Compile Data Set for Download or QSAR
maximum 50k data
Found 110 with Last Name = 'chang' and Initial = 'ty'
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of Aurora A kinaseMore data for this Ligand-Target Pair
TargetAurora kinase B(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of Aurora B kinaseMore data for this Ligand-Target Pair
TargetAurora kinase C(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKi:  4.60nMAssay Description:Inhibition of Aurora C kinaseMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM12985(5-Amido-pyrrolopyrazole 9d | CHEMBL402548 | N-{5-[...)
Affinity DataKi:  13nMAssay Description:Inhibition of Aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Taigen Biotechnology

LigandPNGBDBM11233(N-[(benzyloxy)carbonyl]-O-(tert-butyl)-L-threonyl-...)
Affinity DataKi:  53nM ΔG°:  -41.5kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Taigen Biotechnology

LigandPNGBDBM11232(N-[(benzyloxy)carbonyl]-O-(tert-butyl)-L-threonyl-...)
Affinity DataKi:  58nM ΔG°:  -41.3kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase C(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM12985(5-Amido-pyrrolopyrazole 9d | CHEMBL402548 | N-{5-[...)
Affinity DataKi:  61nMAssay Description:Inhibition of Aurora C kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM12985(5-Amido-pyrrolopyrazole 9d | CHEMBL402548 | N-{5-[...)
Affinity DataKi:  79nMAssay Description:Inhibition of Aurora B kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Taigen Biotechnology

LigandPNGBDBM11231(N-[(benzyloxy)carbonyl]-L-valyl-N1-((1S,2E)-4-etho...)
Affinity DataKi:  660nM ΔG°:  -35.3kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Taigen Biotechnology

LigandPNGBDBM11230(AG7088 analogue 2d | CHEMBL277716 | N-[(benzyloxy)...)
Affinity DataKi:  2.26E+3nM ΔG°:  -32.2kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Taigen Biotechnology

