Affinity DataKi: 1.70E+3nMAssay Description:Tested for inhibition of Beta-secretase 1 (BACE 1) expressed in insect cell using baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nMAssay Description:Tested for inhibition of Beta-secretase 1 (BACE 1) expressed in insect cell using baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nMAssay Description:Compound was tested for inhibition of human reninMore data for this Ligand-Target Pair
Affinity DataKi: 2.20E+3nMAssay Description:Compound was tested for inhibition of cathepsin DMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMAssay Description:Tested for inhibition of Beta-secretase 1 (BACE 1) expressed in insect cell using baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 1.09E+4nMAssay Description:Compound was tested for inhibition of human reninMore data for this Ligand-Target Pair
Affinity DataKi: 1.25E+4nMAssay Description:Compound was tested for inhibition of cathepsin DMore data for this Ligand-Target Pair
Affinity DataKi: 2.44E+4nMAssay Description:Compound was tested for inhibition of human reninMore data for this Ligand-Target Pair
Affinity DataKi: 2.80E+4nMAssay Description:Compound was tested for inhibition of cathepsin DMore data for this Ligand-Target Pair
Affinity DataKi: 6.95E+4nMAssay Description:Tested for inhibition of Beta-secretase 1 (BACE 1) expressed in insect cell using baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 7.36E+4nMAssay Description:Compound was tested for inhibition of human reninMore data for this Ligand-Target Pair
Affinity DataKi: 7.97E+4nMAssay Description:Compound was tested for inhibition of cathepsin DMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of BACE1 by ECL assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.2Assay Description:Inhibition of human BACE1 expressed in mouse fibroblast cells assessed as inhibition of secreted APPbeta-NF production at pH 7.2More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of BACE1-mediated sAPP-NF processing in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.2Assay Description:Inhibition of human BACE1 expressed in mouse fibroblast cells assessed as inhibition of secreted APPbeta-NF production at pH 7.2More data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 4.5 T: 2°CAssay Description:For BACE activity assay using recombinant MBP-APP_NFEV substrate, BACE was incubated with purified MBP-APP_NFEV substrate in reaction buffer containi...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMpH: 4.5 T: 2°CAssay Description:For BACE activity assay using recombinant MBP-APP_NFEV substrate, BACE was incubated with purified MBP-APP_NFEV substrate in reaction buffer containi...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of BACE1 by ECL assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of BACE1 by ECL assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of BACE1 by ECL assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of BACE1-mediated sAPP-NF processing in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMpH: 4.5 T: 2°CAssay Description:For BACE activity assay using recombinant MBP-APP_NFEV substrate, BACE was incubated with purified MBP-APP_NFEV substrate in reaction buffer containi...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of BACE1 by ECL assayMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair