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Found 57 with Last Name = 'chi' and Initial = 'dy'
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50063266(6-Nitro-2-piperazin-1-yl-quinoline | 6-nitroquipaz...)
Affinity DataKi:  0.170nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50063266(6-Nitro-2-piperazin-1-yl-quinoline | 6-nitroquipaz...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50208769(2-[2-(hydroxymethyl)piperazin-1-yl]-6-nitroquinoli...)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50208770(2-[2-(ethoxymethyl)piperazin-1-yl]-6-nitroquinolin...)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)
Affinity DataKi:  0.530nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50208771(2-[(2-methoxymethyl)piperazin-1-yl]-6-nitroquinoli...)
Affinity DataKi:  0.680nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090213(6-Bromo-2-piperazin-1-yl-quinoline | CHEMBL39164)
Affinity DataKi:  0.910nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090216(6-Chloro-2-piperazin-1-yl-quinoline | CHEMBL290537)
Affinity DataKi:  1.70nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090215(2-[1,4]Diazepan-1-yl-6-nitro-quinoline | CHEMBL431...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50208772(6-nitro-2-(2-propoxymethylpiperazin-1-yl)quinoline...)
Affinity DataKi:  5.67nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090210(6-Iodo-2-piperazin-1-yl-quinoline | CHEMBL38466)
Affinity DataKi:  6.60nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090217(CHEMBL39265 | N,N'-Dimethyl-N-(6-nitro-quinolin-2-...)
Affinity DataKi:  8.40nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)
Affinity DataKi:  8.70nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090214(3-Bromo-6-nitro-2-piperazin-1-yl-quinoline | CHEMB...)
Affinity DataKi:  13nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50208768(2-[(2-butoxymethyl)piperazin-1-yl]-6-nitroquinolin...)
Affinity DataKi:  15.4nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090211(2-(3-Methyl-piperazin-1-yl)-6-nitro-quinoline | CH...)
Affinity DataKi:  22nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)
Affinity DataKi:  22nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50014407(2-(piperazin-1-yl)quinoline | 2-Piperazin-1-yl-qui...)
Affinity DataKi:  63nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090212(CHEMBL38754 | N*1*-(6-Nitro-quinolin-2-yl)-ethane-...)
Affinity DataKi:  164nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090218(6,8-Dinitro-2-piperazin-1-yl-quinoline | CHEMBL377...)
Affinity DataKi:  313nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50041604(3-(4-Chloro-phenyl)-8-((E)-3-iodo-allyl)-8-aza-bic...)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rat striatal synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50106890(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)
Affinity DataIC50:  25nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rat striatal synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50106882(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane-2-ca...)
Affinity DataIC50:  39nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rat striatal synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50106889(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)
Affinity DataIC50:  47nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rat striatal synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50106885(3-(4-Fluoro-benzoyloxy)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50:  149nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rat striatal synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50106883(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane-2-ca...)
Affinity DataIC50:  190nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rat striatal synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50106887(8-Methyl-3-phenyl-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataIC50:  308nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rat striatal synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50106884(3-(4-Fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)
Affinity DataIC50:  356nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rat striatal synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM22418(Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...)
Affinity DataIC50:  511nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rat striatal synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50106888(3-(4-Fluoro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)
Affinity DataIC50:  567nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rat striatal synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50106886(8-Methyl-3-phenyl-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataIC50:  876nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rat striatal synaptic membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50131068(6-Biphenyl-4-yl-4-oxo-4H-chromene-3-carbaldehyde |...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50131067(1-Oxo-1H-benzo[f]chromene-2-carbaldehyde | CHEMBL8...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50131074(4-Oxo-6-phenyl-4H-chromene-3-carbaldehyde | CHEMBL...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50131080(6-Chloro-7-methyl-4-oxo-4H-chromene-3-carbaldehyde...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50131075(6,8-Dibromo-4-oxo-4H-chromene-3-carbaldehyde | CHE...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50131077(6-Bromo-4-oxo-4H-chromene-3-carbaldehyde | CHEMBL8...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50131082(6-Isopropyl-4-oxo-4H-chromene-3-carbaldehyde | CHE...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50131076(4-Oxo-4H-benzo[h]chromene-3-carbaldehyde | CHEMBL8...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50131071(6,8-Dichloro-4-oxo-4H-chromene-3-carbaldehyde | CH...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50131069(6-Chloro-4-oxo-4H-chromene-3-carbaldehyde | CHEMBL...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50131068(6-Biphenyl-4-yl-4-oxo-4H-chromene-3-carbaldehyde |...)
Affinity DataIC50:  5.10E+4nMAssay Description:Compound was tested for selectivity against human T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50131073(6-Fluoro-4-oxo-4H-chromene-3-carbaldehyde | CHEMBL...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50131078(3-formylchromones | 4-Oxo-4H-chromene-3-carbaldehy...)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50131072(6-Nitro-4-oxo-4H-chromene-3-carbaldehyde | CHEMBL3...)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50131074(4-Oxo-6-phenyl-4H-chromene-3-carbaldehyde | CHEMBL...)
Affinity DataIC50:  2.40E+5nMAssay Description:Compound was tested for selectivity against human T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50131067(1-Oxo-1H-benzo[f]chromene-2-carbaldehyde | CHEMBL8...)
Affinity DataIC50:  7.80E+5nMAssay Description:Compound was tested for selectivity against human T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50131067(1-Oxo-1H-benzo[f]chromene-2-carbaldehyde | CHEMBL8...)
Affinity DataIC50: >1.00E+6nMAssay Description:Compound was tested for selectivity against LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50131079(4-Oxo-4H-chromene-2-carboxylic acid | CHEMBL83628 ...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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