Affinity DataIC50: 30nMAssay Description:In vitro inhibition of [3H]norepinephrine uptake in rat brain synaptosomesMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of TMEM16A (unknown origin) expressed in Xenopus laevis oocytes at -60 mV holding potential by voltage-clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Binding affinity to B-RAF kinase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Competitive inhibition of recombinant B-Raf (unknown origin) expressed in HEK293 cells by FRET analysis in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A...More data for this Ligand-Target Pair
Affinity DataIC50: 136nMAssay Description:Competitive binding affinity to B-RAF kinase (unknown origin) after 60 to 120 mins by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of [3H]spiperone binding to Dopamine receptor D2 from rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of human TMEM16B expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:In vitro inhibition of [3H]5-HT transporter uptake in rat brain synaptosomesMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:In vitro inhibition of [3H]dopamine uptake in rat brain synaptosomesMore data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A...More data for this Ligand-Target Pair
Affinity DataIC50: 660nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A...More data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of rat UT-B incubated for 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 840nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
Affinity DataIC50: 925nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair