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Found 196 with Last Name = 'bazin' and Initial = 'm'
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360473(CHEMBL1934749)
Affinity DataKi:  6nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360475(CHEMBL1934751)
Affinity DataKi:  11nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50074501(Butyl-ethyl-[2,5,6-trimethyl-7-(2,4,6-trimethyl-ph...)
Affinity DataKi:  32nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360474(CHEMBL1934750)
Affinity DataKi:  52nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM18627((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at progesterone receptorMore data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360470(CHEMBL1934746)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50568546(CHEMBL4853288)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374929(CHEMBL402364)
Affinity DataIC50:  60nMAssay Description:Inhibition of human integrin alpha-4-beta-7-MAdCAM interaction in human RPMI 8866 cells by whole-cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50568545(CHEMBL4877608)
Affinity DataIC50:  160nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50568544(CHEMBL4870529)
Affinity DataIC50:  160nMAssay Description:Inhibition of recombinant human CK1 epsilon expressed in baculovirus infected Sf9 cells using RRKHAAIGSpAYSITA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374925(CHEMBL272367)
Affinity DataIC50:  180nMAssay Description:Inhibition of human integrin alpha-4-beta-7-MAdCAM interaction in human RPMI 8866 cells by whole-cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50568545(CHEMBL4877608)
Affinity DataIC50:  180nMAssay Description:Inhibition of recombinant human CK1 epsilon expressed in baculovirus infected Sf9 cells using RRKHAAIGSpAYSITA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50568546(CHEMBL4853288)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant human CK1 epsilon expressed in baculovirus infected Sf9 cells using RRKHAAIGSpAYSITA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Pfizer

LigandPNGBDBM81848(Bipiperidinyl carboxylic acid amide, 20)
Affinity DataIC50:  200nMAssay Description:Cell-based assay for CCR4 was developed to screen small-molecule compound library using a Fluorometric Imaging Plate Reader (FlIPR) assay to identify...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50:  220nMAssay Description:Inhibition of recombinant human CDK9/CyclinT using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 90 mins by LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50568544(CHEMBL4870529)
Affinity DataIC50:  250nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374930(CHEMBL257458)
Affinity DataIC50:  260nMAssay Description:Inhibition of human integrin alpha-4-beta-7-MAdCAM interaction in human RPMI 8866 cells by whole-cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50:  300nMAssay Description:Inhibition of human PKCbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360471(CHEMBL1934747)
Affinity DataIC50:  307nMAssay Description:Antagonist activity at progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360469(CHEMBL1934745)
Affinity DataIC50:  430nMAssay Description:Antagonist activity at progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50568546(CHEMBL4853288)
Affinity DataIC50:  500nMAssay Description:Inhibition of human recombinant CDK9/CyclinT expressed in baculovirus infected Sf9 cells using YSPTSPSYSPTSPSYSPTSPSKKK as substrate in presence of [...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50568541(CHEMBL4860872)
Affinity DataIC50:  590nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50:  770nMAssay Description:Inhibition of recombinant human CDK2/Cyclin A using ATP and Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 30 mins by LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50360472(CHEMBL1934748)
Affinity DataIC50:  771nMAssay Description:Antagonist activity at progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50568546(CHEMBL4853288)
Affinity DataIC50:  800nMAssay Description:Inhibition of human CDK2/ cyclinA using histone H1 as substrate in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374933(CHEMBL402647)
Affinity DataIC50:  900nMAssay Description:Inhibition of human integrin alpha-4-beta-7-MAdCAM interaction in human RPMI 8866 cells by whole-cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50568540(CHEMBL4872681)
Affinity DataIC50:  900nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50568538(CHEMBL3634367)
Affinity DataIC50:  920nMAssay Description:Inhibition of recombinant human CK1 epsilon expressed in baculovirus infected Sf9 cells using RRKHAAIGSpAYSITA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374928(CHEMBL404714)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human integrin alpha-4-beta-7-MAdCAM interaction in human RPMI 8866 cells by whole-cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50568545(CHEMBL4877608)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant CDK5/ p25 expressed in bacterial expression system using histone H1 as substrate in presence of [gamma-33P]ATP by rad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50568541(CHEMBL4860872)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of recombinant human CK1 epsilon expressed in baculovirus infected Sf9 cells using RRKHAAIGSpAYSITA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Sus scrofa)
Universit£

Curated by ChEMBL
LigandPNGBDBM50568546(CHEMBL4853288)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of pig brain GSK alpha/beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrate in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50274761(CHEMBL4127885)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of recombinant human PIM1 using CREBtide as substrate after 60 mins by LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374935(CHEMBL271052)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human integrin alpha-4-beta-7-MAdCAM interaction in human RPMI 8866 cells by whole-cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374927(CHEMBL255836)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human integrin alpha-4-beta-7-MAdCAM interaction in human RPMI 8866 cells by whole-cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374926(CHEMBL272366)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human integrin alpha-4-beta-7-MAdCAM interaction in human RPMI 8866 cells by whole-cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50568545(CHEMBL4877608)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate in presence of [gamma-33P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50568536(CHEMBL4866187)
Affinity DataIC50:  2.08E+3nMAssay Description:Inhibition of recombinant human CK1 epsilon expressed in baculovirus infected Sf9 cells using RRKHAAIGSpAYSITA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374923(CHEMBL255561)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human integrin alpha-4-beta-7-MAdCAM interaction in human RPMI 8866 cells by whole-cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Pfizer

LigandPNGBDBM81834(Bipiperidinyl carboxylic acid amide, 7)
Affinity DataIC50:  2.30E+3nMAssay Description:Cell-based assay for CCR4 was developed to screen small-molecule compound library using a Fluorometric Imaging Plate Reader (FlIPR) assay to identify...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human Aurora-B using full-length histone H3 as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Pfizer

LigandPNGBDBM81830(Bipiperidinyl carboxylic acid amide, 3)
Affinity DataIC50:  2.50E+3nMAssay Description:Cell-based assay for CCR4 was developed to screen small-molecule compound library using a Fluorometric Imaging Plate Reader (FlIPR) assay to identify...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50274761(CHEMBL4127885)
Affinity DataIC50:  2.69E+3nMAssay Description:Inhibition of mouse CLK1 using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 30 mins by LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50568539(CHEMBL4875029)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of recombinant human CK1 epsilon expressed in baculovirus infected Sf9 cells using RRKHAAIGSpAYSITA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Pfizer

LigandPNGBDBM81837(Bipiperidinyl carboxylic acid amide, 1)
Affinity DataIC50:  3.00E+3nMAssay Description:Cell-based assay for CCR4 was developed to screen small-molecule compound library using a Fluorometric Imaging Plate Reader (FlIPR) assay to identify...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Pfizer

LigandPNGBDBM81836(Bipiperidinyl carboxylic acid amide, 9)
Affinity DataIC50:  3.50E+3nMAssay Description:Cell-based assay for CCR4 was developed to screen small-molecule compound library using a Fluorometric Imaging Plate Reader (FlIPR) assay to identify...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Pfizer

LigandPNGBDBM81832(Bipiperidinyl carboxylic acid amide, 6)
Affinity DataIC50:  3.70E+3nMAssay Description:Cell-based assay for CCR4 was developed to screen small-molecule compound library using a Fluorometric Imaging Plate Reader (FlIPR) assay to identify...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374934(CHEMBL271051)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human integrin alpha-4-beta-7-MAdCAM interaction in human RPMI 8866 cells by whole-cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50568546(CHEMBL4853288)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of recombinant human HASPIN (470 to 798 residues) expressed in bacterial expression system using ARTKQTARKSTGGKAPRKQLA as substrate in pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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