Compile Data Set for Download or QSAR
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Found 2690 with Last Name = 'cross' and Initial = 'd'
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50131251((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
Affinity DataKi:  0.00600nMAssay Description:Binding affinity towards human Melanocortin 1 receptor (hMC1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50189013((S)-2-[(S)-4-{(R)-2-[(S)-2-acetylamino-3-(3H-imida...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to human MC1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189024((S)-2-[(S)-4-[(R)-2-[(S)-2-acetylamino-3-(4-hydrox...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataKi:  0.5nMAssay Description:Binding affinity towards human Melanocortin 1 receptor (hMC1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129420(US8802673, 62)
Affinity DataKi:  0.5nM ΔG°:  -55.2kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129366(US8802673, 8)
Affinity DataKi:  0.5nM ΔG°:  -55.2kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129410(US8802673, 52)
Affinity DataKi:  0.5nM ΔG°:  -55.2kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189010((S)-2-[(S)-4-{(R)-2-[(S)-2-acetylamino-3-(4-hydrox...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity to human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129522(US8802673, 164)
Affinity DataKi:  0.600nM ΔG°:  -54.8kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129441(US8802673, 83)
Affinity DataKi:  0.600nM ΔG°:  -54.8kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50191554((S)-2-acetamido-N-((R)-1-((2S,4R)-2-(3-guanidinopr...)
Affinity DataKi:  0.650nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataKi:  0.680nMAssay Description:Binding affinity towards human Melanocortin 3 receptor (hMC3R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129402(US8802673, 44)
Affinity DataKi:  0.700nM ΔG°:  -54.4kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189013((S)-2-[(S)-4-{(R)-2-[(S)-2-acetylamino-3-(3H-imida...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity to human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129440(US8802673, 82)
Affinity DataKi:  0.800nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129404(US8802673, 46)
Affinity DataKi:  0.800nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129457(US8802673, 99)
Affinity DataKi:  0.800nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129529(US8802673, 171)
Affinity DataKi:  0.800nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129412(US8802673, 54)
Affinity DataKi:  0.800nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129505(US8802673, 147)
Affinity DataKi:  0.900nM ΔG°:  -53.7kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50336205((N-(3-Ethoxy-phenyl)-4-pyrrolidin-1-yl-3-trifluoro...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of mouse TAAR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataKi:  0.950nMAssay Description:Binding affinity towards human melanocortin 4 receptor (hMC4R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50189010((S)-2-[(S)-4-{(R)-2-[(S)-2-acetylamino-3-(4-hydrox...)
Affinity DataKi:  1nMAssay Description:Binding affinity to human MC1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50189010((S)-2-[(S)-4-{(R)-2-[(S)-2-acetylamino-3-(4-hydrox...)
Affinity DataKi:  1nMAssay Description:Binding affinity to human MC3RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50189013((S)-2-[(S)-4-{(R)-2-[(S)-2-acetylamino-3-(3H-imida...)
Affinity DataKi:  1nMAssay Description:Binding affinity to human MC3RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129549(US8802673, 191)
Affinity DataKi:  1nM ΔG°:  -53.4kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTrace amine-associated receptor 7b(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129552(US8802673, 194)
Affinity DataKi:  1.10nM ΔG°:  -53.2kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189025((S)-2-acetamido-N1-((R)-3-(4-fluorophenyl)-1-((S)-...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50189024((S)-2-[(S)-4-[(R)-2-[(S)-2-acetylamino-3-(4-hydrox...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to human MC3RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129507(US8802673, 149)
Affinity DataKi:  1.10nM ΔG°:  -53.2kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129396(US8802673, 38)
Affinity DataKi:  1.10nM ΔG°:  -53.2kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129471(US8802673, 113)
Affinity DataKi:  1.10nM ΔG°:  -53.2kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTrace amine-associated receptor 7b(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129529(US8802673, 171)
Affinity DataKi:  1.10nM ΔG°:  -53.2kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129363(US8802673, 5)
Affinity DataKi:  1.10nM ΔG°:  -53.2kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 7b(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129569(US8802673, 211)
Affinity DataKi:  1.10nM ΔG°:  -53.2kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129411(US8802673, 53)
Affinity DataKi:  1.20nM ΔG°:  -53.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 7b(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129528(US8802673, 170)
Affinity DataKi:  1.20nM ΔG°:  -53.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129405(US8802673, 47)
Affinity DataKi:  1.20nM ΔG°:  -53.0kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189023((S)-2-((S)-4-((R)-3-(4-fluorophenyl)-2-(piperazin-...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Cincinnati

Curated by ChEMBL
LigandPNGBDBM50191569((S)-2-Acetamido-N-((R)-1-((2S,4S)-2-(3-guanidinopr...)
Affinity DataKi:  1.30nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189014((S)-2-((S)-4-((R)-2-acetamido-3-(4-fluorophenyl)pr...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 7b(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129507(US8802673, 149)
Affinity DataKi:  1.40nM ΔG°:  -52.6kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129427(US8802673, 69)
Affinity DataKi:  1.40nM ΔG°:  -52.6kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129443(US8802673, 85)
Affinity DataKi:  1.40nM ΔG°:  -52.6kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50253660(2-{3-(2-Amino-ethyl-guanidino)-4-[2-amino-3-(4-flu...)
Affinity DataKi:  1.40nMAssay Description:Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129442(US8802673, 84)
Affinity DataKi:  1.5nM ΔG°:  -52.4kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129369(US8802673, 11)
Affinity DataKi:  1.5nM ΔG°:  -52.4kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129368(US8802673, 10)
Affinity DataKi:  1.5nM ΔG°:  -52.4kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM129546(US8802673, 188)
Affinity DataKi:  1.60nM ΔG°:  -52.2kJ/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50236369((R)-1-morpholino-2-(4-(1-(thiazol-2-ylmethyl)-1H-i...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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