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Found 83 with Last Name = 'blanot' and Initial = 'd'
TargetUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase(Staphylococcus aureus)
University of Ljubljana

LigandPNGBDBM50248217(1-(4-Methoxyphenylsulfonamido)-3-morpholinopropan-...)
Affinity DataIC50:  6.00E+3nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447032(CHEMBL3116334)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447035(CHEMBL3116331)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447044(CHEMBL3112645)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447037(CHEMBL3116329)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase(Staphylococcus aureus)
University of Ljubljana

LigandPNGBDBM85276(HEA derivative, 7c | MurC/D/E/F inhibitor (compoun...)
Affinity DataIC50:  5.70E+4nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447048(CHEMBL3112637)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447036(CHEMBL3116330)
Affinity DataIC50:  6.10E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase(Staphylococcus aureus)
University of Ljubljana

LigandPNGBDBM85279(HEA derivative, 7f)
Affinity DataIC50:  6.10E+4nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447033(CHEMBL3116333)
Affinity DataIC50:  6.10E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447050(CHEMBL3112632)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50176461(2-(hydroxy-{1-[(R)-2-(4-nitro-phenylmethanesulfony...)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibitory activity against MurD from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447049(CHEMBL3112633)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM26455((2R)-2-({6-[(4-cyano-2-fluorophenyl)methoxy]naphth...)
Affinity DataIC50:  8.50E+4nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50176463(2-{[1-((E)-3-benzo[1,3]dioxol-5-yl-acryloylamino)-...)
Affinity DataIC50:  9.50E+4nMAssay Description:Inhibitory activity against MurD from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM26454((2R)-2-({6-[(4-cyano-2-methoxyphenyl)methoxy]napht...)
Affinity DataIC50:  1.00E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50176464(2-[(1-benzyloxycarbonylamino-ethyl)-hydroxy-phosph...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory activity against MurD from Streptococcus pneumoniaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447045(CHEMBL3112644)
Affinity DataIC50:  1.03E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM26453((2R)-2-({6-[(4-cyanophenyl)methoxy]naphthalene-2-}...)
Affinity DataIC50:  1.05E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447040(CHEMBL3116326)
Affinity DataIC50:  1.07E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447038(CHEMBL3116328)
Affinity DataIC50:  1.09E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447034(CHEMBL3116332)
Affinity DataIC50:  1.17E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447041(CHEMBL3112648)
Affinity DataIC50:  1.19E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase(Staphylococcus aureus)
University of Ljubljana

LigandPNGBDBM50248218(1-(4-Fluorophenylsulfonamido)-3-morpholinopropan-2...)
Affinity DataIC50:  1.20E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase(Staphylococcus aureus)
University of Ljubljana

LigandPNGBDBM85278(HEA derivative, 7e)
Affinity DataIC50:  1.20E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM26456((2R)-2-({7-[(4-cyanophenyl)methoxy]naphthalene-2-}...)
Affinity DataIC50:  1.22E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447043(CHEMBL3112646)
Affinity DataIC50:  1.25E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447055(CHEMBL3112590)
Affinity DataIC50:  1.26E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447052(CHEMBL3112630)
Affinity DataIC50:  1.28E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM26452((2R)-2-{[6-(3-phenylpropoxy)naphthalene-2-]sulfona...)
Affinity DataIC50:  1.32E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Escherichia coli)
University of Ljubljana

LigandPNGBDBM85277(HEA derivative, 7d)
Affinity DataIC50:  1.50E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447046(CHEMBL3112640)
Affinity DataIC50:  1.54E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase(Staphylococcus aureus)
University of Ljubljana

LigandPNGBDBM85277(HEA derivative, 7d)
Affinity DataIC50:  1.60E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447051(CHEMBL3112631)
Affinity DataIC50:  1.67E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447053(CHEMBL3112629)
Affinity DataIC50:  1.70E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM26445((2R)-2-{[6-(pentyloxy)naphthalene-2-]sulfonamido}p...)
Affinity DataIC50:  1.70E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447047(CHEMBL3112639)
Affinity DataIC50:  1.72E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM26446((2R)-2-{[6-(hexyloxy)naphthalene-2-]sulfonamido}pe...)
Affinity DataIC50:  1.76E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM26464((2R)-2-[(7-butoxynaphthalene-2-)sulfonamido]pentan...)
Affinity DataIC50:  1.80E+5nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM26447((2R)-2-{[6-(2-ethoxy-2-oxoethoxy)naphthalene-2-]su...)
Affinity DataIC50:  1.92E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
University of Ljubljana

LigandPNGBDBM85276(HEA derivative, 7c | MurC/D/E/F inhibitor (compoun...)
Affinity DataIC50:  2.00E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50447054(CHEMBL3112649)
Affinity DataIC50:  2.19E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM26451((2R)-2-{[6-(benzyloxy)naphthalene-2-]sulfonamido}p...)
Affinity DataIC50:  2.39E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Escherichia coli)
University of Ljubljana

LigandPNGBDBM85276(HEA derivative, 7c | MurC/D/E/F inhibitor (compoun...)
Affinity DataIC50:  2.40E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Escherichia coli)
University of Ljubljana

LigandPNGBDBM50248218(1-(4-Fluorophenylsulfonamido)-3-morpholinopropan-2...)
Affinity DataIC50:  2.70E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM26444((2R)-2-[(6-butoxynaphthalene-2-)sulfonamido]pentan...)
Affinity DataIC50:  2.80E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM26443((2R)-2-[(6-propoxynaphthalene-2-)sulfonamido]penta...)
Affinity DataIC50:  3.05E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Escherichia coli)
University of Ljubljana

LigandPNGBDBM85279(HEA derivative, 7f)
Affinity DataIC50:  3.60E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM26450((2R)-2-{[6-(cyclopentyloxy)naphthalene-2-]sulfonam...)
Affinity DataIC50:  4.00E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50176462(2-(hydroxy-{1-[(E)-(3-phenyl-acryloyl)amino]-ethyl...)
Affinity DataIC50:  4.32E+5nMAssay Description:Inhibitory activity against MurD from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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