TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human 5-LOX by cell free assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of 5-LOX (unknown origin)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of 5-LOX (unknown origin)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of 5-LOX (unknown origin)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Campania "Luigi Vanvitelli
Curated by ChEMBL
University Of Campania "Luigi Vanvitelli
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
TargetMacrophage-expressed gene 1 protein(Homo sapiens (Human))
University Of Naples
Curated by ChEMBL
University Of Naples
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of mPGES1 in IL-1beta stimulated human A549 cell microsomal membranes assessed as reduction in PGE2 synthase activity after 15 mins using ...More data for this Ligand-Target Pair
TargetMacrophage-expressed gene 1 protein(Homo sapiens (Human))
University Of Naples
Curated by ChEMBL
University Of Naples
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of human mPGES1More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Second University Of Naples
Curated by ChEMBL
Second University Of Naples
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair