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Found 164 with Last Name = 'barnes' and Initial = 'mh'
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182669((S)-3-{4-[1-(1-cyclopropyl-3-carboxy-4-oxo-6,8-dif...)
Affinity DataKi:  4nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182665((R)-3-{4-[1-(1-cyclopropyl-3-carboxy-4-oxo-6,8-dif...)
Affinity DataKi:  7nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182666(3-{4-[1-(1-cyclopropyl-3-carboxy-4-oxo-6-fluoro-8-...)
Affinity DataKi:  10nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182662((S)-3-{4-[1-(1-cyclopropyl-3-carboxy-4-oxo-6-fluor...)
Affinity DataKi:  11nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182667(3-{4-[1-(1-cyclopropyl-3-carboxy-4-oxo-6,8-difluor...)
Affinity DataKi:  11nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182674((R)-3-{4-[1-(1-cyclopropyl-3-carboxy-4-oxo-6-fluor...)
Affinity DataKi:  12nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182659(3-{4-[1-(1-tert-butyl-3-carboxy-4-oxo-6-fluoro-7-q...)
Affinity DataKi:  13nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182663(3-{4-[1-(1-cyclopropyl-3-carboxy-4-oxo-6-fluoro-8-...)
Affinity DataKi:  14nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182673(3-{4-[1-(1-(4-fluorophenyl)-3-carboxy-4-oxo-6-fluo...)
Affinity DataKi:  17nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182672(1-ethyl-7-(4-(4-(4-(3-ethyl-4-methylphenylamino)-2...)
Affinity DataKi:  18nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182676(3-{4-[1-(1-{2,4-difluorophenyl}-3-carboxy-4-oxo-6-...)
Affinity DataKi:  18nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM21688(1-cyclopropyl-7-[4-(4-{4-[(3-ethyl-4-methylphenyl)...)
Affinity DataKi:  19nM ΔG°:  -44.8kJ/molepH: 7.5 T: 2°CAssay Description:Reaction velocities were determined at each dGTP concentration and used to create double reciprocal plots of velocity versus dGTP concentration. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182671(3-{5-[1-(1-cyclopropyl-3-carboxy-4-oxo-6-fluoro-7-...)
Affinity DataKi:  19nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM21688(1-cyclopropyl-7-[4-(4-{4-[(3-ethyl-4-methylphenyl)...)
Affinity DataKi:  19nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182670(3-{4-[1-(1-ethyl-3-carboxy-4-oxo-6,8-difluoro-7-qu...)
Affinity DataKi:  21nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182675(3-{4-[1-(1-cyclopropyl-3-carboxy-4-oxo-6-fluoro-7-...)
Affinity DataKi:  24nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182668(3-{4-[1-(1-ethyl-3-carboxy-4-oxo-6-fluoro-7-quinol...)
Affinity DataKi:  24nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182656(3-{4-[1-(1-cyclopropyl-3-carboxy-4-oxo-6-fluoro-7-...)
Affinity DataKi:  26nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III subunit alpha(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160350(Acetic acid (R)-5-[2-(3,4-dichloro-benzylamino)-6-...)
Affinity DataKi:  31nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182657(3-{5-[1-(1-cyclopropyl-3-carboxy-4-oxo-6-fluoro-7-...)
Affinity DataKi:  33nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III subunit alpha(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160340(2-(3,4-Dichloro-benzylamino)-7-((R)-5-hydroxy-hexy...)
Affinity DataKi:  35nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182664(3-{5-[1-(1-ethyl-3-carboxy-4-oxo-6-fluoro-7-quinol...)
Affinity DataKi:  37nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182658(3-{5-[1-(1-cyclopropyl-3-carboxy-6-fluoro-4-oxo-7-...)
Affinity DataKi:  41nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III subunit alpha(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160338(4-[2-(3,4-Dichloro-benzylamino)-6-oxo-1,6-dihydro-...)
Affinity DataKi:  47nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III subunit alpha(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160342(2-(3,4-Dichloro-benzylamino)-7-(4-morpholin-4-yl-b...)
Affinity DataKi:  47nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160342(2-(3,4-Dichloro-benzylamino)-7-(4-morpholin-4-yl-b...)
Affinity DataKi:  51nMAssay Description:Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160340(2-(3,4-Dichloro-benzylamino)-7-((R)-5-hydroxy-hexy...)
Affinity DataKi:  52nMAssay Description:Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160344(Acetic acid 5-[2-(3,4-dichloro-benzylamino)-6-oxo-...)
Affinity DataKi:  52nMAssay Description:Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160345(2-(3,4-Dichloro-benzylamino)-7-(5-hydroxy-pentyl)-...)
Affinity DataKi:  52nMAssay Description:Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III subunit alpha(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160344(Acetic acid 5-[2-(3,4-dichloro-benzylamino)-6-oxo-...)
Affinity DataKi:  58nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III subunit alpha(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160351(2-(3,4-Dichloro-benzylamino)-7-(4-hydroxy-butyl)-1...)
Affinity DataKi:  63nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM21686(3-(4-hydroxybutyl)-6-(3-ethyl-4-methylanilino)urac...)
Affinity DataKi:  63nM ΔG°:  -41.8kJ/molepH: 7.5 T: 2°CAssay Description:Reaction velocities were determined at each dGTP concentration and used to create double reciprocal plots of velocity versus dGTP concentration. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160343(Acetic acid 4-[2-(3,4-dichloro-benzylamino)-6-oxo-...)
Affinity DataKi:  66nMAssay Description:Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM21686(3-(4-hydroxybutyl)-6-(3-ethyl-4-methylanilino)urac...)
Affinity DataKi:  66nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III subunit alpha(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160360(2-(3,4-Dichloro-benzylamino)-7-(5-methanesulfinyl-...)
Affinity DataKi:  68nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160356(2-(3,4-Dichloro-benzylamino)-7-(5-methoxy-pentyl)-...)
Affinity DataKi:  70nMAssay Description:Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III subunit alpha(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160341(2-(3,4-Dichloro-benzylamino)-7-(2-ethoxy-ethyl)-1,...)
Affinity DataKi:  72nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160350(Acetic acid (R)-5-[2-(3,4-dichloro-benzylamino)-6-...)
Affinity DataKi:  80nMAssay Description:Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III subunit alpha(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160356(2-(3,4-Dichloro-benzylamino)-7-(5-methoxy-pentyl)-...)
Affinity DataKi:  88nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III subunit alpha(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160353(2-(3,4-Dichloro-benzylamino)-7-(5-methanesulfonyl-...)
Affinity DataKi:  90nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III subunit alpha(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160345(2-(3,4-Dichloro-benzylamino)-7-(5-hydroxy-pentyl)-...)
Affinity DataKi:  91nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160360(2-(3,4-Dichloro-benzylamino)-7-(5-methanesulfinyl-...)
Affinity DataKi:  93nMAssay Description:Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50182660(3-{4-[1-(1-cyclopropyl-3-carboxy-4-oxo-6-fluoro-7-...)
Affinity DataKi:  95nMAssay Description:Binding affinity to Bacillus subtilis DNA polymerase3CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III subunit alpha(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160355(CHEMBL181398 | Isobutyric acid 5-[2-(3,4-dichloro-...)
Affinity DataKi:  110nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III subunit alpha(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160346(2-(3,4-Dichloro-benzylamino)-7-[2-(2-hydroxy-ethox...)
Affinity DataKi:  110nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III subunit alpha(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160343(Acetic acid 4-[2-(3,4-dichloro-benzylamino)-6-oxo-...)
Affinity DataKi:  120nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III subunit alpha(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160347(4-[2-(3,4-Dichloro-benzylamino)-6-oxo-1,6-dihydro-...)
Affinity DataKi:  130nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160338(4-[2-(3,4-Dichloro-benzylamino)-6-oxo-1,6-dihydro-...)
Affinity DataKi:  150nMAssay Description:Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160347(4-[2-(3,4-Dichloro-benzylamino)-6-oxo-1,6-dihydro-...)
Affinity DataKi:  170nMAssay Description:Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III subunit alpha(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160352(2-(3,4-Dichloro-benzylamino)-7-(5-methylsulfanyl-p...)
Affinity DataKi:  180nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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