Compile Data Set for Download or QSAR
maximum 50k data
Found 219 with Last Name = 'bunting' and Initial = 's'
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

LigandPNGBDBM14714((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Affinity DataKi:  0.350nM ΔG°:  -53.4kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Genentech

LigandPNGBDBM14714((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Affinity DataKi:  87nM ΔG°:  -39.9kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Genentech

LigandPNGBDBM14714((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Affinity DataKi:  114nM ΔG°:  -39.2kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Genentech

LigandPNGBDBM14714((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.5kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Genentech

LigandPNGBDBM14714((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Affinity DataKi: >3.40E+3nM ΔG°: >-30.9kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Genentech

LigandPNGBDBM14714((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Affinity DataKi: >3.50E+3nM ΔG°: >-30.8kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Genentech

LigandPNGBDBM14714((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Affinity DataKi:  3.60E+3nM ΔG°:  -30.8kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Genentech

LigandPNGBDBM14714((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Affinity DataKi: >3.90E+3nM ΔG°: >-30.6kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Genentech

LigandPNGBDBM14714((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Affinity DataKi:  4.00E+3nM ΔG°:  -30.5kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50003852((4-{2-[(4-Carbamimidoyl-benzoyl)-methyl-amino]-ace...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of FG binding to alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006294(6-Carboxymethyl-12-(3-guanidino-propyl)-5,8,11,14,...)
Affinity DataIC50:  0.5nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006294(6-Carboxymethyl-12-(3-guanidino-propyl)-5,8,11,14,...)
Affinity DataIC50:  0.5nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006340(11-Carboxymethyl-17-(3-guanidino-propyl)-4,10,13,1...)
Affinity DataIC50:  1nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50368321(CHEMBL1790447)
Affinity DataIC50:  1.30nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50003874(CHEMBL108111 | LAMIFIBAN | Ro-44-9883 | {1-[(S)-2-...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of FG binding to alpha IIb beta3 integrinMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006315(6-Carboxymethyl-12-(3-guanidino-propyl)-1,5,8,11,1...)
Affinity DataIC50:  1.40nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006315(6-Carboxymethyl-12-(3-guanidino-propyl)-1,5,8,11,1...)
Affinity DataIC50:  1.40nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006351(6-Carboxymethyl-12-(3-guanidino-propyl)-15-(4-hydr...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50368318(CHEMBL1790445)
Affinity DataIC50:  1.70nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50368320(CHEMBL1790443)
Affinity DataIC50:  1.80nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50368320(CHEMBL1790443)
Affinity DataIC50:  1.80nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50003867(CHEMBL65267 | Ro-44-3888 | {1-[(S)-2-(4-Carbamimid...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of FG binding to alpha IIb beta3 integrinMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006314(6-Carboxymethyl-12-(3-guanidino-propyl)-15-isoprop...)
Affinity DataIC50:  2nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006300(6-Carboxymethyl-12-(3-guanidino-propyl)-15-(4-hydr...)
Affinity DataIC50:  2.10nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006349(CHEMBL64787 | [3-Carbamoyl-12-(3-guanidino-propyl)...)
Affinity DataIC50:  2.5nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006287(6-Carboxymethyl-12-(3-guanidino-propyl)-15-methyl-...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006296(15-(4-Amino-butyl)-6-carboxymethyl-12-(3-guanidino...)
Affinity DataIC50:  2.60nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006297(15-Carbamoylmethyl-6-carboxymethyl-12-(3-guanidino...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006327(6-Carboxymethyl-12-(3-guanidino-propyl)-15-isoprop...)
Affinity DataIC50:  2.90nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006283(6-Carboxymethyl-12-(3-guanidino-propyl)-15-(1H-imi...)
Affinity DataIC50:  3nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006344(6-Carboxymethyl-12-(3-guanidino-propyl)-15-isobuty...)
Affinity DataIC50:  3nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006270(6-Carboxymethyl-15-(2,2-dimethyl-propyl)-12-(3-gua...)
Affinity DataIC50:  3.60nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006346(6-Carboxymethyl-12-(3-guanidino-propyl)-15-isobuty...)
Affinity DataIC50:  3.90nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006303(6-Carboxymethyl-12-(3-guanidino-propyl)-5,8,11,14,...)
Affinity DataIC50:  4nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006303(6-Carboxymethyl-12-(3-guanidino-propyl)-5,8,11,14,...)
Affinity DataIC50:  4nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006275(6-Carboxymethyl-12-(3-guanidino-propyl)-15-(1H-ind...)
Affinity DataIC50:  4nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006298(6-Carboxymethyl-12-(3-guanidino-propyl)-15-(2-meth...)
Affinity DataIC50:  4nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006345(6-Carboxymethyl-12-(3-guanidino-propyl)-15-hydroxy...)
Affinity DataIC50:  4nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006348(6-Carboxymethyl-12-(3-guanidino-propyl)-5,8,11,14,...)
Affinity DataIC50:  4.20nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006323(CHEMBL302646 | [3-Carbamoyl-12-(3-guanidino-propyl...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006327(6-Carboxymethyl-12-(3-guanidino-propyl)-15-isoprop...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of Fibrinogen binding to Fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006271(15-(2-Carboxy-ethyl)-6-carboxymethyl-12-(3-guanidi...)
Affinity DataIC50:  4.70nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006302(6-Carboxymethyl-12-(3-guanidino-propyl)-15-methyl-...)
Affinity DataIC50:  4.70nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006302(6-Carboxymethyl-12-(3-guanidino-propyl)-15-methyl-...)
Affinity DataIC50:  4.70nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006271(15-(2-Carboxy-ethyl)-6-carboxymethyl-12-(3-guanidi...)
Affinity DataIC50:  4.70nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006324(6-Carboxymethyl-12-(3-guanidino-propyl)-15-(4-hydr...)
Affinity DataIC50:  4.80nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006324(6-Carboxymethyl-12-(3-guanidino-propyl)-15-(4-hydr...)
Affinity DataIC50:  4.80nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006334(18-Biphenyl-4-yl-6-carboxymethyl-12-(3-guanidino-p...)
Affinity DataIC50:  5nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006334(18-Biphenyl-4-yl-6-carboxymethyl-12-(3-guanidino-p...)
Affinity DataIC50:  5nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006328(6-Carboxymethyl-12-(3-guanidino-propyl)-18-naphtha...)
Affinity DataIC50:  5.30nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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