Found 166 with Last Name = 'chatelain' and Initial = 'e' TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Mercachem
Curated by ChEMBL
Mercachem
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of full length human recombinant PDE4B1 using [3H]-cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Mercachem
Curated by ChEMBL
Mercachem
Curated by ChEMBL
Affinity DataIC50: 0.316nMAssay Description:Inhibition of full length human recombinant PDE4B1 using [3H]-cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Mercachem
Curated by ChEMBL
Mercachem
Curated by ChEMBL
Affinity DataIC50: 0.501nMAssay Description:Inhibition of full length human recombinant PDE4B2 using [3H]-cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Mercachem
Curated by ChEMBL
Mercachem
Curated by ChEMBL
Affinity DataIC50: 0.501nMAssay Description:Inhibition of full length human recombinant PDE4B1 using [3H]-cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Mercachem
Curated by ChEMBL
Mercachem
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Inhibition of full length human recombinant PDE4D3 using [3H]-cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Mercachem
Curated by ChEMBL
Mercachem
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Inhibition of full length human recombinant PDE4B1 using [3H]-cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Mercachem
Curated by ChEMBL
Mercachem
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Inhibition of full length human recombinant PDE4B1 using [3H]-cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Mercachem
Curated by ChEMBL
Mercachem
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Inhibition of full length human recombinant PDE4B1 using [3H]-cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Mercachem
Curated by ChEMBL
Mercachem
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human PDE4D3 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Mercachem
Curated by ChEMBL
Mercachem
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full length human recombinant PDE4B1 using [3H]-cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human PDE4A1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of Trypanosoma brucei TbrPDEB1More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Mercachem
Curated by ChEMBL
Mercachem
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human PDE4B1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Vu University Amsterdam
Curated by ChEMBL
Vu University Amsterdam
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human PDE4C1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of Trypanosoma brucei His-tagged catalytic domains of TbrPDEB1 expressed in Escherichia coli BL21 assessed as conversion of cAMP to AMP af...More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of Leishmania major recombinant PDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation proxim...More data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Affinity DataIC50: 316nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 316nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Mercachem
Curated by ChEMBL
Mercachem
Curated by ChEMBL
Affinity DataIC50: 501nMAssay Description:Inhibition of full length human recombinant PDE10A using [3H]-cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
Affinity DataIC50: 790nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
Affinity DataIC50: 790nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
Affinity DataIC50: 810nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
Affinity DataIC50: 830nMAssay Description:Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation p...More data for this Ligand-Target Pair
