TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length RET kinase expressed in human HEK293 cells and measured by NanoBRET assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 257nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 363nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 780nMAssay Description:Inhibition of human choline kinase alpha1 using [methyl-14C]choline as substrate assessed as reduction in rate of incorporation of 14C from [methyl-1...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 920nMAssay Description:Inhibition of human choline kinase alpha1 using [methyl-14C]choline as substrate assessed as reduction in rate of incorporation of 14C from [methyl-1...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 920nMAssay Description:Inhibition of full-length RET kinase expressed in human HEK293 cells and measured by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human choline kinase alpha1 using [methyl-14C]choline as substrate assessed as reduction in rate of incorporation of 14C from [methyl-1...More data for this Ligand-Target Pair
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of human choline kinase alpha1 using [methyl-14C]choline as substrate assessed as reduction in rate of incorporation of 14C from [methyl-1...More data for this Ligand-Target Pair
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of human choline kinase alpha1 using [methyl-14C]choline as substrate assessed as reduction in rate of incorporation of 14C from [methyl-1...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of Plasmodium falciparum 3D7 choline kinase expressed in Escherichia coli BL21(DE3) assessed as reduction in phosphocholine formationMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of human choline kinase alpha1 using [methyl-14C]choline as substrate assessed as reduction in rate of incorporation of 14C from [methyl-1...More data for this Ligand-Target Pair
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of human choline kinase alpha1 using [methyl-14C]choline as substrate assessed as reduction in rate of incorporation of 14C from [methyl-1...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition of human choline kinase alpha1 using [methyl-14C]choline as substrate assessed as reduction in rate of incorporation of 14C from [methyl-1...More data for this Ligand-Target Pair
Affinity DataIC50: 3.27E+3nMAssay Description:Inhibition of human choline kinase alpha1 using [methyl-14C]choline as substrate assessed as reduction in rate of incorporation of 14C from [methyl-1...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of full-length RET kinase expressed in human HEK293 cells and measured by NanoBRET assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.74E+3nMAssay Description:Inhibition of human CKalpha1 assessed as reduction in 14C incorporation from [methyl-14C]choline to phosphatidylcholine using [methyl-14C]choline as ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.85E+3nMAssay Description:Inhibition of human choline kinase alpha1 using [methyl-14C]choline as substrate assessed as reduction in rate of incorporation of 14C from [methyl-1...More data for this Ligand-Target Pair
Affinity DataIC50: 9.51E+3nMAssay Description:Inhibition of human choline kinase alpha1 using [methyl-14C]choline as substrate assessed as reduction in rate of incorporation of 14C from [methyl-1...More data for this Ligand-Target Pair
Affinity DataIC50: 9.56E+3nMAssay Description:Inhibition of human choline kinase alpha1 using [methyl-14C]choline as substrate assessed as reduction in rate of incorporation of 14C from [methyl-1...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of human CKalpha1 assessed as reduction in 14C incorporation from [methyl-14C]choline to phosphatidylcholine using [methyl-14C]choline as ...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of human choline kinase alpha1 using [methyl-14C]choline as substrate assessed as reduction in rate of incorporation of 14C from [methyl-1...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.75E+4nMAssay Description:Inhibition of human choline kinase alpha1 using [methyl-14C]choline as substrate assessed as reduction in rate of incorporation of 14C from [methyl-1...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Gothenburg
Curated by ChEMBL
University Of Gothenburg
Curated by ChEMBL
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+5nMAssay Description:Inhibition of Plasmodium falciparum 3D7 choline kinase expressed in Escherichia coli BL21(DE3) assessed as reduction in phosphocholine formationMore data for this Ligand-Target Pair