Affinity DataIC50: 5.20nMAssay Description:Inhibition of horse serum BChE using butrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured for 10 min...More data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMpH: 8.0 T: 2°CAssay Description:This spectrophotometric assay is based on the reaction of
5,5-dithio-bis(2-nitrobenzoic)acid (DTNB) with thiocholine to yield a
colored product. Sh...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology
Curated by ChEMBL
Wuhan University of Technology
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (unknown origin) (645 to 1186 residues) expressed in baculovirus infected Sf-9 cells pr...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology
Curated by ChEMBL
Wuhan University of Technology
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (unknown origin) (645 to 1186 residues) expressed in baculovirus infected Sf-9 cells pr...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMpH: 8.0 T: 2°CAssay Description:This spectrophotometric assay is based on the reaction of
5,5-dithio-bis(2-nitrobenzoic)acid (DTNB) with thiocholine to yield a
colored product. Sh...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured for 10 mi...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology
Curated by ChEMBL
Wuhan University of Technology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (unknown origin) (645 to 1186 residues) expressed in baculovirus infected Sf-9 cells pr...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of AChE (unknown origin) after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMpH: 8.0 T: 2°CAssay Description:This spectrophotometric assay is based on the reaction of
5,5-dithio-bis(2-nitrobenzoic)acid (DTNB) with thiocholine to yield a
colored product. Sh...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMpH: 7.4 T: 2°CAssay Description:A fluorimetric method reported by Matsumoto et al.[T. Matsumoto, O. Suzuki, T. Furuta, M. Asai, Y. Kurokawa, Y. Nimura, Y. Katsumata, I. Takahashi. C...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology
Curated by ChEMBL
Wuhan University of Technology
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant 6His-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
Ligand Info
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology
Curated by ChEMBL
Wuhan University of Technology
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant 6His-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of AChE (unknown origin) after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 59nMpH: 8.0 T: 2°CAssay Description:This spectrophotometric assay is based on the reaction of
5,5-dithio-bis(2-nitrobenzoic)acid (DTNB) with thiocholine to yield a
colored product. Sh...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology
Curated by ChEMBL
Wuhan University of Technology
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (unknown origin) (645 to 1186 residues) expressed in baculovirus infected Sf-9 cells pr...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology
Curated by ChEMBL
Wuhan University of Technology
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (unknown origin) (645 to 1186 residues) expressed in baculovirus infected Sf-9 cells pr...More data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of AChE (unknown origin) after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology
Curated by ChEMBL
Wuhan University of Technology
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant 6His-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 120nMpH: 7.4 T: 2°CAssay Description:A fluorimetric method reported by Matsumoto et al.[T. Matsumoto, O. Suzuki, T. Furuta, M. Asai, Y. Kurokawa, Y. Nimura, Y. Katsumata, I. Takahashi. C...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMpH: 8.0 T: 2°CAssay Description:This spectrophotometric assay is based on the reaction of
5,5-dithio-bis(2-nitrobenzoic)acid (DTNB) with thiocholine to yield a
colored product. Sh...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of ovine COX1 using arachidonic acid substrate assessed as PGE2 production ELISA method after 2 minsMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Affinity DataIC50: 220nMpH: 8.0 T: 2°CAssay Description:100 mM Tris¿HCl buffer, pH 8.0 containing 1 µM heme and COX-1 (ovine) or COX-2(human recombinant), which was preincubated for 10 min in a water bath ...More data for this Ligand-Target Pair
Affinity DataIC50: 270nMpH: 8.0 T: 2°CAssay Description:This spectrophotometric assay is based on the reaction of
5,5-dithio-bis(2-nitrobenzoic)acid (DTNB) with thiocholine to yield a
colored product. Sh...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of ovine COX1 using arachidonic acid substrate assessed as PGE2 production ELISA method after 2 minsMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of ovine COX1 using arachidonic acid substrate assessed as PGE2 production ELISA method after 2 minsMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Affinity DataIC50: 440nMpH: 8.0 T: 2°CAssay Description:100 mM Tris¿HCl buffer, pH 8.0 containing 1 µM heme and COX-1 (ovine) or COX-2(human recombinant), which was preincubated for 10 min in a water bath ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Inhibition of ovine COX1 using arachidonic acid substrate assessed as PGE2 production ELISA method after 2 minsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology
Curated by ChEMBL
Wuhan University of Technology
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant 6His-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 510nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 570nMpH: 8.0 T: 2°CAssay Description:This spectrophotometric assay is based on the reaction of
5,5-dithio-bis(2-nitrobenzoic)acid (DTNB) with thiocholine to yield a
colored product. Sh...More data for this Ligand-Target Pair
TargetPhospholipase A2 group V(Homo sapiens (Human))
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz
Affinity DataIC50: 620nMpH: 7.5 T: 2°CAssay Description:Briefly, sn-2ester bond of the substrate 1,2-bis(heptanoylthio)-glycerophosphocholine was hydrolyzed by PLA2-V followed by the exposure of free thiol...More data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured for 10 mi...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of ovine COX1 using arachidonic acid substrate assessed as PGE2 production ELISA method after 2 minsMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of ovine COX1 using arachidonic acid substrate assessed as PGE2 production ELISA method after 2 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 880nMAssay Description:Inhibition of AChE (unknown origin) after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 880nMpH: 7.4 T: 2°CAssay Description:A fluorimetric method reported by Matsumoto et al.[T. Matsumoto, O. Suzuki, T. Furuta, M. Asai, Y. Kurokawa, Y. Nimura, Y. Katsumata, I. Takahashi. C...More data for this Ligand-Target Pair
Affinity DataIC50: 910nMpH: 7.4 T: 2°CAssay Description:A fluorimetric method reported by Matsumoto et al.[T. Matsumoto, O. Suzuki, T. Furuta, M. Asai, Y. Kurokawa, Y. Nimura, Y. Katsumata, I. Takahashi. C...More data for this Ligand-Target Pair
Affinity DataIC50: 920nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 920nMpH: 7.4 T: 2°CAssay Description:A fluorimetric method reported by Matsumoto et al.[T. Matsumoto, O. Suzuki, T. Furuta, M. Asai, Y. Kurokawa, Y. Nimura, Y. Katsumata, I. Takahashi. C...More data for this Ligand-Target Pair
Affinity DataIC50: 920nMAssay Description:Inhibition of AChE (unknown origin) after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Affinity DataIC50: 940nMpH: 8.0 T: 2°CAssay Description:100 mM Tris¿HCl buffer, pH 8.0 containing 1 µM heme and COX-1 (ovine) or COX-2(human recombinant), which was preincubated for 10 min in a water bath ...More data for this Ligand-Target Pair
Affinity DataIC50: 990nMpH: 7.4 T: 2°CAssay Description:A fluorimetric method reported by Matsumoto et al.[T. Matsumoto, O. Suzuki, T. Furuta, M. Asai, Y. Kurokawa, Y. Nimura, Y. Katsumata, I. Takahashi. C...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Affinity DataIC50: 990nMAssay Description:Inhibition of ovine COX1 using arachidonic acid substrate assessed as PGE2 production ELISA method after 2 minsMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Affinity DataIC50: 990nMpH: 8.0 T: 2°CAssay Description:100 mM Tris¿HCl buffer, pH 8.0 containing 1 µM heme and COX-1 (ovine) or COX-2(human recombinant), which was preincubated for 10 min in a water bath ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FAK (unknown origin) assembly preincubated with enzyme followed by GTP addition measured after 20 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology
Curated by ChEMBL
Wuhan University of Technology
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (unknown origin) (645 to 1186 residues) expressed in baculovirus infected Sf-9 cells pr...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Affinity DataIC50: 1.12E+3nMpH: 8.0 T: 2°CAssay Description:100 mM Tris¿HCl buffer, pH 8.0 containing 1 µM heme and COX-1 (ovine) or COX-2(human recombinant), which was preincubated for 10 min in a water bath ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Universiti Kebangsaan Malaysia
Curated by ChEMBL
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid substrate assessed as PGE2 production ELISA method after 2 minsMore data for this Ligand-Target Pair