Found 78 with Last Name = 'camacho-hernandez' and Initial = 'ga' TargetTransporter(Rattus norvegicus)
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]-nisoxetine from NET in Sprague-Dawley rat brain prefrontal cortex incubated for 180 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetTransporter(Rattus norvegicus)
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]-nisoxetine from NET in Sprague-Dawley rat brain prefrontal cortex incubated for 180 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of [3H]-citalopram from SERT in Sprague-Dawley rat brainstem incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]-WIN 3542875 from DAT in Sprague-Dawley rat brain striatum incubated for 120 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetTransporter(Rattus norvegicus)
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Displacement of [3H]-nisoxetine from NET in Sprague-Dawley rat brain prefrontal cortex incubated for 180 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetTransporter(Rattus norvegicus)
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 79nMAssay Description:Displacement of [3H]-nisoxetine from NET in Sprague-Dawley rat brain prefrontal cortex incubated for 180 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 785nMAssay Description:Displacement of [3H]-citalopram from SERT in Sprague-Dawley rat brainstem incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 795nMAssay Description:Displacement of [3H]-citalopram from SERT in Sprague-Dawley rat brainstem incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 964nMAssay Description:Displacement of [3H]-WIN 3542875 from DAT in Sprague-Dawley rat brain striatum incubated for 120 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 1.14E+3nMAssay Description:Displacement of [3H]-citalopram from SERT in Sprague-Dawley rat brainstem incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 1.54E+3nMAssay Description:Displacement of [3H]-WIN 3542875 from DAT in Sprague-Dawley rat brain striatum incubated for 120 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 4.87E+3nMAssay Description:Displacement of [3H]-WIN 3542875 from DAT in Sprague-Dawley rat brain striatum incubated for 120 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-citalopram from SERT in Sprague-Dawley rat brainstem incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetTransporter(Rattus norvegicus)
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-nisoxetine from NET in Sprague-Dawley rat brain prefrontal cortex incubated for 180 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-WIN 3542875 from DAT in Sprague-Dawley rat brain striatum incubated for 120 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetTransporter(Rattus norvegicus)
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-nisoxetine from NET in Sprague-Dawley rat brain prefrontal cortex incubated for 180 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as decrease in ACh-induced channel currents at -60 mV holding potential...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as decrease in ACh-induced channel currents at -60 mV holding potential...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as decrease in ACh-induced channel currents at -60 mV holding potential...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as decrease in ACh-induced channel currents at -60 mV holding potential...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as decrease in ACh-induced channel currents at -60 mV holding potential...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as decrease in ACh-induced channel currents at -60 mV holding potential...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as decrease in ACh-induced channel currents at -60 mV holding potential...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as decrease in ACh-induced channel currents at -60 mV holding potential...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 110nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in channel currents at -60 mV holding potential by tw...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 690nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 70nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 min...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 500nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 min...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 110nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 1.80E+3nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 69nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 530nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 2.50E+3nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 920nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 5.40E+3nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 890nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 1.60E+3nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 350nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in channel currents at -60 mV holding potential by tw...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 3.35E+3nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in channel currents at -60 mV holding potential by tw...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 690nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 3.35E+3nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in channel currents at -60 mV holding potential by tw...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 140nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 70nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 min...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 70nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 min...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 69nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 360nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of California-San Diego
Curated by ChEMBL
University of California-San Diego
Curated by ChEMBL
Affinity DataEC50: 2.50E+3nMAssay Description:Agonist activity at human alpha7 nAChR transfected in HEK cells assessed as increase in intracellular calcium release incubated for 30 mins in presen...More data for this Ligand-Target Pair
