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Found 45 with Last Name = 'deforrest' and Initial = 'jm'
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50018850(1-(3-Mercapto-2-methyl-propionyl)-4-phenylsulfanyl...)
Affinity DataKi:  0.400nMAssay Description:Inhibitory constant against rabbit lung Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50367254(ENALAPRILAT)
Affinity DataKi:  1.40nMAssay Description:Inhibitory activity against rabbit lung angiotensin-1 converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50018849(4-Cyclohexyl-1-{2-[hydroxy-(4-phenyl-butyl)-phosph...)
Affinity DataKi:  1.5nMAssay Description:Inhibitory activity against rabbit lung angiotensin-1 converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataKi:  1.70nMAssay Description:Inhibitory activity against rabbit lung angiotensin-1 converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50018848(1-{2-[Hydroxy-(4-phenyl-butyl)-phosphinoyl]-acetyl...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity against rabbit lung angiotensin-1 converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281226(CHEMBL328736 | N-[(S)-1-[(2R,3S)-4-((R)-Butylsulfa...)
Affinity DataIC50:  0.350nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281231((S)-4-Methyl-2-[(S)-2-(2-methyl-propane-2-sulfonyl...)
Affinity DataIC50:  1.70nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029588((2R,3S)-3-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3...)
Affinity DataIC50:  5nMAssay Description:Evaluation of inhibitory activity of the compound against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029584(CHEMBL334907 | [(1S,2S)-3-Cyclohexyl-1-hydroxy-2-(...)
Affinity DataIC50:  8.5nMAssay Description:Evaluation of inhibitory activity of the compound against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029580(CHEMBL344155 | {(1S,2S)-2-[(S)-2-((S)-2-tert-Butox...)
Affinity DataIC50:  10nMAssay Description:Evaluation of inhibitory activity of the compound against human renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281229(1H-Indole-2-carboxylic acid [(S)-1-[4-((S,S,R)-but...)
Affinity DataIC50:  11nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029589(3-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-...)
Affinity DataIC50:  15nMAssay Description:Evaluation of inhibitory activity of the compound against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029591(((1S,2S)-3-Cyclohexyl-2-{(S)-2-[(S)-2-(cyclopentan...)
Affinity DataIC50:  16nMAssay Description:Evaluation of inhibitory activity of the compound against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029586(CHEMBL407513 | {(1S,2S)-2-[(S)-2-((S)-2-tert-Butox...)
Affinity DataIC50:  29nMAssay Description:Evaluation of inhibitory activity of the compound against human renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029592(((1S,2S)-2-{(S)-2-[(S)-2-(6-Amino-hexanoylamino)-3...)
Affinity DataIC50:  31nMAssay Description:Evaluation of inhibitory activity of the compound against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029578(((1S,2S)-3-Cyclohexyl-2-{(S)-2-[(S)-2-(cyclopentan...)
Affinity DataIC50:  38nMAssay Description:Evaluation of inhibitory activity of the compound against human renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029582(CHEMBL336245 | [(1S,2S)-3-Cyclohexyl-1-hydroxy-2-(...)
Affinity DataIC50:  41nMAssay Description:Evaluation of inhibitory activity of the compound against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029581(((S)-3-Cyclohexyl-2-{(S)-2-[(S)-2-(cyclopentanecar...)
Affinity DataIC50:  44nMAssay Description:Evaluation of inhibitory activity of the compound against human renin. value in parentheses indicate no. of determinationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029581(((S)-3-Cyclohexyl-2-{(S)-2-[(S)-2-(cyclopentanecar...)
Affinity DataIC50:  44nMAssay Description:Evaluation of inhibitory activity of the compound against human renin. value in parentheses indicate no. of determinationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281234((S)-N-[(S)-4-((R,R)-Butylsulfamoyl)-1-cyclohexylme...)
Affinity DataIC50:  64nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029579(CHEMBL436018 | {(1S,2S)-3-Cyclohexyl-2-[(S)-2-[(S)...)
Affinity DataIC50:  220nMAssay Description:Evaluation of inhibitory activity of the compound against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281242((S)-N-[(S)-4-((R,R)-Butylsulfamoyl)-1-cyclohexylme...)
Affinity DataIC50:  240nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029590(CHEMBL140422 | Cyclopentanecarboxylic acid ((S)-1-...)
Affinity DataIC50:  400nMAssay Description:Evaluation of inhibitory activity of the compound against human renin. value in parentheses indicate no. of determinationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281233((S)-4-Methyl-2-(3-phenyl-propionylamino)-pentanoic...)
Affinity DataIC50:  3.50E+3nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029583(CHEMBL343814 | Cyclopentanecarboxylic acid ((S)-1-...)
Affinity DataIC50:  5.20E+3nMAssay Description:Evaluation of inhibitory activity of the compound against human renin. value in parentheses indicate no. of determinationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281238((2S,3R,4S)-4-Amino-5-cyclohexyl-2,3-dihydroxy-pent...)
Affinity DataIC50:  1.40E+4nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281223((2S,3R,4S)-5-Cyclohexyl-2,3-dihydroxy-4-(4-methyl-...)
Affinity DataIC50:  1.40E+4nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281222((S)-N-[(S)-4-((S,R)-Butylsulfamoyl)-1-cyclohexylme...)
Affinity DataIC50:  2.10E+4nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029587(((1S,2S)-3-Cyclohexyl-2-{(S)-2-[(S)-2-(cyclopentan...)
Affinity DataIC50:  2.70E+4nMAssay Description:Evaluation of inhibitory activity of the compound against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50029585(CHEMBL140146 | {(1R,2S)-2-[(S)-2-((S)-2-tert-Butox...)
Affinity DataIC50:  4.10E+4nMAssay Description:Evaluation of inhibitory activity of the compound against human renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281237(CHEMBL93724 | [(S)-1-((1S,2R,3S)-4-Butylsulfamoyl-...)
Affinity DataIC50:  5.20E+4nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281240((S)-N-[(S)-4-((S,R)-Butylsulfamoyl)-1-cyclohexylme...)
Affinity DataIC50:  1.40E+5nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281239((2R,3R,4S)-5-Cyclohexyl-2,3-dihydroxy-4-[3-(3H-imi...)
Affinity DataIC50:  3.10E+5nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281232((2R,3R,4S)-4-Amino-5-cyclohexyl-2,3-dihydroxy-pent...)
Affinity DataIC50:  4.70E+5nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281227((2R,3R,4S)-5-Cyclohexyl-2,3-dihydroxy-4-(4-methyl-...)
Affinity DataIC50:  6.80E+5nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281241(CHEMBL93587 | N-((1S,2R,3S)-4-Butylsulfamoyl-1-cyc...)
Affinity DataIC50: >1.00E+6nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281243((S)-2-Hydroxy-4-methyl-pentanoic acid ((1S,2R,3R)-...)
Affinity DataIC50: >1.00E+6nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281236((S)-2-Hydroxy-4-methyl-pentanoic acid ((1S,2R,3S)-...)
Affinity DataIC50: >1.00E+6nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281235(CHEMBL90415 | N-((1S,2R,3S)-4-Butylsulfamoyl-1-cyc...)
Affinity DataIC50: >1.00E+6nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281221(CHEMBL94013 | N-((1S,2R,3R)-4-Butylsulfamoyl-1-cyc...)
Affinity DataIC50: >1.00E+6nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281244((S)-2-Amino-N-[4-((S,R,R)-butylsulfamoyl)-1-cycloh...)
Affinity DataIC50: >1.00E+6nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281224(4-Methyl-pentanoic acid ((1S,2R,3R)-4-butylsulfamo...)
Affinity DataIC50: >1.00E+6nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281230(CHEMBL327891 | N-((1S,2R,3R)-4-Butylsulfamoyl-1-cy...)
Affinity DataIC50: >1.00E+6nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281228(4-Methyl-pentanoic acid ((1S,2R,3S)-4-butylsulfamo...)
Affinity DataIC50: >1.00E+6nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281225((S)-2-Amino-4-methyl-pentanoic acid [(2R,3S)-4-((R...)
Affinity DataIC50: >1.00E+6nMpH: 7.0Assay Description:The compound was tested for its inhibitory activity against human renal renin at pH 7More data for this Ligand-Target Pair
In DepthDetails Article