LigandPNGBDBM11229(AG7088 analogue 2a | CHEMBL20636 | N-[(5-methyliso...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.5 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using peptide cleavage assay. Cleavage products were resolved and analyzed with a reverse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330230(1-(4-(((1S)-2-Hydroxy-1-phenylethyl)amino)-5,6,7,8...)
Affinity DataIC50:  8nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330238((E)-4-(Diethylamino)-1-(4-(((1R)-2-hydroxy-1-pheny...)
Affinity DataIC50:  9nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50564437(CHEMBL4795285)
Affinity DataIC50:  11.3nMAssay Description:Inhibition of human recombinant HDAC6 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330241((E)-4-(Dimethylamino)-1-(4-[(1R)-1-phenylethyl]ami...)
Affinity DataIC50:  12nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330242((E)-4-(Dimethylamino)-1-(4-[(1S)-1-phenylpropyl]am...)
Affinity DataIC50:  12nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase tousled-like 2(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50599378(CHEMBL5204542)
Affinity DataIC50:  19nMAssay Description:Binding affinity to full length FLAG/HA/Strep-tagged TLK2 (388 to 772 residues) (unknown origin) transfected in HEK293T cells by Alexa Fluor 647 stai...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330234(1-(4-[(1R)-1-Phenylethyl]amino-5,6,7,8-tetrahydrop...)
Affinity DataIC50:  20nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  20nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330239((E)-1-(4-[(1R)-2-Hydroxy-1-phenylethyl]amino-5,6,7...)
Affinity DataIC50:  21nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50564442(CHEMBL4789410)
Affinity DataIC50:  23.9nMAssay Description:Inhibition of human recombinant HDAC1 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase tousled-like 2(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50599379(CHEMBL5188455)
Affinity DataIC50:  33nMAssay Description:Binding affinity to full length FLAG/HA/Strep-tagged TLK2 (388 to 772 residues) (unknown origin) transfected in HEK293T cells by Alexa Fluor 647 stai...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330235(1-(4-[(1R)-1-Phenylpropyl]amino-5,6,7,8-tetrahydro...)
Affinity DataIC50:  46nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330237((E)-4-(Dimethylamino)-1-(4-[(1S)-2-hydroxy-1-pheny...)
Affinity DataIC50:  70nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330240((E)-1-(4-[(1S)-2-Hydroxy-1-phenylethyl]amino-5,6,7...)
Affinity DataIC50:  89nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330232((2S)-2-Phenyl-2-[7-(vinylsulfonyl)-5,6,7,8-tetrahy...)
Affinity DataIC50:  91nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50564443(CHEMBL4782132)
Affinity DataIC50:  93.3nMAssay Description:Inhibition of human recombinant HDAC1 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50564441(CHEMBL4790678)
Affinity DataIC50:  108nMAssay Description:Inhibition of human recombinant HDAC1 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330243((E)-1-(4-[(1R)-1-Benzyl-2-hydroxyethyl]amino-5,6,7...)
Affinity DataIC50:  149nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50563419(CHEMBL4764787)
Affinity DataIC50:  160nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorogenic-(RHKKAc) as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase tousled-like 2(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50599380(CHEMBL5173181)
Affinity DataIC50:  163nMAssay Description:Binding affinity to full length FLAG/HA/Strep-tagged TLK2 (388 to 772 residues) (unknown origin) transfected in HEK293T cells by Alexa Fluor 647 stai...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50564438(CHEMBL4781354)
Affinity DataIC50:  165nMAssay Description:Inhibition of human recombinant HDAC1 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50564442(CHEMBL4789410)
Affinity DataIC50:  179nMAssay Description:Inhibition of human recombinant HDAC2 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50564437(CHEMBL4795285)
Affinity DataIC50:  182nMAssay Description:Inhibition of human recombinant HDAC1 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50563418(CHEMBL4796132)
Affinity DataIC50:  218nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorogenic-(RHKKAc) as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322820(CHEMBL1172781 | S-2-(5,6-Diphenylfuro[2,3-d]pyrimi...)
Affinity DataIC50:  223nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50564442(CHEMBL4789410)
Affinity DataIC50:  245nMAssay Description:Inhibition of human recombinant HDAC3 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50564440(CHEMBL4781490)
Affinity DataIC50:  271nMAssay Description:Inhibition of human recombinant HDAC1 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50564437(CHEMBL4795285)
Affinity DataIC50:  352nMAssay Description:Inhibition of human recombinant HDAC8 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50563418(CHEMBL4796132)
Affinity DataIC50:  407nMAssay Description:Inhibition of HDAC2 (unknown origin) using fluorogenic-(RHKKAc) as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50563419(CHEMBL4764787)
Affinity DataIC50:  481nMAssay Description:Inhibition of HDAC2 (unknown origin) using fluorogenic-(RHKKAc) as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)
Affinity DataIC50:  544nMAssay Description:Inhibition of human recombinant HDAC1 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)
Affinity DataIC50:  544nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorogenic-(RHKKAc) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50564441(CHEMBL4790678)
Affinity DataIC50:  563nMAssay Description:Inhibition of human recombinant HDAC3 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50564441(CHEMBL4790678)
Affinity DataIC50:  585nMAssay Description:Inhibition of human recombinant HDAC2 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)
Affinity DataIC50:  613nMAssay Description:Inhibition of HDAC2 (unknown origin) using fluorogenic-(RHKKAc) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)
Affinity DataIC50:  613nMAssay Description:Inhibition of human recombinant HDAC2 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)
Affinity DataIC50:  624nMAssay Description:Inhibition of HDAC3 (unknown origin) using fluorogenic-(RHKKAc) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)
Affinity DataIC50:  624nMAssay Description:Inhibition of human recombinant HDAC3 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50564436(CHEMBL4784684)
Affinity DataIC50:  685nMAssay Description:Inhibition of human recombinant HDAC1 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 110 total ) | Next | Last >>
Jump to: