Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Ut Southwestern Medical Center
Curated by ChEMBL
Ut Southwestern Medical Center
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Binding affinity to 15-PGDH (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:Binding affinity to full length human His-MBP-TNNI3K assessed as off-rate constant in presence of rhodamine green labeled GW805818X by fluorescence c...More data for this Ligand-Target Pair
Affinity DataKi: 0.840nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma cruzi)
University Of Alabama
Curated by ChEMBL
University Of Alabama
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of Trypanosoma cruzi DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma cruzi)
University Of Alabama
Curated by ChEMBL
University Of Alabama
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition of Trypanosoma cruzi DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma cruzi)
University Of Alabama
Curated by ChEMBL
University Of Alabama
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition of Trypanosoma cruzi DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma cruzi)
University Of Alabama
Curated by ChEMBL
University Of Alabama
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Inhibition of Trypanosoma cruzi DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma cruzi)
University Of Alabama
Curated by ChEMBL
University Of Alabama
Curated by ChEMBL
Affinity DataKi: 3.60nMAssay Description:Inhibition of Trypanosoma cruzi DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma cruzi)
University Of Alabama
Curated by ChEMBL
University Of Alabama
Curated by ChEMBL
Affinity DataKi: 4.75nMAssay Description:Inhibition of Trypanosoma cruzi DHFR by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma cruzi)
University Of Alabama
Curated by ChEMBL
University Of Alabama
Curated by ChEMBL
Affinity DataKi: 5.68nMAssay Description:Inhibition of Trypanosoma cruzi DHFR by Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma cruzi)
University Of Alabama
Curated by ChEMBL
University Of Alabama
Curated by ChEMBL
Affinity DataKi: 6.60nMAssay Description:Inhibition of Trypanosoma cruzi DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.60nMAssay Description:Inhibition of human DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 11.8nMAssay Description:Inhibition of human DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity to full length mouse His-MBP-TNNI3K assessed as off-rate constant in presence of rhodamine green labeled GW805818X by fluorescence c...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of human DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
Affinity DataKi: 24.5nMAssay Description:Inhibition of human DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma cruzi)
University Of Alabama
Curated by ChEMBL
University Of Alabama
Curated by ChEMBL
Affinity DataKi: 24.9nMAssay Description:Inhibition of Trypanosoma cruzi DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [125I-BDZ-2] from wild-type human CCK2R at allosteric site expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [125I-CCK] from wild-type human CCK1R at allosteric site expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Displacement of [125I-CCK] from wild-type human CCK1R at allosteric site expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
Affinity DataKi: 49.8nMAssay Description:Inhibition of human DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 68nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
Affinity DataKi: 69nMAssay Description:Displacement of [125I-BDZ-2] from wild-type human CCK2R at allosteric site expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 71nMAssay Description:Displacement of [125I-CCK] from wild-type human CCK2R at allosteric site expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 106nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
Affinity DataKi: 127nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
Affinity DataKi: 155nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
Affinity DataKi: 166nMAssay Description:Displacement of [125I-BDZ-1] from wild-type human CCK1R at allosteric site expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Displacement of [125I-BDZ-2] from wild-type human CCK2R expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 185nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
Affinity DataKi: 187nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair