Compile Data Set for Download or QSAR
maximum 50k data
Found 119 with Last Name = 'cocconcelli' and Initial = 'g'
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319673(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataKi:  390nMAssay Description:Displacement of [3H]-epibatidine from rat alpha7 nAchR expressed in rat GH4C1 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399293(CHEMBL2086582)
Affinity DataKi:  660nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in GH4C1 cells after 1 hr by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319673(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Affinity DataKi:  6.00E+3nMAssay Description:Binding affinity to 5HT4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50259542(2-(3-Trifluoromethylphenyl)-4(5)-(3-trifluoromethy...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399295(CHEMBL2180841)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319673(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Binding affinity to human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50259388(2-(4-Chlorophenyl)-4(5)-phenylimidazole | CHEMBL50...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50259490(2-Phenyl-4(5)-(4-trifluoromethylphenyl)imidazole |...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50259541(2-(4-Nitrophenyl)-4(5)-(3-trifluoromethylphenyl)-i...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50145044(2-Phenyl-4(5)-(3-trifluoromethylphenyl)imidazole |...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399294(CHEMBL2180840)
Affinity DataIC50:  3.08E+3nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420604(CHEMBL2087443)
Affinity DataIC50:  3.25E+3nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420606(CHEMBL2087447)
Affinity DataIC50:  3.90E+3nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399289(CHEMBL2180835)
Affinity DataIC50:  4.61E+3nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319676(1-(2'-fluorobiphenyl-4-yl)-3-(4-(piperidin-1-yl)bu...)
Affinity DataIC50:  5.70E+3nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420607(CHEMBL2087448)
Affinity DataIC50:  5.80E+3nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319677(1-(4'-fluorobiphenyl-4-yl)-3-(4-(piperidin-1-yl)bu...)
Affinity DataIC50:  5.80E+3nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420605(CHEMBL2087445)
Affinity DataIC50:  6.40E+3nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319673(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Affinity DataIC50:  7.50E+3nMAssay Description:Binding affinity to adrenergic alpha2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319675(1-(2'-methoxybiphenyl-4-yl)-3-(4-(piperidin-1-yl)b...)
Affinity DataIC50:  7.80E+3nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319674(1-(biphenyl-4-yl)-3-(4-(piperidin-1-yl)butyl)urea ...)
Affinity DataIC50:  7.90E+3nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399290(CHEMBL2180836)
Affinity DataIC50:  7.94E+3nMAssay Description:Agonist activity at alpha3 nAchR in human SH-SY5Y cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420608(CHEMBL2087453)
Affinity DataIC50:  1.16E+4nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399293(CHEMBL2086582)
Affinity DataIC50:  2.42E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by IonWorks assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319673(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Agonist activity at alpha4beta2 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319678(1-(4-(6-fluoropyridin-3-yl)phenyl)-3-(4-(piperidin...)
Affinity DataIC50: >3.00E+4nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319679(1-(4-Piperidin-1-ylbutyl)-3-(4-pyridin-2-ylphenyl)...)
Affinity DataIC50: >3.00E+4nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319680(1-(6-phenylpyridin-3-yl)-3-(4-(piperidin-1-yl)buty...)
Affinity DataIC50: >3.00E+4nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319681(1-(6-(2-methoxyphenyl)pyridin-3-yl)-3-(4-(piperidi...)
Affinity DataIC50: >3.00E+4nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319682(1-(6-(2-fluorophenyl)pyridin-3-yl)-3-(4-(piperidin...)
Affinity DataIC50: >3.00E+4nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319673(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319683(1-(6'-fluoro-2,3'-bipyridin-5-yl)-3-(4-(piperidin-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319684(1-(2,2'-bipyridin-5-yl)-3-(4-(piperidin-1-yl)butyl...)
Affinity DataIC50: >3.00E+4nMAssay Description:Agonist activity at human 5HT3A receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420609(CHEMBL2087456)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420610(CHEMBL2087457)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399293(CHEMBL2086582)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420611(CHEMBL2086584)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human alpha3 receptor in SH-SY5Y cells assessed as inhibition of epibatidine-induced membrane potential measured every 1 sec f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420604(CHEMBL2087443)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420605(CHEMBL2087445)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420606(CHEMBL2087447)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420607(CHEMBL2087448)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420610(CHEMBL2087457)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399293(CHEMBL2086582)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420611(CHEMBL2086584)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420608(CHEMBL2087453)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50420609(CHEMBL2087456)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as inhibition of m-chlorophenylbiguanide-induced calcium influx measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399290(CHEMBL2180836)
Affinity DataIC50: >3.16E+4nMAssay Description:Agonist activity at human 5HT3R expressed in HEK293 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399289(CHEMBL2180835)
Affinity DataIC50: >3.16E+4nMAssay Description:Agonist activity at alpha3 nAchR in human SH-SY5Y cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 119 total ) | Next | Last >>
Jump to: