TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research
Curated by ChEMBL
Searle Discovery Research
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity of the compound for HIV-1 protease was determinedMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research
Curated by ChEMBL
Searle Discovery Research
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity of the compound for HIV-1 protease was determined in vitroMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Inhibitory constant aganist Protease-activated receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Compound was evaluated for its binding affinity against Histamine H3 receptor of guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research
Curated by ChEMBL
Searle Discovery Research
Curated by ChEMBL
Affinity DataKi: 3.20nMAssay Description:Binding affinity of the compound for HIV-1 protease was determined in vitroMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Compound was evaluated for its binding affinity against Histamine H3 receptor of guinea pig brain membraneMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research
Curated by ChEMBL
Searle Discovery Research
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:Binding affinity of the compound for HIV-1 protease was determined.More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Compound was evaluated for its binding affinity against Histamine H3 receptor of guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Compound was evaluated for its binding affinity against Histamine H3 receptor of guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Compound was evaluated for its binding affinity against Histamine H3 receptor of guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research
Curated by ChEMBL
Searle Discovery Research
Curated by ChEMBL
Affinity DataKi: 6.70nMAssay Description:Binding affinity of the compound for HIV-1 protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Compound was evaluated for its binding affinity against Histamine H3 receptor of guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Compound was evaluated for its binding affinity against Histamine H3 receptor of guinea pig brain membraneMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKi: 7.5nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Compound was evaluated for its binding affinity against Histamine H3 receptor of guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research
Curated by ChEMBL
Searle Discovery Research
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Binding affinity of the compound for HIV-1 protease was determined in vitro.More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibitory constant aganist Protease-activated receptor 1More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research
Curated by ChEMBL
Searle Discovery Research
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Binding affinity of the compound for HIV-1 protease was determined in vitroMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Compound was evaluated for its binding affinity against Histamine H3 receptor of guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Compound was evaluated for its binding affinity against Histamine H3 receptor of guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Compound was evaluated for its binding affinity against Histamine H3 receptor of guinea pig brain membraneMore data for this Ligand-Target Pair