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Found 148 with Last Name = 'atta-ur-rahman' and Initial = 'a'
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University of Karachi

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataKi:  25nM ΔG°:  -44.1kJ/moleT: 2°CAssay Description:AChE and BChE inhibitory activities were measured in vitro by a modified spectrophotometric method. all the inhibition studies were performed using ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
University of Karachi

LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataKi:  190nM ΔG°:  -39.0kJ/moleT: 2°CAssay Description:AChE and BChE inhibitory activities were measured in vitro by a modified spectrophotometric method. all the inhibition studies were performed using ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
University of Karachi

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataKi:  230nM ΔG°:  -38.5kJ/moleT: 2°CAssay Description:AChE and BChE inhibitory activities were measured in vitro by a modified spectrophotometric method. all the inhibition studies were performed using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50512776(CHEMBL4471134)
Affinity DataKi:  2.40E+3nMAssay Description:Uncompetitive inhibition of electric eel BChE using varying levels of butyrylcholine chloride as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50512782(CHEMBL4462721)
Affinity DataKi:  2.60E+3nMAssay Description:Mixed inhibition of equine serum BChE using varying levels of butyrylcholine chloride as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50512783(CHEMBL4536564)
Affinity DataKi:  4.40E+3nMAssay Description:Mixed inhibition of equine serum BChE using varying levels of butyrylcholine chloride as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50512784(CHEMBL4579999)
Affinity DataKi:  5.60E+3nMAssay Description:Uncompetitive inhibition of electric eel BChE using varying levels of butyrylcholine chloride as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50512778(CHEMBL4542735)
Affinity DataKi:  9.90E+3nMAssay Description:Mixed inhibition of equine serum BChE using varying levels of butyrylcholine chloride as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50512777(CHEMBL4470521)
Affinity DataKi:  1.30E+4nMAssay Description:Mixed inhibition of equine serum BChE using varying levels of butyrylcholine chloride as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50512781(CHEMBL4555516)
Affinity DataKi:  1.80E+4nMAssay Description:Mixed inhibition of equine serum BChE using varying levels of butyrylcholine chloride as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University of Karachi

LigandPNGBDBM86023(Methyl isoplatydesmine, 4)
Affinity DataKi:  1.90E+4nM ΔG°:  -27.4kJ/moleT: 2°CAssay Description:AChE and BChE inhibitory activities were measured in vitro by a modified spectrophotometric method. all the inhibition studies were performed using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataKi:  2.15E+4nMAssay Description:Mixed inhibition of equine serum BChE using varying levels of butyrylcholine chloride as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50512780(CHEMBL4513971)
Affinity DataKi:  2.35E+4nMAssay Description:Uncompetitive inhibition of electric eel BChE using varying levels of butyrylcholine chloride as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50512775(CHEMBL4529136)
Affinity DataKi:  2.76E+4nMAssay Description:Uncompetitive inhibition of electric eel BChE using varying levels of butyrylcholine chloride as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
University of Karachi

LigandPNGBDBM86022(Ribalinine, 3)
Affinity DataKi:  3.00E+4nM ΔG°:  -26.2kJ/moleT: 2°CAssay Description:AChE and BChE inhibitory activities were measured in vitro by a modified spectrophotometric method. all the inhibition studies were performed using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
University of Karachi

LigandPNGBDBM86023(Methyl isoplatydesmine, 4)
Affinity DataKi:  3.00E+4nM ΔG°:  -26.2kJ/moleT: 2°CAssay Description:AChE and BChE inhibitory activities were measured in vitro by a modified spectrophotometric method. all the inhibition studies were performed using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University of Karachi

LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataKi:  3.20E+4nM ΔG°:  -26.1kJ/moleT: 2°CAssay Description:AChE and BChE inhibitory activities were measured in vitro by a modified spectrophotometric method. all the inhibition studies were performed using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM86010(Chalcone, 10)
Affinity DataKi:  5.76E+4nM ΔG°:  -24.2kJ/molepH: 8.0 T: 2°CAssay Description:In vitro lipoxygenase inhibition assay, lipoxygenase inhibiting activity was convenintly measured by slightly modifying the spectrometic method devel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University of Karachi

LigandPNGBDBM86022(Ribalinine, 3)
Affinity DataKi:  7.00E+4nM ΔG°:  -24.1kJ/moleT: 2°CAssay Description:AChE and BChE inhibitory activities were measured in vitro by a modified spectrophotometric method. all the inhibition studies were performed using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Quaid-I-Azam University

LigandPNGBDBM86012(Chalcone, 11)
Affinity DataKi:  7.17E+4nM ΔG°:  -23.7kJ/molepH: 8.0 T: 2°CAssay Description:In vitro lipoxygenase inhibition assay, lipoxygenase inhibiting activity was convenintly measured by slightly modifying the spectrometic method devel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University of Karachi

LigandPNGBDBM86021(2,2,6-Trimethyl-3,4,5,6-tetrahydro-2H-pyrano[3,2-c...)
Affinity DataKi:  9.00E+4nM ΔG°:  -23.5kJ/moleT: 2°CAssay Description:AChE and BChE inhibitory activities were measured in vitro by a modified spectrophotometric method. all the inhibition studies were performed using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
University of Karachi

LigandPNGBDBM86021(2,2,6-Trimethyl-3,4,5,6-tetrahydro-2H-pyrano[3,2-c...)
Affinity DataKi:  1.10E+5nM ΔG°:  -23.0kJ/moleT: 2°CAssay Description:AChE and BChE inhibitory activities were measured in vitro by a modified spectrophotometric method. all the inhibition studies were performed using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  41nMAssay Description:Inhibition of electric eel AChE by modified Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  41nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  250nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate after 10 mins by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50259930(6-(10'Z-heptadecenyl)-salicylicacid | 6-[10'(Z)-he...)
Affinity DataIC50:  573nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate after 10 mins by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50512782(CHEMBL4462721)
Affinity DataIC50:  800nMAssay Description:Inhibition of equine serum BChE using butyrylcholine chloride as substrate preincubated for 15 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  857nMAssay Description:Inhibition of BChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  857nMAssay Description:Inhibition of horse BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50512776(CHEMBL4471134)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of equine serum BChE using butyrylcholine chloride as substrate preincubated for 15 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50512783(CHEMBL4536564)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of equine serum BChE using butyrylcholine chloride as substrate preincubated for 15 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University of Karachi

LigandPNGBDBM50218211(1'-(4-Methyl-benzyl)-[1,4']bipiperidinyl | CHEMBL3...)
Affinity DataIC50:  1.72E+3nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50292424(Anacardic acid 10'Z-monoene | CHEMBL470264)
Affinity DataIC50:  2.17E+3nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate after 10 mins by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50259880(3alpha-acetoxy-27-hydroxylup-20(29)-en-24-oic acid...)
Affinity DataIC50:  2.87E+3nMAssay Description:Inhibition of prolyl endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50347127(CHEMBL1797234)
Affinity DataIC50:  3.18E+3nMAssay Description:Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate after 10 mins by Ellman's spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataIC50:  3.25E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University of Karachi

LigandPNGBDBM50198715((2S)-2-amino-3-(3-hydroxy-4-oxopyridin-1(4H)-yl)pr...)
Affinity DataIC50:  3.68E+3nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50512777(CHEMBL4470521)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of equine serum BChE using butyrylcholine chloride as substrate preincubated for 15 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50512774(CHEMBL4448967)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of equine serum BChE using butyrylcholine chloride as substrate preincubated for 15 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University of Karachi

LigandPNGBDBM50218209(CHEMBL250773 | Tyrosinase Inhibitor, 3 | naphthale...)
Affinity DataIC50:  6.64E+3nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM35440(ALLOPURINOL | MLS000069453 | SMR000059083 | cid_20...)
Affinity DataIC50:  7.45E+3nMAssay Description:Inhibition of xanthine oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50241262((3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bS)-3-a...)
Affinity DataIC50:  7.89E+3nMAssay Description:Inhibition of prolyl endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of equine serum BChE using butyrylcholine chloride as substrate preincubated for 15 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of horse serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University of Karachi

LigandPNGBDBM85773(Tyrosinase Inhibitor, 8)
Affinity DataIC50:  8.76E+3nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50241260((3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-3-h...)
Affinity DataIC50:  9.75E+3nMAssay Description:Inhibition of prolyl endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50242345(CHEMBL460447 | [(20S)-20-(N,N-dimethylamino)-3 bet...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of horse BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50241737((1R,4R,5R,9S,11S)-4,5-epoxycaryophyllan-8(13)-en-1...)
Affinity DataIC50:  1.09E+4nMAssay Description:Inhibition of horse serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50512781(CHEMBL4555516)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of equine serum BChE using butyrylcholine chloride as substrate preincubated for 15 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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