TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Displacement of [3H]-cytisine from alpha4beta2-nACHR in rat whole brainMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw
Curated by ChEMBL
Medical University Of Warsaw
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in CHO-K1 cell membranes incubated for 60 mins by microbeta scintillation counting...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]-cytisine from alpha4beta2-nACHR in rat whole brainMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 0.270nMAssay Description:Displacement of [3H]-cytisine from alpha4beta2-nACHR in rat whole brainMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.372nMAssay Description:Displacement of [3H]prazosin from human cloned alpha1D adrenoceptor expressed in CHO cell membranes after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Medical University Of Warsaw
Curated by ChEMBL
Medical University Of Warsaw
Curated by ChEMBL
Affinity DataKi: 0.398nMAssay Description:Binding affinity to 5-HT2BR (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.407nMAssay Description:Displacement of [3H]prazosin from human cloned alpha1A adrenoceptor expressed in CHO cell membranes after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 0.407nMAssay Description:Displacement of [3H]prazosin from human alpha-1A adrenoreceptor expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Displacement of [3H]prazosin from cloned human adrenergic alpha 1A receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw
Curated by ChEMBL
Medical University Of Warsaw
Curated by ChEMBL
Affinity DataKi: 0.470nMAssay Description:Displacement of [3H]-Ketanserin from human 5-HT2A receptor expressed in rat cortex tissue incubated for 30 mins by liquid scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Displacement of [3H]prazosin from human alpha-1A adrenoreceptor expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Displacement of [3H]prazosin from human cloned alpha1D adrenoceptor expressed in CHO cell membranes after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Medical University Of Warsaw
Curated by ChEMBL
Medical University Of Warsaw
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.510nMAssay Description:Displacement of [3H]prazosin from cloned human adrenergic alpha 1D receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.513nMAssay Description:Displacement of [3H]prazosin from human alpha-1D adrenoreceptor expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.513nMAssay Description:Displacement of [3H]prazosin from human cloned alpha1D adrenoceptor expressed in CHO cell membranes after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 0.646nMAssay Description:Displacement of [3H]prazosin from human cloned alpha1A adrenoceptor expressed in CHO cell membranes after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 0.708nMAssay Description:Displacement of [3H]prazosin from human cloned alpha1D adrenoceptor expressed in CHO cell membranes after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Medical University Of Warsaw
Curated by ChEMBL
Medical University Of Warsaw
Curated by ChEMBL
Affinity DataKi: 0.794nMAssay Description:Binding affinity to 5-HT2CR (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.851nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampal membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.891nMAssay Description:Displacement of [3H]prazosin from human cloned alpha1A adrenoceptor expressed in CHO cell membranes after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 0.912nMAssay Description:Displacement of [3H]prazosin from human cloned alpha1A adrenoceptor expressed in CHO cell membranes after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampal membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]prazosin from cloned human adrenergic alpha 1A receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 m...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 m...More data for this Ligand-Target Pair
Affinity DataKi: 1.41nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampal membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw
Curated by ChEMBL
Medical University Of Warsaw
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [35S] GTPgammaS from human 5-HT1A assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]prazosin from human alpha-1A adrenoreceptor expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]prazosin from cloned human adrenergic alpha 1A receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw
Curated by ChEMBL
Medical University Of Warsaw
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity to human 5-HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampal membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw
Curated by ChEMBL
Medical University Of Warsaw
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in CHO-K1 cell membranes incubated for 60 mins by microbeta scintillation counting...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]prazosin from human alpha-1D adrenoreceptor expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Medical University Of Warsaw
Curated by ChEMBL
Medical University Of Warsaw
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]-imipramine from human serotonin transporter expressed in HEK293 cells membranes incubated for 30 mins by microbeta scintillation...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 m...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Medical University Of Warsaw
Curated by ChEMBL
Medical University Of Warsaw
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Binding affinity to 5-HT2BR (unknown origin)More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 m...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of [3H]-epibatidine binding to alpha 4 beta 2 nicotinic acetylcholine receptor of rat cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]prazosin from human alpha-1A adrenoreceptor expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw
Curated by ChEMBL
Medical University Of Warsaw
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-Ketanserin from human 5-HT2A receptor expressed in rat cortex tissue incubated for 30 mins by liquid scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 2.19nMAssay Description:Displacement of [3H]prazosin from human cloned alpha1A adrenoceptor expressed in CHO cell membranes after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 2.19nMAssay Description:Displacement of [3H]prazosin from human cloned alpha1B adrenoceptor expressed in CHO cell membranes after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]prazosin from human alpha-1D adrenoreceptor expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 m...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw
Curated by ChEMBL
Medical University Of Warsaw
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in CHO-K1 cell membranes incubated for 60 mins by microbeta scintillation counting...More data for this Ligand-Target Pair