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Found 532 with Last Name = 'dayton' and Initial = 'bd'
TargetEndothelin-1 receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50051007((2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbam...)
Affinity DataIC50:  0.400nMAssay Description:Binding affinity towards endothelin A receptor in prolactin secreting rat pituitary cells using [125I]-ET-1 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056071((2R,3R,4S)-4-Benzofuran-5-yl-1-dibutylcarbamoylmet...)
Affinity DataIC50:  0.5nMAssay Description:Binding affinity towards endothelin A receptor in prolactin secreting rat pituitary cells using [125I]-ET-1 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056066((2R,3R,4S)-1-Dibutylcarbamoylmethyl-4-(2,3-dihydro...)
Affinity DataIC50:  0.600nMAssay Description:Binding affinity towards endothelin A receptor in prolactin secreting rat pituitary cells using [125I]-ET-1 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056072((2R,3R,4S)-4-Benzofuran-6-yl-1-dibutylcarbamoylmet...)
Affinity DataIC50:  0.700nMAssay Description:Binding affinity towards endothelin A receptor in prolactin secreting rat pituitary cells using [125I]-ET-1 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056057((2R,3R,4S)-1-Dibutylcarbamoylmethyl-4-(2,3-dihydro...)
Affinity DataIC50:  0.800nMAssay Description:Binding affinity towards endothelin A receptor in prolactin secreting rat pituitary cells using [125I]-ET-1 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202681(7-fluoro-4-oxo-N-(1-((2-oxo-2H-chromen-7-yl)methyl...)
Affinity DataIC50:  1nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056081((2R,3R,4S)-1-Dibutylcarbamoylmethyl-4-(2,3-dihydro...)
Affinity DataIC50:  1nMAssay Description:Binding affinity towards endothelin A receptor in prolactin secreting rat pituitary cells using [125I]-ET-1 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056075((2R,3R,4S)-1-Dibutylcarbamoylmethyl-2,4-bis-(4-met...)
Affinity DataIC50:  1.30nMAssay Description:Binding affinity towards endothelin A receptor in prolactin secreting rat pituitary cells using [125I]-ET-1 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50185040(CHEMBL204828 | N-[1-(1,3-benzodioxol-5-ylmethyl)pi...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [3H]dofetilide from hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50162116(2-(4-(benzyloxy)phenyl)-N-(1-(2-(pyrrolidin-1-yl)e...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [125I]-MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50162116(2-(4-(benzyloxy)phenyl)-N-(1-(2-(pyrrolidin-1-yl)e...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory concentration against Melanin-concentrating hormone receptor 1 in diet-induced obese miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056078((2R,3R,4S)-1-Dibutylcarbamoylmethyl-4-indan-5-yl-2...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity towards endothelin A receptor in prolactin secreting rat pituitary cells using [125I]-ET-1 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056070((2R,3R,4S)-1-Dibutylcarbamoylmethyl-4-(3,4-difluor...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity towards endothelin A receptor in prolactin secreting rat pituitary cells using [125I]-ET-1 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50167565(1-[1-(2-Isobutylamino-ethyl)-1H-indazol-5-yl]-3-(4...)
Affinity DataIC50:  1.80nMAssay Description:Inhibitory concentration against mouse Melanin-concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050056(2-[(R)-1-[(S)-2-(3-Cyclohexyl-3-methyl-ureido)-4-m...)
Affinity DataIC50:  1.80nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50171590(CHEMBL194697 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]-MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173460(4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-y...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]-MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207679(CHEMBL246258 | N-(1-(2-chloro-4-((2-(pyrrolidin-1-...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197136(CHEMBL387178 | N-[1-(1,3-benzodioxol-5-ylmethyl)pi...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056076((2R,3R,4S)-4-Benzofuran-4-yl-1-dibutylcarbamoylmet...)
Affinity DataIC50:  2nMAssay Description:Binding affinity towards endothelin A receptor in prolactin secreting rat pituitary cells using [125I]-ET-1 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197135(CHEMBL217442 | N-[1-(1,3-benzodioxol-5-ylmethyl)pi...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50171590(CHEMBL194697 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity towards melanin-concentrating hormone receptor 1 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197143(CHEMBL277531 | N-[1-(1,3-benzodioxol-5-ylmethyl)pi...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173461(4-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-ylami...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50167552(1-[1-(2-Cyclopentylamino-ethyl)-1H-indazol-5-yl]-3...)
Affinity DataIC50:  2.40nMAssay Description:Inhibitory concentration against mouse Melanin-concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197116(CHEMBL217706 | N-[1-(1,3-benzodioxol-5-ylmethyl)pi...)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [3H]dofetilide from hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201274(CHEMBL215661 | N-(1-(6-acetamido-2,3-dihydro-1H-in...)
Affinity DataIC50:  3nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173454(4-(1-Benzooxazol-5-ylmethyl-piperidin-4-ylamino)-6...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50168509(CHEMBL188937 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration required for binding affinity against mouse MCHr1 competing human neuronal IMR32 cells receptor in a radiometric binding ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197144(CHEMBL387418 | N-[1-(1,3-benzodioxol-5-ylmethyl)pi...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197139(CHEMBL214021 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50185040(CHEMBL204828 | N-[1-(1,3-benzodioxol-5-ylmethyl)pi...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]-MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207681(CHEMBL248297 | N-(1-(3-fluoro-4-(3-(piperidin-1-yl...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201274(CHEMBL215661 | N-(1-(6-acetamido-2,3-dihydro-1H-in...)
Affinity DataIC50:  3nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202682(7-fluoro-N-(1-((1-methyl-2-oxo-1,2-dihydroquinolin...)
Affinity DataIC50:  3nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197139(CHEMBL214021 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  3nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197139(CHEMBL214021 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50185040(CHEMBL204828 | N-[1-(1,3-benzodioxol-5-ylmethyl)pi...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197111(CHEMBL213715 | N-[1-(1,3-benzodioxol-5-ylmethyl)pi...)
Affinity DataIC50:  3.60nMAssay Description:Displacement of [3H]dofetilide from hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197124(CHEMBL217789 | N-[1-(1,3-benzodioxol-5-ylmethyl)pi...)
Affinity DataIC50:  3.60nMAssay Description:Displacement of [3H]dofetilide from hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056060((2R,3R,4S)-1-Dibutylcarbamoylmethyl-4-(2,4-dimetho...)
Affinity DataIC50:  3.70nMAssay Description:Binding affinity towards endothelin A receptor in prolactin secreting rat pituitary cells using [125I]-ET-1 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197113(CHEMBL214731 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  4nMAssay Description:Displacement of [3H]dofetilide from hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202677(CHEMBL216104 | N-(1-(benzo[b]thiophen-5-ylmethyl)p...)
Affinity DataIC50:  4nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197113(CHEMBL214731 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  4nMAssay Description:Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207674(CHEMBL245844 | N-(1-(4-(3-(2,4-dioxothiazolidin-3-...)
Affinity DataIC50:  4nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173465(6-Methoxy-4-[1-(3-phenyl-allyl)-piperidin-4-ylamin...)
Affinity DataIC50:  4nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50185041(CHEMBL380429 | N-(4-phenoxyphenyl)-N'-[1-(2-azepan...)
Affinity DataIC50:  4nMAssay Description:Displacement of [125I]-MCH from MCHr1 expressed in IMR32 (I3.4.2) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50171580(CHEMBL196277 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity towards melanin-concentrating hormone receptor 1 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050063(2-[(R)-1-[(S)-2-(Cyclohexyl-methyl-carbamoyloxy)-4...)
Affinity DataIC50:  4.60nMAssay Description:Inhibitory activity was evaluated against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197109(CHEMBL387417 | N-[1-(1,3-benzodioxol-5-ylmethyl)pi...)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]dofetilide from hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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