Affinity DataIC50: 1nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: >10nMAssay Description:Inhibition of human recombinant 11beta-HSD2More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: >10nMAssay Description:Inhibition of human recombinant 11beta-HSD2More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant DGAT1 in Chang cells using [14C]-glycerol as substrate assessed as decrease in triglycerides synthesis after 6 hrs by...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant DGAT1 expressed in baculovirus infected Sf9 cells after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant DGAT1 expressed in baculovirus infected Sf9 cells after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant DGAT1 in Chang cells using [14C]-glycerol as substrate assessed as decrease in triglycerides synthesis after 6 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant DGAT1 expressed in baculovirus infected Sf9 cells after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant DGAT1 expressed in baculovirus infected Sf9 cells after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant DGAT1 expressed in baculovirus infected Sf9 cells after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant DGAT1 in Chang cells using [14C]-glycerol as substrate assessed as decrease in triglycerides synthesis after 6 hrs by...More data for this Ligand-Target Pair