Compile Data Set for Download or QSAR
maximum 50k data
Found 458 with Last Name = 'boyer' and Initial = 'd'
TargetDipeptidyl peptidase 4(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338518(1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of DPP4 in rat plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338518(1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...)
Affinity DataKi:  14nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338518(1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of DPP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338518(1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338518(1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of POPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338518(1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338518(1-((3S,4S)-4-amino-1-(4-(3,3-difluoropyrrolidin-1-...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344013(CHEMBL1780094 | trans-(3R,5S)-N-((6-aminopyridin-2...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344014(CHEMBL1779987 | trans-(3R,5S)-1-((5-methyl-2-pheny...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50390333(CHEMBL2070733)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344015(CHEMBL1780096 | trans-(3S,5S)-5-ethyl-1-((5-methyl...)
Affinity DataIC50:  0.955nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226096(4-(((3R,4R)-3-amino-4-((2R)-2-cyanocyclopentanecar...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50390334(CHEMBL2070735)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226064(4-(((3R,4R)-3-amino-4-((2R)-2-cyanocyclopentanecar...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50390332(CHEMBL2070732)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338507((3R,4S)-1-(6-(6,7-dihydroisoxazolo[4,3-c]pyridin-5...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344016(2-((5-methyl-2-phenyloxazol-4-yl)methyl)-N-((6-met...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of PDE8AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344018(CHEMBL1779984 | trans-(3R,5R)-5-ethyl-1-((5-methyl...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of PDE8AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344017(1-((5-methyl-2-phenyloxazol-4-yl)methyl)-N-((6-met...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of PDE8AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50390334(CHEMBL2070735)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of PDE8AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344019(CHEMBL1780085 | trans-(3R,5R)-5-(methoxymethyl)-1-...)
Affinity DataIC50:  1.96nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50277775((3R,4R)-3-(4-(3,5-dimethylphenoxy)phenyl)-1-oxo-2-...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at human GPR40 expressed HEK293 cells assessed as effect on intracellular calcium concentration by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226086((S)-1-((3R,4R)-1-(4-cyanobenzyl)-3-aminopyrrolidin...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344020(CHEMBL1780116 | trans-(3R,5R)-5-ethyl-1-((5-methyl...)
Affinity DataIC50:  2.91nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226093((1R)-2-((3R,4R)-1-(1-(4-(1H-1,2,4-triazol-1-yl)phe...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226077((3S,4S)-4-amino-3-(pyrrolidine-1-carbonyl)-1-(quin...)
Affinity DataIC50: >3nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50277776((3R,4R)-3-(4-(3,4-dimethylphenoxy)phenyl)-1-oxo-2-...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at human GPR40 expressed HEK293 cells assessed as effect on intracellular calcium concentration by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344021(CHEMBL1779988 | trans-(3R,5R)-5-(methoxymethyl)-1-...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226065((S)-1-((3R,4R)-1-(4-(1H-1,2,4-triazol-1-yl)benzyl)...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226067((S)-1-((3R,4R)-1-(4-(1-methyl-1H-pyrazol-5-yl)benz...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226078(1-((3R,4R)-3-amino-4-((2R)-2-cyanocyclopentanecarb...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226074((1R)-2-((3R,4R)-3-amino-1-(chroman-4-yl)pyrrolidin...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226084((S)-1-((3R,4R)-1-(3-cyano-4-fluorobenzyl)-3-aminop...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50390373(CHEMBL2070914)
Affinity DataIC50:  3.63nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226076((1R)-2-((3R,4R)-1-(2-methyl-4-(1H-1,2,4-triazol-1-...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344022(CHEMBL1780100 | trans-(3S,5S)-5-(3-methyl-1,2,4-ox...)
Affinity DataIC50:  3.86nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344023(CHEMBL1780089 | trans-(3R,5R)-5-(3-methyl-1,2,4-ox...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278106((R)-(4-(1-amino-2-(2,4,5-trifluorophenyl)ethyl)pip...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50277814((3R,4R)-2-(cyclopropylmethyl)-1-oxo-3-(4-phenoxyph...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at human GPR40 expressed HEK293 cells assessed as effect on intracellular calcium concentration by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50390335(CHEMBL2070736)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344024(CHEMBL1780097 | trans-(3S,5S)-5-(methoxymethyl)-1-...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344025(CHEMBL1780105 | trans-(3R,5R)-5-(methoxymethyl)-1-...)
Affinity DataIC50:  4.36nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344026(CHEMBL1780111 | trans-(3R,5R)-N-((6-aminopyridin-2...)
Affinity DataIC50:  4.42nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226102(4-(((3R,4R)-3-amino-4-((2R)-2-cyanocyclopentanecar...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50249516(CHEMBL514011 | cis-2-(4-((3S,5S)-5-(3,3-difluoropy...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human plasma DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344016(2-((5-methyl-2-phenyloxazol-4-yl)methyl)-N-((6-met...)
Affinity DataIC50:  5nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50249548(CHEMBL475586 | cis-(3,3-difluoropyrrolidin-1-yl)((...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of human plasma DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50249515(CHEMBL474410 | cis-(3,3-difluoropyrrolidin-1-yl)((...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of human plasma DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50540172(CHEMBL4637426)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226092((1R,3S)-2-((3R,4R)-1-(4-(5-methyl-1,3,4-oxadiazol-...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 458 total ) | Next | Last >>
Jump to: