), VEGFR2 (KDR), and SYK kinase was measured.The...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:The inhibitory activity of some of the compounds described above against FLT3-ITD, FLT3 wild type (WT), VEGFR2 (KDR), and SYK kinase was measured.The...More data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
TargetDimer of Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Hanmi Pharm.
US Patent
Hanmi Pharm.
US Patent
Affinity DataIC50: 0.5nMAssay Description:The inhibitory activity of some of the compounds described above against FLT3-ITD, FLT3 wild type (WT), VEGFR2 (KDR), and SYK kinase was measured.The...More data for this Ligand-Target Pair
TargetDimer of Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Hanmi Pharm.
US Patent
Hanmi Pharm.
US Patent
Affinity DataIC50: 0.5nMAssay Description:The inhibitory activity of some of the compounds described above against FLT3-ITD, FLT3 wild type (WT), VEGFR2 (KDR), and SYK kinase was measured. Th...More data for this Ligand-Target Pair
Affinity DataIC50: 0.590nMAssay Description:The inhibitory activity of the synthesized compounds above against EZH1 or EZH2 methyltransferase was measured. The experiments were consigned to Rea...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant BRAF V600E mutant (unknown origin) assessed as ADP formation measured for 5 hrs by pyruvate kinase/lactate dehydrogenase co...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:As such, the compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profili...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:The inhibitory activity of some of the compounds described above against FLT3-ITD, FLT3 wild type (WT), VEGFR2 (KDR), and SYK kinase was measured. Th...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:The inhibitory activity of some of the compounds described above against FLT3-ITD, FLT3 wild type (WT), VEGFR2 (KDR), and SYK kinase was measured.The...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of wild type CRAF (unknown origin) assessed as ADP formation measured for 5 hrs by pyruvate kinase/lactate dehydrogenase coupled assay in ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant BRAF V600E mutant (unknown origin) assessed as ADP formation measured for 5 hrs by pyruvate kinase/lactate dehydrogenase co...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:The inhibitory activity of some of the compounds described above against FLT3-ITD, FLT3 wild type (WT), VEGFR2 (KDR), and SYK kinase was measured. Th...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:The inhibitory activity of some of the compounds described above against FLT3-ITD, FLT3 wild type (WT), VEGFR2 (KDR), and SYK kinase was measured.The...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:The inhibitory activity of the synthesized compounds above against EZH1 or EZH2 methyltransferase was measured. The experiments were consigned to Rea...More data for this Ligand-Target Pair
Ligand Info
