Affinity DataKi: 0.00710nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Sosei Heptares
Curated by ChEMBL
Sosei Heptares
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Displacement of [3H]telcagepant from recombinant human CLR/RAMP1 expressed in Sf21 insect cell membranes measured after 60 mins by microbeta scintill...More data for this Ligand-Target Pair
Affinity DataKi: 0.0210nMAssay Description:Binding affinity against Dihydrofolate reductase of Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 0.0240nMAssay Description:Binding affinity for E. coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0240nMAssay Description:Binding affinity against Dihydrofolate reductase of Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 0.0250nMAssay Description:Inhibition of human recombinant Dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Sosei Heptares
Curated by ChEMBL
Sosei Heptares
Curated by ChEMBL
Affinity DataKi: 0.0251nMAssay Description:Displacement of [3H]telcagepant from recombinant human CLR/RAMP1 expressed in Sf21 insect cell membranes measured after 60 mins by microbeta scintill...More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Sosei Heptares
Curated by ChEMBL
Sosei Heptares
Curated by ChEMBL
Affinity DataKi: 0.0316nMAssay Description:Displacement of [3H]telcagepant from recombinant human CLR/RAMP1 expressed in Sf21 insect cell membranes measured after 60 mins by microbeta scintill...More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Sosei Heptares
Curated by ChEMBL
Sosei Heptares
Curated by ChEMBL
Affinity DataKi: 0.0316nMAssay Description:Displacement of [3H]telcagepant from recombinant human CLR/RAMP1 expressed in Sf21 insect cell membranes measured after 60 mins by microbeta scintill...More data for this Ligand-Target Pair
Affinity DataKi: 0.0350nMAssay Description:Binding affinity against Dihydrofolate reductase of Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 0.0350nMAssay Description:Binding affinity for E. coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0380nMAssay Description:Inhibitory activity against Trypanosoma cruzi dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Sosei Heptares
Curated by ChEMBL
Sosei Heptares
Curated by ChEMBL
Affinity DataKi: 0.0398nMAssay Description:Displacement of [3H]telcagepant from recombinant human CLR/RAMP1 expressed in Sf21 insect cell membranes measured after 60 mins by microbeta scintill...More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Binding affinity against Dihydrofolate reductase of Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Binding affinity for E. coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0530nMAssay Description:Inhibitory constant against bovine spleen Adenosine deaminaseMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Sosei Heptares
Curated by ChEMBL
Sosei Heptares
Curated by ChEMBL
Affinity DataKi: 0.0631nMAssay Description:Displacement of [3H]telcagepant from recombinant human CLR/RAMP1 expressed in Sf21 insect cell membranes measured after 60 mins by microbeta scintill...More data for this Ligand-Target Pair
Affinity DataKi: 0.0660nMAssay Description:Binding affinity against Dihydrofolate reductase of Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 0.0660nMAssay Description:Binding affinity for E. coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Sosei Heptares
Curated by ChEMBL
Sosei Heptares
Curated by ChEMBL
Affinity DataKi: 0.0794nMAssay Description:Displacement of [3H]telcagepant from recombinant human CLR/RAMP1 expressed in Sf21 insect cell membranes measured after 60 mins by microbeta scintill...More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Sosei Heptares
Curated by ChEMBL
Sosei Heptares
Curated by ChEMBL
Affinity DataKi: 0.0794nMAssay Description:Displacement of [3H]telcagepant from recombinant human CLR/RAMP1 expressed in Sf21 insect cell membranes measured after 60 mins by microbeta scintill...More data for this Ligand-Target Pair
Affinity DataKi: 0.0910nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibition of human recombinant Dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibition of human recombinant Dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Sosei Heptares
Curated by ChEMBL
Sosei Heptares
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]telcagepant from recombinant human CLR/RAMP1 expressed in Sf21 insect cell membranes measured after 60 mins by microbeta scintill...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibition of human recombinant Dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Apparent binding affinity of compound in Escherichia coli DHFRChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.107nMAssay Description:Inhibitory activity against Trypanosoma cruzi dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Inhibitory constant against bovine spleen Adenosine deaminaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.131nMAssay Description:Inhibitory activity against Trypanosoma cruzi dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
Affinity DataKi: 0.179nMAssay Description:Inhibitory activity against dihydrofolate reductase in humansMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
Affinity DataKi: 0.183nMAssay Description:Inhibitory activity against Trypanosoma cruzi dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nM ΔG°: -54.8kJ/mole EC50: 1.14nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of human recombinant Dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of human recombinant Dihydrofolate reductase enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Inhibition of Dihydrofolate reductase enzyme from Candida albicansMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nM ΔG°: -54.3kJ/mole EC50: 3.18nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Inhibitory constant against bovine spleen Adenosine deaminaseMore data for this Ligand-Target Pair