Compile Data Set for Download or QSAR
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Found 111 with Last Name = 'donkor' and Initial = 'io'
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50137938(CHEMBL177469 | {(S)-1-[2-(N'-Benzyl-hydrazinocarbo...)
Affinity DataKi:  4.70nMAssay Description:Binding affinity of the compound against porcine erythrocyte calpain I was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM23865(3-[(2S)-2-[1-(9H-fluoren-9-yl)acetamido]-4-methylp...)
Affinity DataKi:  8nM ΔG°:  -45.7kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50543556(CHEMBL4647187)
Affinity DataKi:  9nMAssay Description:Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM23866(MDL28170 | Z-Val-Phe-CHO | benzyl N-[(1S)-2-methyl...)
Affinity DataKi:  10nM ΔG°:  -45.2kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50014577(CHEMBL286722 | MDL-2170 | Z-Val-Phe-H | [(S)-1-((S...)
Affinity DataKi:  10nMAssay Description:Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50543555(CHEMBL4642092)
Affinity DataKi:  14nMAssay Description:Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50543554(CHEMBL4646991)
Affinity DataKi:  16nMAssay Description:Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50543552(CHEMBL4642290)
Affinity DataKi:  18nMAssay Description:Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50180411(CHEMBL206243 | benzyl 2-(((S)-1-oxo-3-phenylpropan...)
Affinity DataKi:  20nMAssay Description:Inhibition of cathepsin B from human brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50193489((R)-1-(4-nitrophenylsulfonyl)-N-((R,S)-1-oxo-3-phe...)
Affinity DataKi:  20nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50124028((S)-4-Methyl-2-(toluene-4-sulfonylamino)-pentanoic...)
Affinity DataKi:  20nMAssay Description:Compound tested for inhibition of porcine calpain IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50193501((R)-1-(4-iodophenylsulfonyl)-N-((R,S)-1-oxo-3-phen...)
Affinity DataKi:  33nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50193494((R)-1-(4-methoxyphenylsulfonyl)-N-((R,S)-1-oxo-3-p...)
Affinity DataKi:  37nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM23859(3-[(2S)-2-[1-(adamantan-1-yl)acetamido]-4-methylpe...)
Affinity DataKi:  41nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50193509((S)-3-(4-iodophenylsulfonyl)-N-((R,S)-1-oxo-3-phen...)
Affinity DataKi:  42nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50101321(CHEMBL299750 | [(S)-1-((S)-1-Benzyl-2-benzyloxycar...)
Affinity DataKi:  45nMAssay Description:Binding affinity of the compound was evaluated against porcine erythrocyte Calpain 1 at the S1 subsite of the enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM23857(3-[(2S)-2-(3-cyclohexylpropanamido)-4-methylpentan...)
Affinity DataKi:  50nM ΔG°:  -41.3kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50137939(CHEMBL366793 | {(S)-3-Methyl-1-[2-oxo-2-phenethylc...)
Affinity DataKi:  54nMAssay Description:Binding affinity of the compound against porcine erythrocyte calpain I was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50101317(CHEMBL301598 | [(S)-1-((S)-1-Benzyl-2-ethoxycarbam...)
Affinity DataKi:  62nMAssay Description:Binding affinity of the compound was evaluated against porcine erythrocyte Calpain 1 at the S1 subsite of the enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM23863(3-[(2S)-2-(3,3-diphenylpropanamido)-4-methylpentan...)
Affinity DataKi:  63nM ΔG°:  -40.7kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50124032(3-(Toluene-4-sulfonyl)-thiazolidine-2-carboxylic a...)
Affinity DataKi:  70nMAssay Description:Compound tested for inhibition of porcine Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50124028((S)-4-Methyl-2-(toluene-4-sulfonylamino)-pentanoic...)
Affinity DataKi:  70nMAssay Description:Compound tested for inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50193503((4S)-N-(1-oxo-3-phenylpropan-2-yl)-3-tosylthiazoli...)
Affinity DataKi:  70nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50093805(CHEMBL416281 | [(S)-1-((S)-1-Benzyl-2-oxo-2-phenet...)
Affinity DataKi:  70nMAssay Description:The compound was evaluated for inhibition of Calpain 1 from porcine erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50093805(CHEMBL416281 | [(S)-1-((S)-1-Benzyl-2-oxo-2-phenet...)
