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Found 289 with Last Name = 'doppalapudi' and Initial = 'vr'
TargetPlacenta growth factor(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339214(CHEMBL1689480)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of mouse PlGF-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339212(CHEMBL1689483)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human PlGF-1-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339209(CHEMBL1689479)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of mouse PlGF-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50079694(CHEMBL294608 | Sodium; (2S,3R)-3-methyl-4,4,7-trio...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against serine Beta-lactamase derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197001(CHEMBL238539 | N-[2'-(isoxazol-5-ylsulfamoyl)-4-ox...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339210(CHEMBL1689481)
Affinity DataIC50:  1nMAssay Description:Inhibition of human PlGF-1-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197003(CHEMBL241460 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-(2...)
Affinity DataIC50:  1.60nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339191(CHEMBL1689460)
Affinity DataIC50:  2nMAssay Description:Inhibition of human PlGF-1-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50114512(CHEMBL45136 | Sodium; (R)-3-bromo-5,5,8-trioxo-7-[...)
Affinity DataIC50:  2.90nMAssay Description:Inhibitory activity against Class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50114505(CHEMBL295625 | Sodium; (R)-3-chloro-5,5,8-trioxo-7...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against Class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339211(CHEMBL1689482)
Affinity DataIC50:  3nMAssay Description:Inhibition of human PlGF-1-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339193(CHEMBL1689463)
Affinity DataIC50:  4nMAssay Description:Inhibition of mouse PlGF-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339201(CHEMBL1689470)
Affinity DataIC50:  4nMAssay Description:Inhibition of mouse PlGF-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50079695(CHEMBL294203 | sodium (2S,3R,5R,6Z)-3-[(acetyloxy)...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against serine Beta-lactamase TEM derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339193(CHEMBL1689463)
Affinity DataIC50:  4nMAssay Description:Inhibition of human PlGF-1-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197002(CHEMBL268201 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50114504(CHEMBL45084 | Sodium; (R)-3-iodo-5,5,8-trioxo-7-[1...)
Affinity DataIC50:  4.70nMAssay Description:Inhibitory activity against Class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50114514(CHEMBL44932 | Sodium; (R)-3-[(E)-2-(2-guanidino-et...)
Affinity DataIC50:  5.5nMAssay Description:Inhibitory activity against Class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088835(CHEMBL433726 | Sodium; (R)-5,5,8-trioxo-3-[(E)-2-(...)
Affinity DataIC50:  6nMAssay Description:Inhibition of class A TEM-1 beta-lactamase derived from Enterobacter cloacaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50114518(CHEMBL297805 | Sodium; (R)-3-methanesulfonyl-5,5,8...)
Affinity DataIC50:  7.60nMAssay Description:Inhibitory activity against class A TEM-1 beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197000(CHEMBL429019 | N-(35-{[4-(3,5-dioxohexyl)phenyl]ca...)
Affinity DataIC50:  7.70nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197004(3-{2-[2-(2-{2-[2-(2-{2-[4-(3,5-dioxo-hexyl)-phenyl...)
Affinity DataIC50:  8nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50114514(CHEMBL44932 | Sodium; (R)-3-[(E)-2-(2-guanidino-et...)
Affinity DataIC50:  8.30nMAssay Description:Inhibitory activity against class A TEM-1 beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50114516(CHEMBL295322 | Sodium; (R)-3-benzenesulfonyl-5,5,8...)
Affinity DataIC50:  9.40nMAssay Description:Inhibitory activity against class A TEM-1 beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088831(CHEMBL353613 | Sodium; 3-((E)-2-carbamoyl-vinyl)-5...)
Affinity DataIC50:  10nMAssay Description:Inhibition of GC1 extended spectrum class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088827(CHEMBL355558 | Sodium; 3-((E)-2-cyano-vinyl)-5,5,8...)
Affinity DataIC50:  10nMAssay Description:The compound was evaluated for inhibition against Class C beta-lactamase derived from Enterobacter cloacae P99More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50114503(CHEMBL46478 | Sodium; (R)-3-fluoro-5,5,8-trioxo-7-...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against Class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50114521(CHEMBL42528 | Sodium; (R)-5,5,8-trioxo-3-phenylsul...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against class A TEM-1 beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088827(CHEMBL355558 | Sodium; 3-((E)-2-cyano-vinyl)-5,5,8...)
Affinity DataIC50:  12nMAssay Description:The compound was evaluated for inhibition against the GC1 extended spectrum Class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088827(CHEMBL355558 | Sodium; 3-((E)-2-cyano-vinyl)-5,5,8...)
Affinity DataIC50:  14nMAssay Description:Inhibition of class A TEM-1 beta-lactamase derived from Enterobacter cloacaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50079686(CHEMBL292093 | disodium (2S,3R,5R,6Z)-3-methyl-6-(...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against serine beta-lactamase, PC1 (class A) derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088825(CHEMBL353422 | Sodium; 3-((E)-2-nitro-vinyl)-5,5,8...)
Affinity DataIC50:  20nMAssay Description:The compound was evaluated for inhibition against the GC1 extended spectrum Class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088834(CHEMBL169392 | Sodium; 3-((E)-2-methoxycarbonyl-vi...)
Affinity DataIC50:  20nMAssay Description:Inhibition of class A TEM-1 beta-lactamase derived from Enterobacter cloacaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50196999(CHEMBL413001 | N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2...)
Affinity DataIC50:  21.6nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50114501(CHEMBL289979 | Sodium; (R)-3-((E)-2-carbamoyl-viny...)
Affinity DataIC50:  22nMAssay Description:Inhibitory activity against Class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50114521(CHEMBL42528 | Sodium; (R)-5,5,8-trioxo-3-phenylsul...)
Affinity DataIC50:  22nMAssay Description:Inhibitory activity against Class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50079689(CHEMBL303053 | Sodium; (2S,3R)-3-[2-(3,4-dihydroxy...)
Affinity DataIC50:  26nMAssay Description:Inhibitory activity against serine Beta-lactamase derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088831(CHEMBL353613 | Sodium; 3-((E)-2-carbamoyl-vinyl)-5...)
Affinity DataIC50:  26nMAssay Description:Affinity for alpha4-beta1 integrin from HL60 cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088817(CHEMBL355288 | Sodium; 3-cyano-5,5,8-trioxo-7-[1-p...)
Affinity DataIC50:  29nMAssay Description:Inhibition of class C beta-lactamase derived from Enterobacter cloacae P99More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50033680(CHEMBL268919 | Sodium; (R)-3-acetoxymethyl-7-[1-te...)
Affinity DataIC50:  30nMAssay Description:The compound was evaluated for inhibition against Beta-lactamase TEM derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50114508(CHEMBL46958 | Disodium; (R)-3-carboxy-5,5,8-trioxo...)
Affinity DataIC50:  32nMAssay Description:Inhibitory activity against Class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50114506(CHEMBL44278 | Sodium; (R)-3-[(E)-2-(4-hydroxy-phen...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity against Class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50114525(CHEMBL296738 | Sodium; (R)-5,5,8-trioxo-3-phenyl-7...)
Affinity DataIC50:  38nMAssay Description:Inhibitory activity against Class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50088813(CHEMBL166730 | Sodium; (R)-3-methyl-4-methylene-5,...)
Affinity DataIC50:  39nMAssay Description:Inhibition of Class C beta-lactamase from E. cloacae strain P99More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50114523(CHEMBL45273 | Sodium; (R)-5,5,8-trioxo-7-[1-pyridi...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against Class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50079694(CHEMBL294608 | Sodium; (2S,3R)-3-methyl-4,4,7-trio...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against serine Beta-lactamase derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Covx Research

Curated by ChEMBL
LigandPNGBDBM50197005(CHEMBL436821 | N-[4-{2-[2-(2-{2-[4-(3,5-dioxo-hexy...)
Affinity DataIC50:  44.9nMAssay Description:Displacement of [125I]ET1 from human ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50114515(CHEMBL416447 | Sodium; (R)-3-[(E)-3-(4-methyl-pipe...)
Affinity DataIC50:  53nMAssay Description:Inhibitory activity against class A TEM-1 beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlacenta growth factor(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50339197(CHEMBL1689466)
Affinity DataIC50:  54nMAssay Description:Inhibition of mouse PlGF-VEGFR-1 interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50114522(CHEMBL297671 | Sodium; (R)-3-methylsulfanyl-5,5,8-...)
Affinity DataIC50:  59nMAssay Description:Inhibitory activity against Class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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