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Found 37 with Last Name = 'cosentino' and Initial = 'lm'
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50030567(6,6'-Dibromo-7,7'-dimethoxy-[4,4']bi[benzo[1,3]dio...)
Affinity DataIC50:  48nMAssay Description:IC50 value of the compound was measured as DNA dependent DNA polymerase associated activity by using 0.05 units of radiolabeled template poly(rA)-oli...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50030566(6-Bromo-7,7'-dimethoxy-[4,4']bi[benzo[1,3]dioxolyl...)
Affinity DataIC50:  56nMAssay Description:IC50 value of the compound was measured as DNA dependent DNA polymerase associated activity by using 0.05 units of radiolabeled template poly(rA)-oli...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50030567(6,6'-Dibromo-7,7'-dimethoxy-[4,4']bi[benzo[1,3]dio...)
Affinity DataIC50:  1.90E+3nMAssay Description:IC50 value of the compound was measured as RNA dependent DNA polymerase associated activity by using 10e-3 units of radiolabeled template poly(rA)-ol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50470858(CHEMBL18351)
Affinity DataIC50:  2.05E+3nMAssay Description:Inhibitory activity of the compound against tubulin polymerizationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50030566(6-Bromo-7,7'-dimethoxy-[4,4']bi[benzo[1,3]dioxolyl...)
Affinity DataIC50:  2.20E+3nMAssay Description:IC50 value of the compound was measured as RNA dependent DNA polymerase associated activity by using 1*10e-3 units of radiolabeled template poly(rC)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50030566(6-Bromo-7,7'-dimethoxy-[4,4']bi[benzo[1,3]dioxolyl...)
Affinity DataIC50:  4.50E+3nMAssay Description:IC50 value of the compound was measured as RNA dependent DNA polymerase associated activity by using 1*10e-3 units of radiolabeled template poly(rA)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50030567(6,6'-Dibromo-7,7'-dimethoxy-[4,4']bi[benzo[1,3]dio...)
Affinity DataIC50:  1.10E+4nMAssay Description:IC50 value of the compound was measured as RNA dependent DNA polymerase associated activity by using 10e-3 units of radiolabeled template poly(rC)-ol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292433(CHEMBL502585 | betulinic acid 3-O-sulfonate potass...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of PKC gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292431((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-(3-c...)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of PKC deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292432(Betulinic acid 3-O-benzoate | CHEMBL509553)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of PKC gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50103962((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bS)-1-Acet...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50002692((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292431((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-(3-c...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292433(CHEMBL502585 | betulinic acid 3-O-sulfonate potass...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292435((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-((E)...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292432(Betulinic acid 3-O-benzoate | CHEMBL509553)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50103967((3-O-acetyl)betulinic acid | 3-acetylbetulinic aci...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292434(CHEMBL509422 | betulinic acid 28-O-carboxymethylme...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23207((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-5-(hydroxymet...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM23207((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-5-(hydroxymet...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292434(CHEMBL509422 | betulinic acid 28-O-carboxymethylme...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50103967((3-O-acetyl)betulinic acid | 3-acetylbetulinic aci...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292432(Betulinic acid 3-O-benzoate | CHEMBL509553)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292435((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-((E)...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292433(CHEMBL502585 | betulinic acid 3-O-sulfonate potass...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292431((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-(3-c...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50002692((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50103962((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bS)-1-Acet...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of PKC epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50050949(3,3-Dimethyl-pentanedioic acid mono-((1S,3aS,5aR,5...)
Affinity DataIC50: >1.67E+5nMAssay Description:Inhibitory activity of the compound against HIV-RTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50050957((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-(4-c...)
Affinity DataIC50: >1.67E+5nMAssay Description:Inhibitory activity of the compound against HIV-RTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50050955(2,2-Dimethyl-succinic acid 4-((1R,3aS,5aR,5bR,7aR,...)
Affinity DataIC50: >1.71E+5nMAssay Description:Inhibitory activity of the compound against HIV-RTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50050952((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-(3-c...)
Affinity DataIC50: >1.71E+5nMAssay Description:Inhibitory activity of the compound against HIV-RTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50050951(2,2-Dimethyl-succinic acid 4-((1S,3aS,5aR,5bR,7aR,...)
Affinity DataIC50: >1.71E+5nMAssay Description:Inhibitory activity of the compound against HIV-RTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50050956((1S,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-(2-C...)
Affinity DataIC50: >1.74E+5nMAssay Description:Inhibitory activity of the compound against HIV-RTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50050954((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-(2-C...)
Affinity DataIC50: >1.75E+5nMAssay Description:Inhibitory activity of the compound against HIV-RTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50050950(Betulinic acid | CHEMBL37 | Dihydrobetulinic acid)
Affinity DataIC50: >2.18E+5nMAssay Description:Inhibitory activity of the compound against HIV-RTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM23208((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-17-hydroxy-1,...)
Affinity DataIC50: >2.19E+5nMAssay Description:Inhibitory activity of the compound against HIV-RTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed