Affinity DataKi: 0.270nM ΔG°: -50.8kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.540nM ΔG°: -49.2kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.40nM ΔG°: -47.0kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.65nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.70nM ΔG°: -46.5kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.5nM ΔG°: -45.6kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 3.98nM ΔG°: -44.6kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -44.6kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 4.62nM ΔG°: -44.2kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 4.90nM ΔG°: -44.1kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 6.07nM ΔG°: -43.6kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 6.10nM ΔG°: -43.6kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 6.11nM ΔG°: -43.6kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 7.10nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 7.96nM ΔG°: -43.0kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 9.56nM ΔG°: -42.5kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 11nM ΔG°: -42.2kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 11.6nM ΔG°: -42.1kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 13.7nM ΔG°: -41.7kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 14.9nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 17.0nM ΔG°: -41.2kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 5 [180-384](Homo sapiens (Human))
Texas Wesleyan University
Texas Wesleyan University
Affinity DataKi: 25nM ΔG°: -43.4kJ/mole IC50: 4.40E+4nMT: 2°CAssay Description:For the 96-well plate validation assay, sodium orthovanadate (Sigma Aldrich) was utilized as a positive control for inhibition [Swarup et al., Bioche...More data for this Ligand-Target Pair
Affinity DataKi: 30.0nM ΔG°: -39.9kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 34.8nM ΔG°: -39.6kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 36.6nM ΔG°: -39.5kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 128nM ΔG°: -36.6kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 225nM ΔG°: -35.3kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 336nM ΔG°: -34.3kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
Affinity DataKi: 630nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Binding affinity to wild type androgen receptor by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Binding affinity to wild type androgen receptor by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Binding affinity to wild type androgen receptor by competitive binding assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Concordia University Of Wisconsin
Concordia University Of Wisconsin
Affinity DataIC50: 1.10E+3nMpH: 7.0 T: 2°CAssay Description:Assays with and without inhibitor were performed in Corning 96-well clear bottom plates having a nonbinding surface, with a total assay volume of 200...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:This assay was done with full-length protein (containing both domains), andusing pERK as substrate.More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Concordia University Of Wisconsin
Concordia University Of Wisconsin
Affinity DataIC50: 2.10E+3nMpH: 7.0 T: 2°CAssay Description:Assays with and without inhibitor were performed in Corning 96-well clear bottom plates having a nonbinding surface, with a total assay volume of 200...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at wild type androgen receptor expressed in african green monkey CV1 cells assessed as inhibition of dihydrotestosterone-induced ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at wild type androgen receptor expressed in african green monkey CV1 cells assessed as inhibition of dihydrotestosterone-induced ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at wild type androgen receptor expressed in african green monkey CV1 cells assessed as inhibition of dihydrotestosterone-induced ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair