Affinity DataIC50: 0.0930nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in bovine cerebrum membrane for Endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in bovine cerebrum membrane for Endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in porcine cardiac ventricular membrane for Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in bovine cerebrum membrane for Endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in bovine cerebrum membrane for Endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.180nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in porcine cardiac ventricular membrane for Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.190nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in porcine cardiac ventricular membrane for Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in porcine cardiac ventricular membrane for Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in bovine cerebrum membrane for Endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.330nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in bovine cerebrum membrane for Endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in porcine cardiac ventricular membrane for Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in bovine cerebrum membrane for Endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.450nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in bovine cerebrum membrane for Endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in porcine cardiac ventricular membrane for Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in porcine cardiac ventricular membrane for Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.75nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in porcine cardiac ventricular membrane for Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in porcine cardiac ventricular membrane for Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 8.60nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in porcine cardiac ventricular membrane for Endothelin A receptorMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in rat plateletMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in rat whole bloodMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in rat plateletMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in human plateletMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in human plateletMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in human plateletMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 760nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 840nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in human whole bloodMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in rat plateletMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in human microsomeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in human microsomeMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in rat whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Tested in vitro against TXA2 synthetase inhibitory activity in human whole bloodMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:In vitro inhibition of K+ induced contractions of the isolated rat aorta.More data for this Ligand-Target Pair