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Found 273 with Last Name = 'dunkern' and Initial = 't'
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Nycomed

LigandPNGBDBM248094(VX-497 (2))
Affinity DataIC50:  3.5nMpH: 8.0 T: 2°CAssay Description:The assay was performed in a 100 μL final volume in 96-well UV plates (Costar, 3635) with a reaction buffer composed of 50 mM Tris-HCl (pH 8.0), 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515168(CHEMBL4469291)
Affinity DataIC50:  30nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515126(CHEMBL4451547)
Affinity DataIC50:  40nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515137(CHEMBL4476837)
Affinity DataIC50:  57nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515142(CHEMBL4460134)
Affinity DataIC50:  83nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515156(CHEMBL4542798)
Affinity DataIC50:  120nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Nycomed

LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  130nMpH: 8.0 T: 2°CAssay Description:The assay was performed in a 100 μL final volume in 96-well UV plates (Costar, 3635) with a reaction buffer composed of 50 mM Tris-HCl (pH 8.0), 1...More data for this Ligand-Target Pair
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515170(CHEMBL4483803)
Affinity DataIC50:  210nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Nycomed

LigandPNGBDBM248096(IMPDH II inhibitor, 13)
Affinity DataIC50:  230nMpH: 8.0 T: 2°CAssay Description:The assay was performed in a 100 μL final volume in 96-well UV plates (Costar, 3635) with a reaction buffer composed of 50 mM Tris-HCl (pH 8.0), 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515183(CHEMBL4566276)
Affinity DataIC50:  240nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515153(CHEMBL4444034)
Affinity DataIC50:  280nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515125(CHEMBL4562659)
Affinity DataIC50:  290nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515154(CHEMBL4448675)
Affinity DataIC50:  310nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515161(CHEMBL4467218)
Affinity DataIC50:  310nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM187258(US9169234, 23)
Affinity DataIC50:  310nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515123(CHEMBL4448911)
Affinity DataIC50:  310nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515176(CHEMBL4567010)
Affinity DataIC50:  350nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515150(CHEMBL4437646)
Affinity DataIC50:  370nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Nycomed

LigandPNGBDBM248095(VX-148 (3))
Affinity DataIC50:  380nMpH: 8.0 T: 2°CAssay Description:The assay was performed in a 100 μL final volume in 96-well UV plates (Costar, 3635) with a reaction buffer composed of 50 mM Tris-HCl (pH 8.0), 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515182(CHEMBL4456501)
Affinity DataIC50:  380nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515178(CHEMBL4449470)
Affinity DataIC50:  460nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515169(CHEMBL4521562)
Affinity DataIC50:  520nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515122(CHEMBL4586653)
Affinity DataIC50:  550nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515159(CHEMBL4442449)
Affinity DataIC50:  580nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515181(CHEMBL4566899)
Affinity DataIC50:  600nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515158(CHEMBL4472433)
Affinity DataIC50:  600nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515171(CHEMBL4453841)
Affinity DataIC50:  610nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515165(CHEMBL4585262)
Affinity DataIC50:  610nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515151(CHEMBL4464504)
Affinity DataIC50:  620nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515128(CHEMBL4519901)
Affinity DataIC50:  670nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515157(CHEMBL4460459)
Affinity DataIC50:  680nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515152(CHEMBL4513537)
Affinity DataIC50:  740nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515180(CHEMBL4470398)
Affinity DataIC50:  790nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515145(CHEMBL4556522)
Affinity DataIC50:  980nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515164(CHEMBL4579131)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515172(CHEMBL4546968)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515141(CHEMBL4518154)
Affinity DataIC50:  1.55E+3nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515175(CHEMBL4464213)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515179(CHEMBL4564252)
Affinity DataIC50:  1.68E+3nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515149(CHEMBL4590824)
Affinity DataIC50:  1.99E+3nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515166(CHEMBL4557426)
Affinity DataIC50:  2.32E+3nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515163(CHEMBL4546898)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515184(CHEMBL4446993)
Affinity DataIC50:  2.44E+3nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515155(CHEMBL4469734)
Affinity DataIC50:  2.56E+3nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Nycomed

LigandPNGBDBM248113(IMPDH II inhibitor, 32)
Affinity DataIC50:  3.00E+3nMpH: 8.0 T: 2°CAssay Description:The assay was performed in a 100 μL final volume in 96-well UV plates (Costar, 3635) with a reaction buffer composed of 50 mM Tris-HCl (pH 8.0), 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Nycomed

LigandPNGBDBM248099(IMPDH II inhibitor, 16)
Affinity DataIC50:  3.50E+3nMpH: 8.0 T: 2°CAssay Description:The assay was performed in a 100 μL final volume in 96-well UV plates (Costar, 3635) with a reaction buffer composed of 50 mM Tris-HCl (pH 8.0), 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515133(CHEMBL4438507)
Affinity DataIC50:  4.04E+3nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515144(CHEMBL4445774)
Affinity DataIC50:  4.78E+3nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM29612(CHEMBL33103 | CVD-0001578 | JOH-MSK-a63bdd1d-4 | N...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human sepiapterin reductase using L-sepiapterin as substrate preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSepiapterin reductase(Homo sapiens (Human))
Gr�Nenthal

Curated by ChEMBL
LigandPNGBDBM50515121(CHEMBL4580809)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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