Affinity DataKi:  72nMAssay Description:Binding affinity of the compound was evaluated against porcine erythrocyte Calpain 1 at the S1 subsite of the enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50193502((S)-3-(4-bromophenylsulfonyl)-N-((R,S)-1-oxo-3-phe...)
Affinity DataKi:  74nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50137932(CHEMBL177592 | {(S)-1-[2-((R)-1-Hydrazinomethyl-2-...)
Affinity DataKi:  74nMAssay Description:Binding affinity of the compound against porcine erythrocyte calpain I was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50124029(1-(Toluene-4-sulfonyl)-pyrrolidine-2-carboxylic ac...)
Affinity DataKi:  80nMAssay Description:Compound tested for inhibition of porcine Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50244952((S)-2-ethyl-N-(1-oxo-3-phenylpropan-2-yl)-2-(3-phe...)
Affinity DataKi:  80nMAssay Description:Inhibition of pig erythrocyte mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50193507((2R)-N-(1-oxo-3-phenylpropan-2-yl)-1-tosylpyrrolid...)
Affinity DataKi:  81nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50193490((S)-3-(4-chlorophenylsulfonyl)-N-((R,S)-1-oxo-3-ph...)
Affinity DataKi:  90nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50193502((S)-3-(4-bromophenylsulfonyl)-N-((R,S)-1-oxo-3-phe...)
Affinity DataKi:  90nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50101322(CHEMBL432121 | [(S)-1-((S)-1-Benzyl-2-oxo-2-propyl...)
Affinity DataKi:  107nMAssay Description:Binding affinity of the compound was evaluated against porcine erythrocyte Calpain 1 at the S1 subsite of the enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM23861(3-[(2S)-2-(1,1-diphenylacetamido)-4-methylpentanam...)
Affinity DataKi:  108nM ΔG°:  -39.4kJ/molepH: 7.4 T: 2°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50193509((S)-3-(4-iodophenylsulfonyl)-N-((R,S)-1-oxo-3-phen...)
Affinity DataKi:  110nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50193495((S)-3-(4-fluorophenylsulfonyl)-N-((R,S)-1-oxo-3-ph...)
Affinity DataKi:  110nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50193503((4S)-N-(1-oxo-3-phenylpropan-2-yl)-3-tosylthiazoli...)
Affinity DataKi:  119nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50180418(CHEMBL378702 | benzyl 2-(((S)-1-oxo-3-phenylpropan...)
Affinity DataKi:  120nMAssay Description:Inhibition of cathepsin B from human brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50193504((R)-1-(4-bromophenylsulfonyl)-N-((R,S)-1-oxo-3-phe...)
Affinity DataKi:  128nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50193497((R)-1-(4-chlorophenylsulfonyl)-N-((R,S)-1-oxo-3-ph...)
Affinity DataKi:  141nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50069792((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...)
Affinity DataKi:  150nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50069792((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...)
Affinity DataKi:  190nMAssay Description:Inhibition of pig erythrocyte mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50193506((R)-1-(naphthalen-1-ylsulfonyl)-N-((R,S)-1-oxo-3-p...)
Affinity DataKi:  191nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50193493((R)-N-((R,S)-1-oxo-3-phenylpropan-2-yl)-1-(phenyls...)
Affinity DataKi:  196nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50101318(CHEMBL50655 | [(S)-1-((S)-1-Benzyl-2-ethylcarbamoy...)
Affinity DataKi:  200nMAssay Description:Binding affinity of the compound was evaluated against porcine erythrocyte Calpain 1 at the S1 subsite of the enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50193490((S)-3-(4-chlorophenylsulfonyl)-N-((R,S)-1-oxo-3-ph...)
Affinity DataKi:  230nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain small subunit 1(Sus scrofa)
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50124030(1-(Toluene-4-sulfonyl)-azetidine-2-carboxylic acid...)
Affinity DataKi:  250nMAssay Description:Compound tested for inhibition of porcine Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50193505((R)-1-(3-nitrophenylsulfonyl)-N-((R,S)-1-oxo-3-phe...)
Affinity DataKi:  256nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50543553(CHEMBL4640485)
Affinity DataKi:  273nMAssay Description:Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
University of Tennessee Health Science Center

LigandPNGBDBM50193500((R)-N-(2(R,S)-3,4-dioxo-4-(phenethylamino)-1-pheny...)
Affinity DataKi:  280nMAssay Description:Inhibition of porcine erythrocyte mu calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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