TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School Of Medicine
Curated by ChEMBL
Sungkyunkwan University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.0700nMAssay Description:Displacement of [125I]IMSB from beta amyloid protein 40More data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School Of Medicine
Curated by ChEMBL
Sungkyunkwan University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.160nMAssay Description:Displacement of [125I]IMSB from beta amyloid protein 40More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School Of Medicine
Curated by ChEMBL
Sungkyunkwan University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.208nMAssay Description:Displacement of [125I]IMSB from beta amyloid protein 40More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 0.530nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.890nMAssay Description:Binding affinity to 5-HT2C receptorMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 0.910nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity to 5-HT2C receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity to 5-HT2C receptorMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School Of Medicine
Curated by ChEMBL
Sungkyunkwan University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to amyloid beta (1-42) aggregates in human Alzheimer's disease brain sectionsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of IKKbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School Of Medicine
Curated by ChEMBL
Sungkyunkwan University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Binding affinity to amyloid beta (1-42) aggregates in human Alzheimer's disease brain sectionsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Binding affinity to 5-HT2C receptorMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School Of Medicine
Curated by ChEMBL
Sungkyunkwan University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Binding affinity to amyloid beta (1-42) aggregates in human Alzheimer's disease brain sectionsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Binding affinity to 5-HT2C receptorMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:Antagonist activity towards rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Binding affinity to 5-HT2C receptorMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 5.20nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 5.20nMAssay Description:Binding affinity to 5-HT2C receptorMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 6.5nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 6.60nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 8.40nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 9.16nMAssay Description:Antagonist activity towards rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School Of Medicine
Curated by ChEMBL
Sungkyunkwan University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 9.37nMAssay Description:Displacement of [125I]IMSB from beta amyloid protein 40More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 9.5nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of the radioligand [3H]spiperone from the cloned human dopamine receptor D4 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University
Curated by ChEMBL
Inha University
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology
US Patent
Korea Institute of Science and Technology
US Patent
Affinity DataKi: 16nMAssay Description:Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of the radioligand [3H]spiperone from the cloned human Dopamine receptor D2 long expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School Of Medicine
Curated by ChEMBL
Sungkyunkwan University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 20.0nMAssay Description:Displacement of [125I]IMSB from beta amyloid protein 40More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institute Of Science And Technology
Curated by ChEMBL
Institute Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of the radioligand [3H]YM-09151-2 from cloned human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair