Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataKi: 0.0600nMAssay Description:Inhibition of recombinant human C-terminal 6xHis-tagged 15-PGDH expressed in Escherichia coli using PGE2 as substrate after 15 mins in presence of NA...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Binding affinity to 15-PGDH (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Inhibition of 15-PGDH (unknown origin) using PGE2 as substrate preincubated for 12 hrs followed by dialysis for 12 hrs and subsequent addition of NAD...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.360nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (5 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.440nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.450nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.480nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.520nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.520nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.550nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.560nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.560nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.570nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.580nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.590nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.590nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.650nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.720nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.720nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.730nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.75nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.760nMAssay Description:In vivo assays for 15-PGDH expression or 15-PGDH activity, e.g., ligands, agonists, antagonists, and their homologs and mimetics. The term modulator ...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.760nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (5 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.760nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.760nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.770nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.820nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.880nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.910nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.930nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.970nMAssay Description:In vivo assays for 15-PGDH expression or 15-PGDH activity, e.g., ligands, agonists, antagonists, and their homologs and mimetics. The term modulator ...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.970nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay. More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.970nMAssay Description:This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.980nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human C-terminal 6xHis-tagged 15-PGDH expressed in Escherichia coli using PGE2 as substrate after 15 mins in presence of NA...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human C-terminal 6xHis-tagged 15-PGDH expressed in Escherichia coli using PGE2 as substrate after 15 mins in presence of NA...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH (1 nM) in an in vitro assay.More data for this Ligand-Target Pair
Ligand Info