Compile Data Set for Download or QSAR
maximum 50k data
Found 82 with Last Name = 'cherry' and Initial = 'jj'
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50232526(5-((2,4-difluorophenoxy)methyl)quinazoline-2,4-dia...)
Affinity DataIC50:  0.0200nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50232534(5-((2-fluorophenoxy)methyl)quinazoline-2,4-diamine...)
Affinity DataIC50:  0.0200nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237216(CHEMBL4080254)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50232538(5-((1-(2-fluorobenzyl)piperidin-4-yl)methoxy)quina...)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237201(CHEMBL4082618)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50232589(5-((3-chlorophenoxy)methyl)quinazoline-2,4-diamine...)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237200(CHEMBL4072132)
Affinity DataIC50:  0.0690nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM36530(D157493)
Affinity DataIC50:  0.0800nMAssay Description:Binding affinity towards 5-HT3 receptor in rat was evaluatedMore data for this Ligand-Target Pair
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237203(CHEMBL250072)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237199(CHEMBL4077061)
Affinity DataIC50:  0.110nMAssay Description:In vitro reversal of vecuronium-induced block in isolated guinea pig hemi-diaphragm.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237205(CHEMBL398675)
Affinity DataIC50:  0.190nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237209(CHEMBL4062544)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237211(CHEMBL4061457)
Affinity DataIC50:  0.270nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237210(CHEMBL399673)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM36534(D156095)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237217(CHEMBL342595)
Affinity DataIC50:  1nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 3 receptor was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237202(CHEMBL4103454)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237198(CHEMBL4068466)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237218(CHEMBL4072481)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50232566(5-(3-chlorobenzyloxy)quinazoline-2,4-diamine | CHE...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Luciola lateralis)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50352641(CHEMBL1733803)
Affinity DataIC50:  5nMAssay Description:Inhibition of fire fly luciferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237204(CHEMBL343543)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237206(CHEMBL4075292)
Affinity DataIC50:  11nMAssay Description:In vitro reversal of vecuronium-induced block in isolated guinea pig hemi-diaphragm.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237212(CHEMBL4100442)
Affinity DataIC50:  12nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237214(CHEMBL4084161)
Affinity DataIC50:  14nMAssay Description:Binding affinity towards 5-HT3 receptor in rat was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237208(CHEMBL4090641)
Affinity DataIC50:  16nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM14323(Fragment 20 | quinazoline-2,4-diamine)
Affinity DataIC50:  143nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237219(CHEMBL4093512)
Affinity DataIC50:  334nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237205(CHEMBL398675)
Affinity DataIC50:  630nMAssay Description:Inhibition of DHFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Luciola lateralis)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50352639(CHEMBL1719232)
Affinity DataIC50:  800nMAssay Description:Inhibition of fire fly luciferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237214(CHEMBL4084161)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of DHFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Luciola lateralis)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50352634(CHEMBL1699500)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of fire fly luciferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Luciola lateralis)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50352636(CHEMBL1721157)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of fire fly luciferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Luciola lateralis)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50352637(CHEMBL1704063)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of fire fly luciferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Luciola lateralis)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50352642(CHEMBL1709231)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of fire fly luciferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Luciola lateralis)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50352638(CHEMBL1726915)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of fire fly luciferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237213(CHEMBL4102384)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237215(CHEMBL4075512)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Luciola lateralis)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50352635(CHEMBL1720902)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of fire fly luciferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237206(CHEMBL4075292)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of DHFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237208(CHEMBL4090641)
Affinity DataIC50:  2.50E+4nMAssay Description:Binding affinity towards 5-HT3 receptor in rat was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237198(CHEMBL4068466)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of DHFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50232534(5-((2-fluorophenoxy)methyl)quinazoline-2,4-diamine...)
Affinity DataIC50: >3.00E+4nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50232589(5-((3-chlorophenoxy)methyl)quinazoline-2,4-diamine...)
Affinity DataIC50:  3.80E+4nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Luciola lateralis)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50352640(CHEMBL1712678)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of fire fly luciferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50232526(5-((2,4-difluorophenoxy)methyl)quinazoline-2,4-dia...)
Affinity DataIC50: >5.00E+4nMAssay Description:In vitro reversal of vecuronium-induced block in isolated guinea pig hemi-diaphragm.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237209(CHEMBL4062544)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of DHFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237199(CHEMBL4077061)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of DHFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237211(CHEMBL4061457)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of DHFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSurvival motor neuron protein(Homo sapiens)
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM48569(MLS000087323 | N-(3-chlorophenyl)-5-isopropyl-isox...)
Affinity DataEC50:  860nMAssay Description:Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 82 total ) | Next | Last >>
Jump to: