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Found 1159 with Last Name = 'ballentine' and Initial = 's'
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50312651(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50312653(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50312652(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50312663(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  6.80nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182163(4-[7-bromo-1-(2,5-difluoro-benzyl)-1H-benzoimidazo...)
Affinity DataKi:  10nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50312658(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  11nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50312662(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  12nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50312654(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  13nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233679(CHEMBL399284 | N-[3'-(5-carbamimidoyl-2-methylsulf...)
Affinity DataKi:  14nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50312656(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  15nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233691(4-(2'-amino-6'-methyl-biphenyl-3-sulfonyl)-5-methy...)
Affinity DataKi:  20nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182160(4-[7-bromo-1-(2,6-dichloro-benzyl)-1H-benzoimidazo...)
Affinity DataKi:  20nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233674(6-{3-[3'-(5-carbamimidoyl-2-methylsulfanyl-thiophe...)
Affinity DataKi:  22nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182170(4-[7-bromo-1-(2-fluoro-5-nitro-benzyl)-1H-benzoimi...)
Affinity DataKi:  30nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182171(4-(1-benzyl-7-bromo-1H-benzoimidazole-5-sulfonyl)-...)
Affinity DataKi:  30nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233686(4-(2'-methyl-biphenyl-3-sulfonyl)-5-methylsulfanyl...)
Affinity DataKi:  30nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50312664(1-{N-[2-(Amidino-N0-methylaminooxy)ethyl]amino}car...)
Affinity DataKi:  37nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182159(4-[7-bromo-1-(2,6-difluoro-benzyl)-1H-benzoimidazo...)
Affinity DataKi:  40nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233692(4-[3-(6-methyl-pyridin-2-yl)-benzenesulfonyl]-5-me...)
Affinity DataKi:  40nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233688(4-(2'-chloro-biphenyl-3-sulfonyl)-5-methylsulfanyl...)
Affinity DataKi:  40nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233694(5-[3'-(5-carbamimidoyl-2-methylsulfanyl-thiophene-...)
Affinity DataKi:  42nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50312661(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  44nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50312655(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  47nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50312657(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  47nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233677(4-(2'-hydroxymethyl-6'-methyl-biphenyl-3-sulfonyl)...)
Affinity DataKi:  50nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182176(4-[7-bromo-1-(3-methyl-but-2-enyl)-1H-benzoimidazo...)
Affinity DataKi:  50nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233689(5-methylsulfanyl-4-(6'-methyl-2'-{3-[2-(2H-tetrazo...)
Affinity DataKi:  64nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50312660(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  66nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182185(4-(1-allyl-7-bromo-1H-benzoimidazole-5-sulfonyl)-5...)
Affinity DataKi:  70nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182173(4-[7-chloro-1-(2,6-difluoro-benzyl)-1H-benzoimidaz...)
Affinity DataKi:  100nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182183(4-[7-chloro-3-(2,6-difluoro-benzyl)-3H-benzoimidaz...)
Affinity DataKi:  100nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233693(CHEMBL252619 | N-[3'-(5-carbamimidoyl-2-methylsulf...)
Affinity DataKi:  120nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233680(4-(2'-hydroxymethyl-biphenyl-3-sulfonyl)-5-methyls...)
Affinity DataKi:  120nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50312659(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  120nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233681(5-methylsulfanyl-4-(2'-vinyl-biphenyl-3-sulfonyl)-...)
Affinity DataKi:  140nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233676(3'-(5-carbamimidoyl-2-methylsulfanyl-thiophene-3-s...)
Affinity DataKi:  150nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233683(4-(3'-hydroxy-biphenyl-3-sulfonyl)-5-methylsulfany...)
Affinity DataKi:  150nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182164(4-[7-bromo-3-(2,6-dichloro-benzyl)-3H-benzoimidazo...)
Affinity DataKi:  160nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182181(4-[7-bromo-3-(2,6-difluoro-benzyl)-3H-benzoimidazo...)
Affinity DataKi:  170nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182174(4-[7-bromo-3-(2-fluoro-5-nitro-benzyl)-3H-benzoimi...)
Affinity DataKi:  170nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182180(4-(7-bromo-3-phenyl-3H-benzoimidazole-5-sulfonyl)-...)
Affinity DataKi:  180nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233678(4-(4'-hydroxy-biphenyl-3-sulfonyl)-5-methylsulfany...)
Affinity DataKi:  190nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182153(4-[7-bromo-3-(3-methyl-but-2-enyl)-3H-benzoimidazo...)
Affinity DataKi:  200nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182182(4-(3-allyl-7-bromo-3H-benzoimidazole-5-sulfonyl)-5...)
Affinity DataKi:  210nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182169(4-[7-bromo-3-(2,5-difluoro-benzyl)-3H-benzoimidazo...)
Affinity DataKi:  240nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233687(4-(4'-methyl-biphenyl-3-sulfonyl)-5-methylsulfanyl...)
Affinity DataKi:  250nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50233675(4-(biphenyl-3-sulfonyl)-5-methylsulfanyl-thiophene...)
Affinity DataKi:  260nMAssay Description:Inhibition of Complement C1s subcomponentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182186(4-(7-bromo-1-phenyl-1H-benzoimidazole-5-sulfonyl)-...)
Affinity DataKi:  310nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182161(4-(7-bromo-3-methyl-3H-benzoimidazole-5-sulfonyl)-...)
Affinity DataKi:  330nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1s subcomponent(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182156(4-[7-bromo-1-((S)-1-phenyl-ethyl)-1H-benzoimidazol...)
Affinity DataKi:  330nMAssay Description:Inhibition of C1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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